20 Questions
Which of the following is the only depolarizing agent used in anesthesia?
Succinylcholine
What enzyme is NOT responsible for the metabolism of succinylcholine?
Acetylcholinesterase
What is the main consequence of pseudocholinesterase deficiency?
Prolonged paralysis and apnea
What is the dibucaine number?
The percentage of inhibition of plasma cholinesterase by dibucaine
Which of the following can cause permanent pseudocholinesterase deficiency?
Malnutrition, acute infection
Which genetic component is associated with malignant hyperthermia susceptibility?
RYR1 gene
What is the gold standard test for diagnosing malignant hyperthermia susceptibility?
Caffeine-halothane contracture test
Which surgery type is NOT listed as increasing the risk of postoperative nausea and vomiting (PONV)?
Orthopedic surgery
What is the leading cause of delayed post-anesthesia care unit (PACU) discharge?
Postoperative nausea and vomiting (PONV)
What physiological abnormality is characteristic of malignant hyperthermia?
Hypercarbia
Malignant hyperthermia has a greater incidence in adults compared to kids.
False
Succinylcholine and volatile agents trigger malignant hyperthermia in susceptible individuals.
True
Genetic testing for malignant hyperthermia susceptibility is done through the Neostigmine test.
False
Postoperative nausea and vomiting (PONV) is more common in smokers than non-smokers.
False
Myelomeningocele is an associated condition with malignant hyperthermia.
True
Malignant hyperthermia is an anesthesia-specific issue that is not seen unless exposed.
True
Succinylcholine is metabolized by acetylcholinesterase in the liver.
False
Pseudocholinesterase deficiency can lead to prolonged paralysis and apnea.
True
Neostigmine is a drug therapy used in the management of pseudocholinesterase deficiency.
False
What is the gold standard for testing for MH?
caffeine-halothane contracture test
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