Anatomy Unit 201: Cell Cycle and Gametogenesis
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Anatomy Unit 201: Cell Cycle and Gametogenesis

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Questions and Answers

When do the oogonia enter meiosis I and undergo DNA replication to form primary oocytes?

  • During fetal life (correct)
  • With each ovarian cycle
  • At birth
  • At puberty
  • Following fertilization
  • What is the main difference between mitosis and meiosis?

    Mitosis is somatic cell division for growth and repair, while meiosis is a reduction division that produces gametes.

    What are the two main processes in spermatogenesis?

    Spermatocytogenesis and spermiogenesis.

    Where does oogenesis occur?

    <p>In the outer cortex of the ovary.</p> Signup and view all the answers

    What is the function of seminal fluid?

    <p>All of the above</p> Signup and view all the answers

    What is azospermia?

    <p>The absence of sperm in semen.</p> Signup and view all the answers

    Meiosis involves DNA replication before the second meiotic division.

    <p>False</p> Signup and view all the answers

    How many primary oocytes are present in the ovaries of newborn females?

    <p>2 million.</p> Signup and view all the answers

    The secondary oocyte is expelled at ovulation.

    <p>True</p> Signup and view all the answers

    Study Notes

    Cell Cycle and Gametogenesis

    • The cell cycle consists of interphase (growth and DNA replication) and the mitotic phase (cell division).
    • Mitosis is somatic cell division, occurring in somatic tissues for growth and repair.
    • Meiosis is gametic cell division, taking place in gonads (testes and ovaries) to produce gametes.

    Mitosis vs. Meiosis

    • Mitosis results in two identical daughter cells, maintaining the diploid chromosome number.
    • Meiosis consists of two divisions: meiosis I (reduction division) and meiosis II, resulting in four haploid gametes.
    • Meiosis I includes DNA replication and crossing over; no DNA replication occurs in meiosis II.

    Importance of Meiosis

    • Reduces diploid chromosome number (2n) to haploid (n) for reproductive purposes.
    • Facilitates genetic diversity through shuffling of chromosomes and crossing over.

    Spermatogenesis

    • Transformation of spermatogonia into spermatozoa, occurring in seminiferous tubules of the testes.
    • Duration of spermatogenesis is approximately 64 days, starting at puberty and continuing throughout life.
    • Comprises spermatocytogenesis (division of spermatogonia into spermatids) and spermiogenesis (maturation of spermatids).

    Seminal Fluid Characteristics

    • Volume: 3-5 cc; has a characteristic odor and alkaline reaction.
    • Contains about 200-600 million sperm per ejaculation; motility exceeding 80%.
    • Provides nutrients (fructose) for sperm, prostaglandins for motility, and balances vaginal acidity.

    Abnormalities in Seminal Fluid

    • Azospermia: absence of sperm in semen.
    • Oligospermia: low sperm count.
    • Necrospermia: presence of dead sperm.
    • Morphological abnormalities: giant or dwarf sperm, abnormal head/tail counts; should not exceed 20%, normally under 10%.

    Oogenesis

    • Oogenesis is the process of forming mature ova from oogonia in the ovarian cortex.
    • Primary oocytes begin meiosis I during fetal life but remain dormant until puberty.
    • Monthly during the menstrual cycle, 5-12 primary oocytes complete meiosis I, forming a secondary oocyte and a polar body.
    • Secondary oocyte completes meiosis II only upon fertilization, arrested in metaphase prior to this.

    Oocyte Statistics

    • Total primary oocytes in newborn females: approximately 2 million, decreasing to about 40,000 during adolescence.
    • Only around 480 primary oocytes are ovulated throughout a woman’s reproductive life.

    Comparison of Gametogenesis

    • Male gametogenesis (spermatogenesis) produces multiple sperm continuously, while female gametogenesis (oogenesis) produces limited ova with cyclic release.
    • Male gametes are smaller and more numerous; female gametes are larger and fewer.

    Case Scenario

    • Questions regarding the timing of oocyte maturation emphasize that oogonia enter meiosis I and replicate DNA during fetal life.

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    Description

    This quiz covers the essential concepts of the cell cycle, focusing on mitosis and meiosis. It includes a comparison between spermatogenesis and oogenesis, highlighting their differences and end results. Test your understanding of the maturation of female gametes and the stages involved.

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