Anesthesia-Specific Issues

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Questions and Answers

Which of the following is the only depolarizing agent used in anesthesia?

  • Neostigmine
  • Acetylcholinesterase
  • Succinylcholine (correct)
  • Dibucaine

What enzyme is NOT responsible for the metabolism of succinylcholine?

  • Acetylcholinesterase (correct)
  • Butyrylcholinesterase
  • Pseudocholinesterase
  • Plasma cholinesterase

What is the main consequence of pseudocholinesterase deficiency?

  • Difficult airway
  • Prolonged paralysis and apnea (correct)
  • Malignant hyperthermia
  • Post-operative nausea and vomiting

What is the dibucaine number?

<p>The percentage of inhibition of plasma cholinesterase by dibucaine (C)</p> Signup and view all the answers

Which of the following can cause permanent pseudocholinesterase deficiency?

<p>Malnutrition, acute infection (A)</p> Signup and view all the answers

Which genetic component is associated with malignant hyperthermia susceptibility?

<p>RYR1 gene (C)</p> Signup and view all the answers

What is the gold standard test for diagnosing malignant hyperthermia susceptibility?

<p>Caffeine-halothane contracture test (C)</p> Signup and view all the answers

Which surgery type is NOT listed as increasing the risk of postoperative nausea and vomiting (PONV)?

<p>Orthopedic surgery (C)</p> Signup and view all the answers

What is the leading cause of delayed post-anesthesia care unit (PACU) discharge?

<p>Postoperative nausea and vomiting (PONV) (C)</p> Signup and view all the answers

What physiological abnormality is characteristic of malignant hyperthermia?

<p>Hypercarbia (B)</p> Signup and view all the answers

Malignant hyperthermia has a greater incidence in adults compared to kids.

<p>False (B)</p> Signup and view all the answers

Succinylcholine and volatile agents trigger malignant hyperthermia in susceptible individuals.

<p>True (A)</p> Signup and view all the answers

Genetic testing for malignant hyperthermia susceptibility is done through the Neostigmine test.

<p>False (B)</p> Signup and view all the answers

Postoperative nausea and vomiting (PONV) is more common in smokers than non-smokers.

<p>False (B)</p> Signup and view all the answers

Myelomeningocele is an associated condition with malignant hyperthermia.

<p>True (A)</p> Signup and view all the answers

Malignant hyperthermia is an anesthesia-specific issue that is not seen unless exposed.

<p>True (A)</p> Signup and view all the answers

Succinylcholine is metabolized by acetylcholinesterase in the liver.

<p>False (B)</p> Signup and view all the answers

Pseudocholinesterase deficiency can lead to prolonged paralysis and apnea.

<p>True (A)</p> Signup and view all the answers

Neostigmine is a drug therapy used in the management of pseudocholinesterase deficiency.

<p>False (B)</p> Signup and view all the answers

What is the gold standard for testing for MH?

<p>caffeine-halothane contracture test</p> Signup and view all the answers

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