Anesthesia-Specific Issues
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Questions and Answers

Which of the following is the only depolarizing agent used in anesthesia?

  • Neostigmine
  • Acetylcholinesterase
  • Succinylcholine (correct)
  • Dibucaine

    • What enzyme is NOT responsible for the metabolism of succinylcholine?

  • Acetylcholinesterase (correct)
  • Butyrylcholinesterase
  • Pseudocholinesterase
  • Plasma cholinesterase

    • What is the main consequence of pseudocholinesterase deficiency?

  • Difficult airway
  • Prolonged paralysis and apnea (correct)
  • Malignant hyperthermia
  • Post-operative nausea and vomiting

    • What is the dibucaine number?

    <p>The percentage of inhibition of plasma cholinesterase by dibucaine</p> Signup and view all the answers

    Which of the following can cause permanent pseudocholinesterase deficiency?

    <p>Malnutrition, acute infection</p> Signup and view all the answers

    Which genetic component is associated with malignant hyperthermia susceptibility?

    <p>RYR1 gene</p> Signup and view all the answers

    What is the gold standard test for diagnosing malignant hyperthermia susceptibility?

    <p>Caffeine-halothane contracture test</p> Signup and view all the answers

    Which surgery type is NOT listed as increasing the risk of postoperative nausea and vomiting (PONV)?

    <p>Orthopedic surgery</p> Signup and view all the answers

    What is the leading cause of delayed post-anesthesia care unit (PACU) discharge?

    <p>Postoperative nausea and vomiting (PONV)</p> Signup and view all the answers

    What physiological abnormality is characteristic of malignant hyperthermia?

    <p>Hypercarbia</p> Signup and view all the answers

    Malignant hyperthermia has a greater incidence in adults compared to kids.

    <p>False</p> Signup and view all the answers

    Succinylcholine and volatile agents trigger malignant hyperthermia in susceptible individuals.

    <p>True</p> Signup and view all the answers

    Genetic testing for malignant hyperthermia susceptibility is done through the Neostigmine test.

    <p>False</p> Signup and view all the answers

    Postoperative nausea and vomiting (PONV) is more common in smokers than non-smokers.

    <p>False</p> Signup and view all the answers

    Myelomeningocele is an associated condition with malignant hyperthermia.

    <p>True</p> Signup and view all the answers

    Malignant hyperthermia is an anesthesia-specific issue that is not seen unless exposed.

    <p>True</p> Signup and view all the answers

    Succinylcholine is metabolized by acetylcholinesterase in the liver.

    <p>False</p> Signup and view all the answers

    Pseudocholinesterase deficiency can lead to prolonged paralysis and apnea.

    <p>True</p> Signup and view all the answers

    Neostigmine is a drug therapy used in the management of pseudocholinesterase deficiency.

    <p>False</p> Signup and view all the answers

    What is the gold standard for testing for MH?

    <p>caffeine-halothane contracture test</p> Signup and view all the answers

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