Questions and Answers
What is the commonest form of crescentic or rapidly progressive glomerulonephritis?
What is the main characteristic of the renal lesion in ANCA-associated glomerulonephritis?
Which specific antibody reactivity pattern is associated with a serine proteinase called proteinase 3 (PR3)?
In which condition are raised ANCA titres generally detectable during active disease, and rising titres may herald a relapse?
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What is the debated role of ANCAs in vasculitis?
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Which pattern of ANCA reactivity is associated with a perinuclear pattern (pANCA)?
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What is the most common form of vasculitic process seen in ANCA-associated glomerulonephritis?
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What is the main characteristic of the renal lesion in ANCA-associated glomerulonephritis?
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Which condition is associated with some cANCA/pANCA positive sera reacting with neutrophil antigens other than PR3/MPO?
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What do rising ANCA titres generally indicate in granulomatosis with polyangiitis?
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