Anatomy of Antibodies

Antibody Definition

• An antibody, also known as immunoglobulin (Ig), is a glycoprotein produced by plasma cells that identifies and neutralizes pathogens like bacteria and viruses.

Function of BCR Antibodies

• B cell receptors (BCR) are specific antibodies on the surface of B cells that recognize antigens, initiating the immune response.
• BCRs play a crucial role in the activation and differentiation of B cells, leading to the production of more antibodies.

Location of Antibodies in the Body

• Antibodies are primarily found in blood plasma but are also present in other bodily fluids such as lymph and saliva, as well as in mucosal secretions.

Origin of the Name 'Antibody' or 'Immunoglobulin'

• The term 'antibody' originates from their function in binding to antigens, with 'immunoglobulin' reflecting their role in the immune system as globular proteins that mediate immune responses.

Percentage of Total Protein Represented by Antibodies

• Antibodies account for approximately 20% of total protein in serum, indicating their significant presence and function in the immune system.

Test your knowledge of antibody structure and production with this quiz. Learn about the definition of antibodies, their antigen recognition abilities, and the origin of their name. Explore the role of immunoglobulins and their different regions.