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Questions and Answers
What is a key difference between Mapleson circuits and manual resuscitators?
What is a key difference between Mapleson circuits and manual resuscitators?
What is the primary function of the intake valve in a manual resuscitator?
What is the primary function of the intake valve in a manual resuscitator?
What is the purpose of the outlet valve in a manual resuscitator?
What is the purpose of the outlet valve in a manual resuscitator?
What is a safety feature required in manual resuscitators designed for infants and children?
What is a safety feature required in manual resuscitators designed for infants and children?
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What is a disadvantage of using manual resuscitators?
What is a disadvantage of using manual resuscitators?
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What is a potential risk of using manual resuscitators?
What is a potential risk of using manual resuscitators?
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What is the main reason why Mapleson circuits are not commonly used in today's anesthesia workstation?
What is the main reason why Mapleson circuits are not commonly used in today's anesthesia workstation?
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What is the key difference between Mapleson circuits and Circle Systems?
What is the key difference between Mapleson circuits and Circle Systems?
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In which type of system is rebreathing completely prevented?
In which type of system is rebreathing completely prevented?
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What is the unique feature of the Mapleson A circuit?
What is the unique feature of the Mapleson A circuit?
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What is the disadvantage of the Mapleson A circuit during manual ventilation?
What is the disadvantage of the Mapleson A circuit during manual ventilation?
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What is the Mapleson A R3mix circuit adapted for?
What is the Mapleson A R3mix circuit adapted for?
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What is the main disadvantage of the Mapleson B and C circuits?
What is the main disadvantage of the Mapleson B and C circuits?
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What is the advantage of the Mapleson D circuit during controlled ventilation?
What is the advantage of the Mapleson D circuit during controlled ventilation?
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What is the primary way the nervous system functions?
What is the primary way the nervous system functions?
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What is the modification of the Mapleson D circuit known as?
What is the modification of the Mapleson D circuit known as?
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What is recommended to be performed prior to using the Bain circuit?
What is recommended to be performed prior to using the Bain circuit?
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What is the main reason for using EEG in monitoring the nervous system?
What is the main reason for using EEG in monitoring the nervous system?
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What is the effect of anesthetics on neurons?
What is the effect of anesthetics on neurons?
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What does a pattern that is unpredictable or unexpected in the EEG suggest?
What does a pattern that is unpredictable or unexpected in the EEG suggest?
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What is the traditional approach to understanding anesthetic effects on neurophysiology?
What is the traditional approach to understanding anesthetic effects on neurophysiology?
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What is a characteristic of regional asymmetry in the EEG?
What is a characteristic of regional asymmetry in the EEG?
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What are the components of consciousness?
What are the components of consciousness?
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What is the purpose of EEG in monitoring the nervous system?
What is the purpose of EEG in monitoring the nervous system?
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What is the classification of EEG waveforms based on?
What is the classification of EEG waveforms based on?
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What is the purpose of Fourier Transformation in processed EEG?
What is the purpose of Fourier Transformation in processed EEG?
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What is the characteristic of Beta waves in EEG?
What is the characteristic of Beta waves in EEG?
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What is the range of the BIS index?
What is the range of the BIS index?
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What is the effect of Ketamine on EEG frequencies?
What is the effect of Ketamine on EEG frequencies?
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What is the characteristic of Delta waves in EEG?
What is the characteristic of Delta waves in EEG?
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What is the effect of Opiates on EEG frequencies?
What is the effect of Opiates on EEG frequencies?
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What is the purpose of EEG in clinical scenarios?
What is the purpose of EEG in clinical scenarios?
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What is the effect of anesthesia on EEG waveforms?
What is the effect of anesthesia on EEG waveforms?
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What is the effect of Neuromuscular blockade on EEG indices?
What is the effect of Neuromuscular blockade on EEG indices?
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What is a characteristic of high-voltage spikes and slow waves in the EEG?
What is a characteristic of high-voltage spikes and slow waves in the EEG?
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What is the purpose of processed EEG?
What is the purpose of processed EEG?
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What should be immediately available for all patients with CIED?
What should be immediately available for all patients with CIED?
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What happens when a magnet is placed on a pacemaker?
What happens when a magnet is placed on a pacemaker?
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Why is it important to avoid activating electrosurgery near a CIED?
Why is it important to avoid activating electrosurgery near a CIED?
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What should be done during cardioversion/defibrillation for a patient with a CIED?
What should be done during cardioversion/defibrillation for a patient with a CIED?
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What is a concern during lithotripsy for a patient with a CIED?
What is a concern during lithotripsy for a patient with a CIED?
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What is a consideration for patients with CIED undergoing MRI?
What is a consideration for patients with CIED undergoing MRI?
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What is a characteristic of some older ICD models?
What is a characteristic of some older ICD models?
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What should be done for a patient with a CIED undergoing ECT?
What should be done for a patient with a CIED undergoing ECT?
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A pacemaker can cause myocardial burns during surgery.
A pacemaker can cause myocardial burns during surgery.
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DDD pacing is a type of atrial pacing.
DDD pacing is a type of atrial pacing.
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Temporary pacing and defibrillation equipment should be available for patients with a pacemaker.
Temporary pacing and defibrillation equipment should be available for patients with a pacemaker.
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Bipolar electrosurgery can cause electromagnetic interference with pacemakers.
Bipolar electrosurgery can cause electromagnetic interference with pacemakers.
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A patient with a pacemaker is considered pacer dependent if they have a normal underlying rhythm.
A patient with a pacemaker is considered pacer dependent if they have a normal underlying rhythm.
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Study Notes
Mapleson Circuits
- Not commonly used in modern anesthesia workstations due to economic reasons for volatile anesthetic use
- Differ from Circle Systems in two ways:
- Bidirectional gas flow
- No CO2 absorber
- Depend on high fresh gas flow rates to eliminate CO2 and prevent rebreathing
- Still used in pediatrics, patient transport, procedural sedation, T-piece systems, and office-based airway management
Semi-Closed Systems
- Classification based on reservoir and rebreathing characteristics:
- Open: No reservoir, no rebreathing
- Semi-Open: Reservoir present, no rebreathing
- Semi-Closed: Reservoir present, partial rebreathing
- Closed: Reservoir present, complete rebreathing
Mapleson A (Magill Circuit)
- Functionally distinct from other circuits
- APL located near the patient
- Fresh gas flow enters from the distal end of the circuit
- Disadvantages:
- Pollution
- Can't be used with a ventilator
- Most efficient circuit for spontaneous ventilation if fresh gas flow equals minute ventilation
- Worse efficiency during manual ventilation due to APL location
Mapleson A (R3mix/Lack's Modification)
- Adaptation of Mapleson A to facilitate scavenging of gases
- Added coaxial expiratory limb and expiratory valve moved near the reservoir bag
- Disadvantages:
- Increased work of breathing
- Less efficient fresh gas flow than Magill
Mapleson B & C
- Rarely used
- Similar in assembly, with C having less dead space
- APL and FGF located proximal to the patient
- Extremely inefficient in scavenging and high gas flows
- High fire risk due to APL location
Mapleson D
- Like Mapleson A, but with APL and FGF flipped
- Most efficient during controlled ventilation since FGF pushes alveolar air toward the APL
- Effective at scavenging waste gases due to APL location away from the patient
Mapleson D (RE-mix/Bain Circuit)
- Modification of Mapleson D
- Coaxially placed FGF warms inspired gases
- Used commonly in pediatrics
- Advantages:
- Exhaled gases scavenged
- Recommend Pethick Test prior to use
Manual Resuscitators
- Nonrebreathing valve
- Components:
- Self-inflating reservoir bag
- Nonrebreathing valve (between vent bag and patient)
- Intake valve (between vent and reservoir bag)
- Reservoir valve (with 2 unidirectional valves)
- Disadvantages:
- Lacks visual monitoring cue to patient respiratory effort
- High PIP may be generated, risking barotrauma or gastric insufflation
- Significant variability of tidal volume, PIP, and PEEP
- Nonrebreathing valves generate resistance, increasing the work of breathing
Electroencephalogram (EEG)
- Direct assessment of nervous system function via extracellular electrical potentials
- Utility determined by:
- Hemodynamic effects on electrophysiology
- Pharmacologic effects on action potentials
- Anesthetics hyperpolarize neurons and affect neurotransmitter release/response at the synapse
- Presynaptic glutamate is inhibited, while postsynaptic GABA is potentiated
Nervous System Monitoring
- Historical practice: Physiologic responses to noxious stimuli are explained by the nociceptive-medullary-autonomic circuit
- Traditional physiologic monitors (HR, BP, SpO2) reflect supportive parameters of tissue maintenance
- Anesthetic state of the patient is inferred in this manner
Updated Theories
- CNS functions to exchange information via coordinated action potentials
- Cortical and subcortical structures are critically interconnected
- Growing evidence for top-down mechanism: Intracortical communication becomes interrupted
- Likely, a combination of top-down and bottom-up mechanisms is responsible for suppression of consciousness under anesthesia
EEG
- Pyramidal cells in the cerebral cortex produce large local field potentials via extracellular potentials
- Geometry of neurons creates a biophysical antenna whose potentials can be measured through the scalp
- Neurons exhibit oscillatory spiking and local field potentials that play a primary role in coordinating and modulating communication
- Typical mapping involves placement of 10-20 electrodes
- EEG activity reflects cerebral metabolism and blood flow
- EEG monitoring is useful when cerebral cortex tissue is vulnerable to ischemia or to guide pharmacologic therapy
EEG Waveforms
- Classified according to consistent patterns of amplitude and frequency:
- Delta (0.5-4 Hz)
- Theta (4-8 Hz)
- Alpha (8-13 Hz)
- Beta (13-30 Hz)
- Gamma (30-80 Hz)
- "Activated" waveforms:
- Beta (13-30 Hz)
- Alpha (8-12 Hz)
- "Depressed" waveforms:
- Theta (4-8 Hz)
- Delta (1-4 Hz)
EEG-Based Indices
- Display a dimensionless variable to indicate the level of "wakefulness" created via proprietary algorithms
- GETA induces a change from high values to lower values that indicate states of sedation and unconsciousness
- BIS index: Range 0-100, with values of 60 suggesting reduced probability of consciousness
- GETA is commonly maintained between 45-60
EEG Index Disparities
- Uncertainties exist when using EEG-based indices to define brain states under general anesthesia
- Different anesthetics act at different molecular targets and neural circuits
- The different states of altered consciousness demonstrate different EEG signatures
- These various signatures created by different drugs are readily observed by EEG, but processed EEG indices can confuse or miss certain signals
Pharmacology
- Intravenous hypnotics and volatile anesthetics produce progressive slowing of EEG until burst suppression
- Activation of GABA receptors within the cortical and subcortical structures results in inhibition and disorganized communication
- Characterized by Alpha and Delta oscillations
- Volatiles: at higher doses, Theta bands are present
- N2O (NMDA and K+ sites of action) demonstrate Beta and Gamma oscillations, with synergism existing when combined with other inhalation agents
Miscellaneous
- Neuromuscular blockade: Overlapping frequencies between EEG and Electromyography (EMG) cause interference in values
- Vasoactive agents can affect EEG values
- Standard of care for patients with cardiac implantable electronic devices (CIEDs) undergoing magnet placement:
- Have rescue equipment immediately available
- Avoid activating electrosurgery in the area of the generator
- Magnet placement: Position matters, with varying effects on pacemakers and ICDs
Anesthesia Circuits
- Occlude PT end: useful in MRI suites, allows for ease of connecting to ventilator, and O2 flush to fill circuit
- Disadvantages: disconnection and kinks often go unrecognized
Mapelson Circuits
- Mapelson E: modification of Ayre's T-piece, FGF proximal to patient, no reservoir bag, high fresh gas flows required
- Mapelson F/Jackson-Rees Circuit: modification of Mapelson E, added reservoir bag, commonly used for patient transport
Disadvantages of Mapelson Systems
- High fresh gas flows = high cost
- High pollution
- High FGF = less heat/humidification
- FGF rate difficult to ascertain in correlation to patient minute ventilation
- Inaccessible components depending on setup
- Not suitable for patients at risk of MH
Exceptions
- Mapelson A: only circuit with FGF near the reservoir bag
- Mapelson C: only circuit not corrugated
- Mapelson E: only circuit without a reservoir bag
- Bain & Lack: coaxial tubing
Manual Resuscitators
- Nonrebreathing valve: used consistently during patient transport, emergency resuscitation, or as a back-up supply
EEG
- Anteriorization: EEG pattern in deep anesthetic state, characterized by alpha and delta activity greater in anterior leads
- Burst Suppression: EEG pattern in deep anesthesia, characterized by high-frequency "burst" activity interspersed with flat "suppression" tracings
- Isoelectric: EEG pattern with zero amplitude, seen in deep states of GETA, coma, brain death, and cardiac arrest
- EEG-Based Indices: display a dimensionless variable to indicate level of "wakefulness", commonly used in BIS index
EEG Interpretation
- Accurately identifies consciousness/unconsciousness, stages of sleep, and coma
- Intraop, suggests anatomic or metabolic alterations of the brain
- Regional asymmetry seen with tumors, epilepsy, and cerebral ischemia
Awareness
- GETA requires: Unconsciousness, Amnesia, Analgesia, Immobility, Attenuation of autonomic response
- Awareness: ability to process, integrate, and store information in interaction with the environment
- Lack of awareness is inferred through EEG analysis
Processed EEG
- Manufactures devices that process reduced channel EEG signals
- Examines 4 components within the EEG associated with the anesthetic state
- Various devices: BIS sensor, PSArray, Narcotrend, Entropy Module, Cerebral State Monitor
Pharmacology
- Intravenous hypnotics & Volatile anesthetics produce progressive slowing of EEG until burst suppression
- Ketamine: creates false excitatory values, increases Theta and Beta/Gamma frequencies
- Dexmedetomidine: initially increases Alpha waves, at high doses, primarily Delta waves
- Opiates: decrease Beta, slow Alpha, and increase Delta, reduce wave variability
EMG
- Active or Evoked EMG: helps identify intact nerves, used to identify a nerve or anatomic variances in order to avoid cutting it
- Passive or Spontaneous EMG: commonly used in spine surgery to identify nerve irritation before injury
Cardiac Implantable Electronic Devices (CIEDs)
- Refers to any permanently implanted pacemaker, cardioverter-defibrillator, or cardiac resynchronization therapy devices
- Utilization is increasing due to growing geriatric populations and prevalence of cardiovascular disease
Pacemakers
- Pacemaker placement is indicated for symptomatic bradyarrhythmia and atrioventricular conduction defects likely to progress to complete heart block
- Have 1-2 leads placed atrial +/- ventricular and a pulse generator
- Generator transmits electrical pulse through the lead/s to depolarize local myocardium
Indications
- Expanded indications for pacemaker implantation include:
- Sinus node dysfunction
- Symptomatic bradycardia
- AV block
- Cardiomyopathy
- Heart failure
- Neurocardiogenic syncope
- Post heart transplant
- Terminating tachycardia
- Congenital heart disease
Intraop Considerations
- Intraoperative complications related to CIEDs:
- Inhibition of pacing
- Inappropriate antitachycardia therapy
- "Runaway" pacemaker
- Reprogramming
- Rate adaptive pacing interference
- Myocardial burns
- Complete device failure
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