Anatomy and Physiology Quiz

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Questions and Answers

What type of tissue primarily composes the epidermis?

  • Nervous tissue
  • Connective tissue
  • Epithelial tissue (correct)
  • Muscle tissue

Which layer of skin is responsible for producing melanin?

  • Stratum granulosum
  • Stratum lucidum
  • Stratum corneum
  • Stratum basale (correct)

Which type of gland is primarily responsible for sweating and responding to temperature?

  • Eccrine gland (correct)
  • Ceruminous gland
  • Mammillary gland
  • Sebaceous gland

Which statement accurately describes the function of the ribosomes?

<p>Ribosomes can exist freely in the cytoplasm or attached to the rough ER. (A)</p> Signup and view all the answers

What is the main function of keratinocytes in the epidermis?

<p>To produce keratin (C)</p> Signup and view all the answers

What role do lysosomes play in a cell?

<p>They contain enzymes that break down cellular waste and debris. (D)</p> Signup and view all the answers

Which structure is responsible for anchoring the hair follicle to the skin?

<p>Bulb (C)</p> Signup and view all the answers

What is the primary function of the Golgi apparatus?

<p>To modify, package, and store proteins for export. (B)</p> Signup and view all the answers

What type of connective tissue makes up the reticular layer of the dermis?

<p>Dense irregular connective tissue (A)</p> Signup and view all the answers

Which of the following correctly explains the structure of the cell membrane?

<p>It is composed of a phospholipid bilayer with embedded molecules for stability and function. (D)</p> Signup and view all the answers

Which of the following correctly describes the hypodermis?

<p>Connects the skin to underlying structures (A)</p> Signup and view all the answers

Which type of receptor in the dermis specifically detects pain?

<p>Nociceptor (B)</p> Signup and view all the answers

What distinguishes prokaryotes from eukaryotes?

<p>Eukaryotes contain a nucleus and membrane-bound organelles, while prokaryotes do not. (C)</p> Signup and view all the answers

Which molecule is NOT embedded in the phospholipid bilayer of the cell membrane?

<p>RNA (D)</p> Signup and view all the answers

What is the primary role of adipose tissue in the hypodermis?

<p>Stores fat and provides insulation (C)</p> Signup and view all the answers

What layer of skin is typically burned in a second-degree burn?

<p>Epidermis and dermis (C)</p> Signup and view all the answers

What is the function of the cytoskeleton?

<p>It helps maintain cell shape and facilitates cell movement. (C)</p> Signup and view all the answers

What is the role of the nucleolus within the nucleus?

<p>To produce ribosomes that are essential for protein synthesis. (D)</p> Signup and view all the answers

In which structure does cellular respiration primarily take place?

<p>Mitochondria (B)</p> Signup and view all the answers

Which of these functions is NOT associated with the function of smooth endoplasmic reticulum (ER)?

<p>Protein synthesis (C)</p> Signup and view all the answers

What is the primary function of epithelial tissue?

<p>Covers surfaces, lines cavities, and forms glands (A)</p> Signup and view all the answers

Which cell type is primarily responsible for producing collagen fibers in dense connective tissue?

<p>Fibroblasts (D)</p> Signup and view all the answers

What characterizes cardiac muscle tissue?

<p>It is striated and can have one or two nuclei (B)</p> Signup and view all the answers

What distinguishes a hypertonic solution from a hypotonic solution?

<p>Hypertonic solutions have more solute concentration than the cell (D)</p> Signup and view all the answers

In which phase of the cell cycle does DNA replication occur?

<p>S phase (D)</p> Signup and view all the answers

Which type of connective tissue serves as a protective cushion around organs and stores energy?

<p>Loose connective tissue (C)</p> Signup and view all the answers

What role do microvilli play in epithelial tissue?

<p>To increase surface area for absorption (D)</p> Signup and view all the answers

Which type of muscular tissue is both striated and involuntary?

<p>Cardiac muscle (A)</p> Signup and view all the answers

What is the primary job of neutrophils, a type of leukocyte?

<p>Attack and destroy pathogens (C)</p> Signup and view all the answers

Which type of tissue primarily assists in conducting electrical impulses?

<p>Nervous tissue (B)</p> Signup and view all the answers

During which phase of mitosis do chromosomes align at the cell's equatorial plane?

<p>Metaphase (C)</p> Signup and view all the answers

Which characteristic is true regarding smooth muscle?

<p>It is non-striated and involuntary (C)</p> Signup and view all the answers

What type of epithelial tissue can change shape between squamous and cuboidal?

<p>Transitional (A)</p> Signup and view all the answers

What distinguishes true ribs from false ribs?

<p>True ribs attach to the sternum by costal cartilage. (C)</p> Signup and view all the answers

Which of the following describes the axis vertebra?

<p>It allows for head rotation. (C)</p> Signup and view all the answers

Which vertebrae are referred to as lumbar vertebrae?

<p>L1 to L5 (A)</p> Signup and view all the answers

What is the primary function of the hyoid bone?

<p>To protect the air way. (C)</p> Signup and view all the answers

What is unique about the clavicle compared to other bones in the pectoral girdle?

<p>It is longer than it is wide. (C)</p> Signup and view all the answers

Which part of the appendicular skeleton provides attachment for the legs?

<p>Pelvic girdle (A)</p> Signup and view all the answers

In which order are the components of the upper extremity named?

<p>Proximal to distal (C)</p> Signup and view all the answers

What is the function of the tibia in the lower leg?

<p>To bear weight. (B)</p> Signup and view all the answers

What characterizes the shape of the female pelvis compared to the male pelvis?

<p>It has a larger pubic arch. (D)</p> Signup and view all the answers

What is the largest bone in the human skeleton?

<p>Femur (A)</p> Signup and view all the answers

What type of skin cancer is known for its fast spread and difficulty in treatment?

<p>Melanoma (B)</p> Signup and view all the answers

Which cells are responsible for breaking down bone tissue?

<p>Osteoclasts (D)</p> Signup and view all the answers

What is the primary function of osteocytes in bone tissue?

<p>Maintain bone tissue (D)</p> Signup and view all the answers

Which type of bone is primarily responsible for hemopoiesis?

<p>Spongy bone (B)</p> Signup and view all the answers

What is the primary role of collagen in bone tissue?

<p>Provide structural integrity (B)</p> Signup and view all the answers

What distinguishes the periosteum from the endosteum?

<p>Periosteum covers the outside of the bone, while endosteum lines internal cavities. (C)</p> Signup and view all the answers

Which structure is primarily found in the central canal of osteons?

<p>Blood vessels and nerves (D)</p> Signup and view all the answers

How do chondrocytes contribute to the process of bone growth?

<p>They undergo mitosis and hypertrophy to increase bone length. (A)</p> Signup and view all the answers

Which of these bones is classified as irregular?

<p>Vertebra (A)</p> Signup and view all the answers

What is the role of osteogenic cells in bone tissue?

<p>They generate new bone cells. (D)</p> Signup and view all the answers

What process primarily leads to the formation of long bones during fetal development?

<p>Endochondral ossification (A)</p> Signup and view all the answers

Which of the following bones is part of the axial skeleton?

<p>Mandible (B)</p> Signup and view all the answers

What effect does hypercalcemia have on bone health?

<p>It leads to increased osteoblast activity, making bones harder. (B)</p> Signup and view all the answers

Which term refers to the bone's ability to resist bending and twisting?

<p>Compressive strength (B)</p> Signup and view all the answers

What type of joint is characterized as immovable?

<p>Synarthrosis (C)</p> Signup and view all the answers

Which joint is an example of a hinge joint?

<p>Knee joint (A)</p> Signup and view all the answers

What is the primary function of ligaments?

<p>Holding bones together at a joint (D)</p> Signup and view all the answers

Which type of muscle tissue is classified as involuntary?

<p>Cardiac muscle (C)</p> Signup and view all the answers

What does the term 'external' refer to in the structure of skeletal muscle cells?

<p>Sarcolemma (B)</p> Signup and view all the answers

Which joint movement involves moving a limb away from the midline of the body?

<p>Abduction (D)</p> Signup and view all the answers

Which of the following statements is true regarding synovial joints?

<p>They contain a joint cavity lined with synovial membrane (B)</p> Signup and view all the answers

What change occurs to intervertebral discs throughout the day?

<p>They become thicker during weight-bearing activity (A)</p> Signup and view all the answers

What is the role of myoglobin in skeletal muscle cells?

<p>Stores oxygen (A)</p> Signup and view all the answers

Which classification of joint allows for a significant range of motion?

<p>Synovial (A)</p> Signup and view all the answers

Which joint allows for opposition movement?

<p>Wrist joint (D)</p> Signup and view all the answers

What occurs as we age that affects synovial joints?

<p>Production of synovial fluid decreases (D)</p> Signup and view all the answers

What defines a 'saddle' joint?

<p>One end is shaped like a saddle (A)</p> Signup and view all the answers

What characterizes cardiac muscle cells?

<p>Branching structure with one or two nuclei (B)</p> Signup and view all the answers

What is the primary function of acetylcholine in muscle physiology?

<p>It transmits the signal from neuron to muscle cell (B)</p> Signup and view all the answers

Which component of the muscle cell structure allows for the rapid spread of action potential?

<p>T-tubules (A)</p> Signup and view all the answers

What is the effect of lactic acid on muscle physiology during intense exercise?

<p>It causes muscle fatigue (C)</p> Signup and view all the answers

Which type of muscle fiber is associated with endurance and prolonged activities?

<p>Slow twitch fibers (D)</p> Signup and view all the answers

During muscle contraction, which process occurs first?

<p>Action potential occurs in the muscle cell (B)</p> Signup and view all the answers

What type of muscle contraction occurs when the muscle length changes?

<p>Both B and C (C)</p> Signup and view all the answers

Which of the following best describes the role of the sarcoplasmic reticulum in muscle cells?

<p>It stores and releases calcium (A)</p> Signup and view all the answers

What is the primary energy source for muscle contraction during high-intensity activities?

<p>Creatine phosphate (D)</p> Signup and view all the answers

Which structure is responsible for connecting muscle to bone?

<p>Tendon (C)</p> Signup and view all the answers

What occurs during the relaxation phase of muscle contraction?

<p>Acetylcholine is broken down (B)</p> Signup and view all the answers

What happens to calcium ions after a muscle has contracted?

<p>They are pumped back into the sarcoplasmic reticulum (B)</p> Signup and view all the answers

Which feature distinguishes cardiac muscle from skeletal muscle?

<p>Presence of intercalated disks (D)</p> Signup and view all the answers

What characterizes smooth muscle tissue?

<p>Self-stimulating activity (D)</p> Signup and view all the answers

What type of pain is characterized by being sudden and short-term, allowing the person to identify exactly where it hurts?

<p>Acute pain (C)</p> Signup and view all the answers

Which type of receptors are responsible for detecting temperature?

<p>Thermoreceptors (B)</p> Signup and view all the answers

Where are the mechanoreceptors responsible for proprioception primarily located?

<p>In the muscles (A)</p> Signup and view all the answers

What is the primary role of dendrites in a neuron?

<p>Collect data from the environment (D)</p> Signup and view all the answers

Which cranial nerve is involved in the sense of smell?

<p>CN I (B)</p> Signup and view all the answers

Which cell type is responsible for supporting neurons?

<p>Neuroglia (D)</p> Signup and view all the answers

What classification do the senses of taste and smell fall under?

<p>Visceral senses (B)</p> Signup and view all the answers

What structure connects the middle ear to the throat and helps equalize pressure?

<p>Eustachian tube (A)</p> Signup and view all the answers

What type of neuron is primarily responsible for transmitting information from the brain to a body part?

<p>Motor neuron (C)</p> Signup and view all the answers

Which fluid is found in the cochlea's scala media?

<p>Endolymph (D)</p> Signup and view all the answers

What initiates the creation of an action potential in a neuron?

<p>Signals reaching the axon hillock (C)</p> Signup and view all the answers

Where do the sensory messages from balance receptors in the inner ear eventually get sent?

<p>Cerebellum and brainstem (B)</p> Signup and view all the answers

What is the function of the sodium-potassium pump in a neuron?

<p>To establish resting membrane potential (A)</p> Signup and view all the answers

Which part of the eye is responsible for focusing light onto the retina?

<p>Lens (D)</p> Signup and view all the answers

Which neurotransmitter is primarily involved in muscle contraction?

<p>Acetylcholine (D)</p> Signup and view all the answers

Which area of the brain is primarily responsible for producing speech?

<p>Broca area (D)</p> Signup and view all the answers

What type of memory is primarily involved in skills like riding a bike?

<p>Procedural memory (A)</p> Signup and view all the answers

What is the primary function of the rods in the retina?

<p>Night vision (B)</p> Signup and view all the answers

Which type of reflex involves a quick, involuntary reaction and is processed through the spinal cord?

<p>Spinal reflex (D)</p> Signup and view all the answers

The pathway for general senses involves which of the following sequences?

<p>Receptor → 1st sensory neuron → Thalamus (C)</p> Signup and view all the answers

What nerve transmits sound signals from the cochlea to the brain?

<p>CN VIII (B)</p> Signup and view all the answers

What part of the brain is primarily responsible for coordination of movement?

<p>Cerebellum (D)</p> Signup and view all the answers

Which cranial nerve is solely responsible for hearing?

<p>Vestibulocochlear nerve (B)</p> Signup and view all the answers

Which stimulus is NOT detected by free nerve endings?

<p>Light (C)</p> Signup and view all the answers

Which neurotransmitter is associated with excitatory cholinergic receptors in muscle contraction?

<p>Acetylcholine (C)</p> Signup and view all the answers

Which of the following structures plays a role in detecting changes in homeostasis?

<p>Chemoreceptors (C)</p> Signup and view all the answers

What is the primary purpose of the sympathetic nervous system?

<p>Preparation for fight or flight (A)</p> Signup and view all the answers

Which layer of the meninges is the outermost and toughest?

<p>Dura mater (C)</p> Signup and view all the answers

What is the function of hair cells in the cochlea?

<p>Transduce sound vibrations into neural signals (B)</p> Signup and view all the answers

Which part of the autonomic nervous system is primarily involved in maintaining homeostasis?

<p>Parasympathetic division (D)</p> Signup and view all the answers

What is the primary function of the thalamus in the brain?

<p>Process sensory information (A)</p> Signup and view all the answers

Which neurotransmitter is primarily associated with pleasure and motivation?

<p>Dopamine (B)</p> Signup and view all the answers

Where are long-term memories primarily consolidated?

<p>Hippocampus (B)</p> Signup and view all the answers

Which type of sensory receptor detects changes in chemical concentrations?

<p>Chemoreceptor (D)</p> Signup and view all the answers

What structure in the spinal cord is responsible for carrying motor messages away from the CNS?

<p>Anterior horns (B)</p> Signup and view all the answers

Which neurons are involved in the autonomic nervous system response?

<p>Upper and lower motor neurons plus post-ganglionic LMNs (A)</p> Signup and view all the answers

What effect does hyperpolarization have on a neuron?

<p>Decreases the likelihood of action potential (D)</p> Signup and view all the answers

Which part of the neuron is specialized for the transmission of action potentials?

<p>Axon (B)</p> Signup and view all the answers

What role does glutamate play in short-term memory?

<p>It enhances excitatory signaling for memory retention. (C)</p> Signup and view all the answers

Which area of the brain connects the Wernicke and Broca areas?

<p>Arcuate fasciculus (D)</p> Signup and view all the answers

What defines sensory adaptation?

<p>Decreased sensitivity after constant stimulation (D)</p> Signup and view all the answers

What type of neural pathway does the 1st sensory neuron follow in the general senses pathway?

<p>Receptor to Spinal nerve (B)</p> Signup and view all the answers

Which type of memory retains information for a lifespan?

<p>Long-term memory (A)</p> Signup and view all the answers

Flashcards

Cell Theory

The fundamental theory stating that all living organisms are composed of cells and that all cells arise from pre-existing cells.

Cellular Differentiation

The process by which cells specialize in structure and function due to the activation of specific genes within their DNA.

Prokaryotic Cells

Simple, small cells lacking a nucleus and other membrane-bound organelles, found in bacteria.

Eukaryotic Cells

Complex, larger cells with a nucleus and membrane-bound organelles, found in humans and other multicellular organisms.

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Plasma Membrane

The outer boundary of a cell, a phospholipid bilayer that regulates the passage of molecules in and out.

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Cytoplasm

The gel-like substance within the cell membrane, containing the cytosol and organelles.

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Organelles

Specialized structures within a cell, like mini organs, performing specific functions.

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Nucleus

The control center of the cell, containing DNA, a blueprint for all cellular activities.

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Ribosomes

Small, granular structures that manufacture proteins, essential for all cellular functions.

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Mitochondria

Powerhouses of the cell, responsible for cellular respiration, converting nutrients into energy (ATP).

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Osmosis

Movement of water across a semi-permeable membrane from a region of high water concentration to a region of low water concentration.

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Hypertonic Solution

A solution with a higher concentration of solutes than the cell. Water moves out of the cell, causing it to shrink.

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Hypotonic Solution

A solution with a lower concentration of solutes than the cell. Water moves into the cell, causing it to swell.

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Isotonic Solution

A solution with the same concentration of solutes as the cell. Water moves equally in and out of the cell, maintaining a stable size.

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Facilitated Diffusion

Movement of molecules across a membrane with the help of a carrier protein, going down the concentration gradient.

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Active Transport

Movement of molecules across a membrane against their concentration gradient, requiring energy.

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Exocytosis

Process by which cells release substances outside the cell using vesicles that fuse with the cell membrane.

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Endocytosis

Process by which cells take in substances from outside the cell, forming vesicles that pinch off from the cell membrane.

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Phagocytosis

A type of endocytosis where cells engulf large particles, like bacteria.

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Pinocytosis

A type of endocytosis where cells take in small particles and fluids.

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Receptor-mediated Endocytosis

A type of endocytosis where cells take in specific substances by binding to receptors on the cell surface.

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Ion Pumps

Proteins that use energy to move ions across a membrane against their concentration gradient.

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Interphase

The stage of the cell cycle where the cell grows and replicates its DNA.

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Mitosis

The process of cell division that produces two identical daughter cells from one parent cell.

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Meiosis

The process of cell division that produces four non-identical daughter cells from one parent cell, used for sexual reproduction.

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What are the four signs of inflammation?

Redness, swelling, warmth, and pain are the classic signs of inflammation, indicating the body's response to injury or infection.

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What is the difference between regeneration and replacement in tissue repair?

Regeneration completely restores damaged tissue to its original state, while replacement involves scar tissue formation, typically after severe injury.

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What is the function of the integumentary system?

The integumentary system, comprised of skin and its appendages, acts as a protective barrier against environmental factors, regulates temperature, and plays a role in sensory perception.

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What are the layers of the epidermis?

The epidermis, the outermost layer of skin, is composed of five layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum (thick skin only), and stratum corneum.

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What is keratin, and where is it produced?

Keratin is a tough, water-resistant protein produced by keratinocytes, the primary cells of the epidermis. It forms the protective outer layer of the skin and structures like nails and hair.

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What are the two main layers of the dermis?

The dermis, the layer beneath the epidermis, is comprised of the papillary layer, a superficial layer containing areolar connective tissue, and the reticular layer, a deeper layer composed of dense irregular connective tissue.

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What is the difference between apocrine and eccrine sweat glands?

Apocrine sweat glands are active after puberty and release pheromones, while eccrine sweat glands regulate body temperature and are present from birth.

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What is the function of the arrector pili muscle?

The arrector pili muscle, located near hair follicles, contracts in response to cold or emotional stimuli, causing hair to stand up and creating goosebumps.

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Describe the role of sensory receptors in the dermis.

Sensory receptors in the dermis detect various external stimuli, including temperature changes (thermoreceptors), pressure (mechanoreceptors), and tissue damage (nociceptors), sending signals to the brain for processing.

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Explain the difference between 1st, 2nd, and 3rd degree burns.

1st degree burns affect the epidermis, causing redness. 2nd degree burns damage the dermis, leading to blisters. 3rd degree burns destroy all skin layers, potentially reaching the hypodermis.

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True Ribs

The upper ribs that directly attach to the sternum by costal cartilage.

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False Ribs

The lower ribs that do not directly attach to the sternum.

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Floating Ribs

The last two pairs of ribs (R11, L11 and R12, L12) that are not attached to the sternum.

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Vertebral Column

The backbone, made up of 24 individual bones called vertebrae, all with a central hole for the spinal cord.

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Cervical Vertebrae

The first seven bones of the spine, located in the neck.

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Thoracic Vertebrae

The 12 vertebrae located in the chest region, starting after the cervical vertebrae.

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Lumbar Vertebrae

The five vertebrae in the lower back, starting after the thoracic vertebrae.

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Sacrum

A bone formed by the fusion of five vertebrae at the base of the vertebral column.

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Coccyx

The tailbone, formed by the fusion of a few vertebrae.

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Hyoid Bone

The only bone in the skeleton that does not articulate with another bone. Located in the upper front of the neck, it protects the airway and provides attachment for tongue and swallowing muscles.

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What are joints?

Joints, or articulations, are where two or more bones meet. They allow for movement and growth.

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What are Ligaments?

Ligaments are strong, dense connective tissues that connect bones to each other. They provide stability and restrict excessive movement.

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What is a Synarthrosis joint?

A Synarthrosis joint is an immovable joint. It provides stability but no movement.

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What is an Amphiarthrosis joint?

An Amphiarthrosis joint is a slightly movable joint. It allows for limited movement.

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What is a Diarthrosis joint?

A Diarthrosis joint is a freely movable joint. It enables a wide range of motions.

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What are Fibrous Joints?

In Fibrous joints, bones are connected by strong collagen fibers. These joints are often immobile.

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What are Cartilaginous Joints?

Cartilaginous joints have a layer of cartilage between the bones. They allow for a limited degree of movement.

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What are Synovial Joints?

Synovial joints have a joint cavity filled with synovial fluid. They are highly mobile and have a wide range of movement.

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What is a Ball and Socket Joint?

A ball and socket joint allows for movement in all directions. One bone end is a ball and the other is a socket.

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What is a Condyloid Joint?

A Condyloid joint allows for movement in two planes, like the movement of your knuckles.

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What is a Gliding Joint?

A Gliding joint allows for minor sliding and gliding movements.

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What is a Pivot Joint?

A Pivot joint allows for rotation around a central axis, like turning your head.

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What is a Hinge Joint?

A Hinge joint allows for movement in one plane, like bending your arm.

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What is a Saddle Joint?

A Saddle joint allows for movement in two planes, like the movement of your thumb.

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What is Opposition?

Opposition is a unique movement that allows the thumb to touch other fingers, enabling grasping.

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What is melanoma?

A type of skin cancer that originates from melanocytes (cells that produce melanin) and spreads rapidly, making it difficult to treat. It starts in the epidermis and spreads to the dermis.

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What is basal cell carcinoma (BCC)?

A type of skin cancer that originates from cells in the stratum basale (bottommost layer of the epidermis). It spreads slowly from the epidermis to the dermis, making it easier to treat.

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What is squamous cell carcinoma (SCC)?

A type of skin cancer that originates from any cell in the epidermis except melanocytes and basal cells. It spreads very slowly, making it very easy to treat.

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Osteogenic cells

Stem cells found in bone tissue that continuously produce osteoblasts, the baby cells that will develop into mature bone cells.

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Osteoblasts

Baby cells produced by osteogenic cells that secrete the bone matrix. They eventually mature into osteocytes.

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Osteocytes

Mature bone cells responsible for maintaining the health of bone tissue. They reside in lacunae (small cavities) within the bone matrix.

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Osteoclasts

Cells formed by the fusion of white blood cells. Their job is to break down bone matrix.

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What is the function of compact bone tissue?

Compact bone is the solid part of a bone and is located on the outside layer. It's designed to handle weight and stress. The tightly packed structure allows for the flow of blood through tiny canals called osteons.

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What are osteons (Haversian systems)?

Microscopic structures within compact bone that allow for blood flow and nutrient delivery to bone cells. Each osteon is a circular unit with a central canal running through it.

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What is spongy bone tissue?

Spongy bone tissue is a lighter, porous type of bone that is found inside bones. It is designed for flexibility and to allow for the production of blood cells.

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What is red marrow?

Red bone marrow is found within the spaces of spongy bone tissue. It's responsible for producing blood cells.

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What is the function of the periosteum?

The periosteum is a membrane that covers the outside of a bone. It contains cells that can form new bone and aids in bone repair.

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What is the function of the endosteum?

The endosteum is a membrane that lines the cavities inside bones. It contains cells that can help with bone remodeling and repair.

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What are the two main types of bone formation?

There are two main types of bone formation:

  1. Endochondral ossification: This process involves cartilage being replaced by bone and is how most bones in our bodies form.
  2. Intramembranous ossification: This process involves bone forming directly from a fibrous membrane and mainly creates flat bones.
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What is a fracture repair?

A fracture repair is the process of healing a bone break. It starts with a blood clot forming at the fracture site (hematoma). The blood clot brings nutrients and white blood cells to the area, which then leads to the formation of new bone by osteoblasts. Osteoclasts then reshape the bone, bringing it back to its normal shape.

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Sensory Neurons

Nerve cells that transmit signals from the body's sensory receptors to the central nervous system (CNS).

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Motor Neurons

Nerve cells that carry signals from the CNS to muscles and glands, causing them to contract or secrete.

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Interneurons

Nerve cells that connect other neurons within the CNS, acting as intermediaries in neural pathways.

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Dendrites

Branching extensions of a neuron that receive signals from other neurons or sensory receptors.

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Axon

A long, slender extension of a neuron that transmits signals from the cell body to other neurons or effector cells.

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Synapse

The junction between a neuron and another cell, where a signal is transmitted from one cell to the next.

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Neurotransmitters

Chemical messengers released by neurons at synapses, carrying signals across the synaptic cleft.

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Action Potential

A brief electrical impulse that travels down the axon, transmitting a signal from one end of the neuron to the other.

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Resting Membrane Potential

The electrical difference across the membrane of a neuron when it is not actively sending a signal.

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Depolarization

A change in membrane potential that makes the inside of the cell more positive, bringing it closer to the threshold for generating an action potential.

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Repolarization

The process of restoring the membrane potential of a neuron to its resting state after an action potential.

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Myelin

A fatty substance that insulates axons, allowing for faster and more efficient transmission of action potentials.

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Spinal Cord

A long, cylindrical structure that transmits signals between the brain and the rest of the body.

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Reflex Arc

A neural pathway that produces a rapid, involuntary response to a stimulus.

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Cerebrum

The largest part of the brain, responsible for higher-level functions like thinking, planning, and decision-making.

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What does a motor neuron do?

Motor neurons transmit signals from the brain and spinal cord to muscle cells, causing them to contract.

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What is a motor unit?

A motor unit consists of a single motor neuron and all the muscle fibers it innervates. These muscle fibers will either all contract or all relax together.

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What's the main role of dendrites?

Dendrites are extensions of a neuron that receive signals from other neurons.

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What does the axon do?

The axon is a long, slender extension of a neuron that transmits signals away from the cell body.

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What is the neuromuscular junction?

The neuromuscular junction is the specialized synapse where a motor neuron communicates with a muscle fiber.

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What is acetylcholine (Ach)?

Acetylcholine (Ach) is a neurotransmitter that plays a key role in muscle contraction. It is released from the motor neuron at the neuromuscular junction.

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Explain depolarization in muscle contraction.

Depolarization is the change in electrical charge across the muscle cell membrane where the inside becomes more positive and the outside becomes more negative. This triggers muscle contraction.

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What are T-tubules?

T-tubules are extensions of the muscle cell membrane that carry the action potential (electrical signal) deep into the muscle fiber.

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How does calcium (Ca+) play a role in muscle contraction?

Calcium ions (Ca+) are released from the sarcoplasmic reticulum (SR) and bind to troponin, causing a shift that exposes the binding sites on actin for myosin to attach.

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Describe the sliding filament theory.

The sliding filament theory explains muscle contraction as the sliding of the thin filaments (actin) over the thick filaments (myosin) within the sarcomere.

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How is ATP involved in muscle contraction?

ATP provides the energy needed for myosin to detach from actin, allowing the cycle of muscle contraction to continue.

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What is creatine phosphate?

Creatine phosphate is a high-energy molecule stored in muscle cells. It can quickly donate a phosphate group to ADP to regenerate ATP for short bursts of energy.

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What is glycolysis?

Glycolysis is a metabolic pathway that breaks down glucose into pyruvate, producing a small amount of ATP (2) without oxygen.

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What is aerobic respiration?

Aerobic respiration is a metabolic process that occurs in the mitochondria and uses oxygen to break down pyruvate, producing a large amount of ATP (30+).

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What is anaerobic respiration?

Anaerobic respiration occurs when oxygen is limited. Pyruvate is converted into lactic acid, producing no ATP but regenerating materials for glycolysis.

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Upper Motor Neuron (UMN)

A neuron that originates in the brain and travels through the medulla oblongata to the spinal cord, controlling voluntary movement.

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Lower Motor Neuron (LMN)

A neuron that originates in the spinal cord and directly innervates skeletal muscle fibers, transmitting signals for muscle contraction.

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Acetylcholine (Ach)

A neurotransmitter that acts on excitatory cholinergic receptors in skeletal muscle to initiate muscle contraction.

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Lateralization of Brain Function

The specialization of each hemisphere of the brain for certain functions, with the left side typically responsible for language and the right side for spatial processing.

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Wernicke Area

A sensory area in the parietal lobe responsible for processing incoming language information, enabling speech comprehension.

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Broca Area

A motor area in the frontal lobe responsible for planning and coordinating muscle movements involved in speech production.

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Arcuate Fasciculus

A bundle of nerve fibers that connects the Wernicke and Broca areas, facilitating communication between language processing and speech production.

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Working Memory

A temporary storage system for information actively being used during a task, typically lasting only a few seconds to minutes.

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Short-Term Memory

The ability to retain information for a short period, typically minutes to days, enabling retention of recent events.

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Long-Term Memory

The ability to store information for extended periods, often years to a lifetime, allowing recall of past experiences.

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What are thermoreceptors?

Specialized nerve endings that detect temperature changes, found in the skin and internal organs.

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What are nociceptors?

Free nerve endings in the skin and internal organs that detect tissue damage, causing the sensation of pain.

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What is the difference between acute and chronic pain?

Acute pain is sudden, sharp, and localized, often lasting a short time. Chronic pain persists for a longer period, often with a dull, aching quality.

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What is referred pain?

Pain that is felt in a location different from the source of the pain, often due to shared nerve pathways in the body.

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What is proprioception?

The sense of body position and movement, detected by mechanoreceptors in muscles and tendons.

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What are the muscle spindle and Golgi tendon organ?

Specialized mechanoreceptors in muscles and tendons, respectively, that help sense muscle stretch and tension.

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What are the three types of visceral senses?

Visceral senses detect internal organ activity, including conscious pain and pressure (free nerve endings, mechanoreceptors), and unconscious changes in homeostasis (mechanoreceptors, chemoreceptors).

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What is olfaction?

The sense of smell, detected by chemoreceptors in the olfactory organs of the nasal cavity.

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What are the five primary taste sensations?

The five primary taste sensations are salty, sweet, umami (savory), sour, and bitter.

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Describe the path of sound waves through the ear.

Sound waves enter the outer ear, travel through the external auditory canal, vibrate the tympanic membrane, and then pass through the middle ear via the auditory ossicles (malleus, incus, stapes) to the oval window, which transmits vibrations to the inner ear's cochlea.

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What is the cochlea?

A spiral-shaped structure in the inner ear filled with fluid that converts sound vibrations into electrical signals that are sent to the brain.

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What is the function of the vestibular apparatus?

The vestibular apparatus in the inner ear is responsible for detecting balance and equilibrium, using mechanoreceptors sensitive to head movement.

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What are photoreceptors, and where are they found?

Photoreceptors, specifically rods and cones, are specialized cells in the retina of the eye that detect light and convert it into electrical signals.

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Describe the flow of light through the eye.

Light enters the eye through the cornea, passes through the pupil (controlled by the iris), and is focused by the lens onto the retina, where photoreceptors convert light into electrical signals.

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What are the two types of motor neurons involved in sending messages to muscles?

The two types are upper motor neurons (UMN) and lower motor neurons (LMN). UMNs originate in the brain and descend to the medulla oblongata, where they synapse with LMNs. LMNs then carry the signal from the medulla oblongata to the spinal cord and finally to the muscle fiber.

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What is the role of acetylcholine (Ach) in muscle contraction?

Acetylcholine (Ach) is a neurotransmitter released by the lower motor neuron at the neuromuscular junction. It binds to receptors on the muscle fiber, triggering depolarization and initiating muscle contraction.

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What is the contralateral control of movement?

Contralateral control means that the left side of the brain controls the right side of the body, and vice versa.

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What is the Wernicke area and its function?

The Wernicke area is located in the parietal lobe and is responsible for processing incoming language information. It allows us to comprehend speech.

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What is the Broca area and its function?

The Broca area is located in the frontal lobe and is responsible for controlling the muscles involved in speech production.

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What is the arcuate fasciculus and what does it do?

The arcuate fasciculus is a bundle of nerve fibers that connects the Wernicke and Broca areas. It allows for the smooth flow of information between the two areas, enabling us to understand and produce speech.

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What are the differences between working, short-term, and long-term memory?

Working memory is temporary and task-oriented, used for immediate tasks like following directions. Short-term memory lasts minutes to days, storing information like where you parked your car. Long-term memory persists for years or a lifetime, holding memories like your first day of high school.

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How does the brain use glutamate to form short-term memories?

Glutamate, an excitatory neurotransmitter, plays a role in strengthening synaptic connections during short-term memory formation. This increased activity helps maintain the memory trace.

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What is the process of memory consolidation?

Memory consolidation is the process of converting fragile short-term memories into more stable long-term memories. It involves strengthening synaptic connections and reorganizing neural networks.

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What are the two types of explicit memory?

Declarative/explicit memory includes two subtypes: semantic memory (facts and general knowledge) and episodic memory (personal experiences).

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What are the roles of the hippocampus and amygdala in memory?

The hippocampus is crucial for the formation and retrieval of new memories, especially facts. The amygdala processes emotions and helps link those emotions to memories, making emotionally charged events more memorable.

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What is procedural/implicit memory?

Procedural memory stores skills and habits you've learned, like riding a bike. These memories are often unconscious and automatic.

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What brain areas are involved in procedural memory?

The cerebellum, responsible for coordination, and the premotor cortex, involved in planning movements, both contribute to the formation and execution of learned motor skills stored as procedural memory.

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What is the autonomic nervous system (ANS) and its purpose?

The autonomic nervous system controls involuntary bodily functions like heart rate, digestion, and breathing. It works automatically to maintain homeostasis.

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What are the three main neurons involved in the ANS pathway?

The ANS pathway involves a chain of three neurons: the upper motor neuron (starts in the hypothalamus or medulla), the pre-ganglionic neuron (connects to a ganglion), and the post-ganglionic neuron (extends to the target organ).

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Study Notes

Cell Theory and Structure

  • Basic unit of life: Cells are the fundamental building blocks of all living organisms.
  • Cells originate from pre-existing cells: All cells arise from the division of other cells.
  • Cellular differentiation: Cells specialize to perform specific functions through selective gene activation.
    • Prokaryotes: Simple, small cells found in bacteria.
    • Eukaryotes: Complex, larger cells found in organisms like humans.

Eukaryotic Cell Structure

  • Plasma membrane: Encloses the cell, regulates passage of substances.
  • Cytoplasm: The entire region inside the cell membrane, including cytosol and organelles.
  • Cytosol/Intracellular fluid: Primarily water, responsible for internal transport within the cell.
  • Organelles: Specialized structures within the cytoplasm performing specific functions.

Animal Cell Organelles

  • Nucleus: The largest organelle; contains DNA, site of ribosome production.
    • Nuclear envelope: The "skin" of the nucleus, containing pores for selective transport.
    • Nucleolus: Structure within the nucleus that produces ribosomes.
    • Chromatin: Loose DNA strands, present during interphase (when cell is not dividing).
    • Chromosomes: Condensed DNA strands visible during cell division.
  • Ribosomes: Involved in protein synthesis, found free in the cytoplasm or attached to the endoplasmic reticulum.
    • Free ribosomes synthesize proteins for use within the cell.
    • Ribosomes attached to rough ER synthesize proteins for export.
  • Endoplasmic Reticulum (ER): Network of flattened tubes.
    • Smooth ER: No ribosomes; involved in detoxification, lipid metabolism, and storage.
    • Rough ER: Ribosomes attached; involved in protein synthesis for export.
  • Golgi complex/apparatus: Stack of flattened tubes.
    • Cis face: Receives proteins from the rough ER.
    • Modifies proteins and packages them into vesicles.
    • Trans face: Where vesicles leave the Golgi complex to be transported.
  • Lysosomes: Contain hydrolytic enzymes to break down substances.
  • Peroxisomes: Break down hydrogen peroxide (H2O2) using oxidative enzymes.
  • Mitochondria: Bean-shaped organelles, site of cellular respiration (ATP production).
    • Aerobic respiration: Requires oxygen to produce ATP.
  • Cytoskeleton: Framework of proteins providing cell structure, movement, and support.
    • Microtubules: Small tubes that form the cytoskeleton.
      • Centrioles: Pairs of microtubule structures near the nucleus, involved in chromosome movement during cell division.
      • Cilia: Short hair-like projections for movement or sweeping of substances across a cell surface.
      • Flagella: Long tail-like extensions for cell movement (e.g., sperm cells).
    • Intermediate filaments: Medium-sized fibers providing structural support.
    • Microfilaments: Small, solid fibers involved in cell contraction and movement.
      • Microvilli: Small bumps on a cell surface that increase surface area for absorption (e.g., intestines).
  • Cell membrane:
    • Phospholipid bilayer: Two layers of phospholipids forming the membrane's basic structure.
    • Embedded molecules: Cholesterol (stability) and proteins (chemical reactions) and glycoproteins (cell recognition).
    • Selectively permeable: Controls what enters and exits the cell.

Cell Transport

  • Passive transport: Movement of substances across the membrane without energy.
    • Filtration: Movement driven by hydrostatic pressure.
    • Simple diffusion: Movement down a concentration gradient.
    • Osmosis: Movement of water across a selectively permeable membrane.
      • Tonicity: Relation of solute concentrations across a membrane (hypertonic, hypotonic, isotonic).
    • Facilitated diffusion: Movement down a concentration gradient using a carrier protein.
  • Active transport: Movement of substances against a concentration gradient using energy.
    • Exocytosis: Vesicles fuse with the membrane to release substances outside the cell.
    • Endocytosis: The cell absorbs substances by engulfing them into vesicles.
      • Phagocytosis ("cell eating").
      • Pinocytosis ("cell drinking").
      • Receptor-mediated endocytosis.

Cell Cycle

  • Interphase: Period of cell growth and DNA replication.
    • G0: Non-dividing state.
    • G1: Growth and protein synthesis.
    • S: DNA synthesis.
    • G2: Preparation for cell division.
  • Cell division: Mitosis (somatic cells) and meiosis (sex cells).

Tissue Level (Histology)

  • Animal tissues (epithelial, connective, muscle, nervous).

Epithelial Tissue

  • Locations: Covers surfaces, lines cavities, forms glands.
  • Characteristics: Avascular, apical surface, basement membrane.
  • Cell shape: Squamous, cuboidal, columnar.
  • Cell layers: Simple or stratified (single or multiple layers).

Connective Tissue

  • Extracellular matrix: Supports cells, composed of protein fibers and ground substance.
  • Types:
    • Loose connective tissue: Fibers and cells are spread apart.
      • Areolar: Under skin.
      • Adipose: Stores fat.
      • Reticular: Traps foreign bodies/ germs.
    • Dense connective tissue: Fibers and cells are closely packed.
      • Regular: Parallel fibers in ligaments and tendons.
      • Irregular: Random fibers in organ capsules.
      • Elastic: Elastic fibers in lungs.
    • Specialized connective tissue.
      • Bone tissue: Osteocytes (bone cells), minerals and collagen.
      • Cartilage: Chondrocytes, hyaline, elastic, fibrocartilage.
      • Blood: Erythrocytes (red blood cells), leukocytes (white blood cells), platelets.
      • Lymph: Fluid in the immune system containing leukocytes.

Muscle Tissue

  • Types:
    • Skeletal: Attached to bones, striated, voluntary.
    • Cardiac: Found in heart, striated, involuntary.
    • Smooth: Found in viscera, non-striated, involuntary.

Nervous Tissue

  • Neurons: Specialized cells transmitting information.
  • Neuroglia/Glial cells: Support neurons (many types).

Tissue Membranes

  • Layers of tissues forming protective barriers.
    • Mucous: Lines cavities to the outside.
    • Serous: Lines cavities not to the outside.
    • Synovial: Lines joint cavities.
    • Cutaneous: Covers external surface of body (skin).

Tissue Growth and Repair

  • Stem cells: Undifferentiated cells able to divide.
  • Specialization: Stem cells dividing, one cell remaining a stem cell the other differentiates.
  • Repair: Healing of damaged tissue through inflammation, regeneration, or replacement.

Integumentary System (Skin)

  • Epidermis: Outer layer (epithelial tissue).
  • Dermis: Inner layer (connective, muscle, and nervous tissues).
  • Hypodermis/Subcutaneous: Connects skin to body (CT).

Epidermis

  • Stratified squamous epithelium.
  • Keratinocytes: Produce keratin.
  • Melanocytes: Produce melanin.
  • Nails: Made of keratin.
  • Chemical Reactions: Vitamin D synthesis from UV light.

Dermis

  • Papillary and reticular layers: Contain blood vessels, glands, sensory receptors.
    • Hair follicle, hair shaft, arrector pili muscle, sebaceous gland, sudoriferous gland, ceruminous gland, mammary gland, blood vessels, and nervous tissue.

Hypodermis

  • Adipose tissue: Stores fat, insulates, and cushions.

Disorders

  • Burns: Classified by degree (1st, 2nd, 3rd, 4th).
  • Lesions: Abnormal skin areas (blisters, pustules, etc.).
  • Skin cancer: Various types, melanoma (fastest spreading).

Skeletal System

  • Bone tissue:
    • Cells: Osteogenic cells, osteoblasts, osteocytes, osteoclasts.
    • Matrix: Minerals (calcium), collagen.
    • Compact bone: Dense, outer layer, Haversian systems.
    • Spongy bone: Inner layer, trabeculae, red marrow.
    • Bone markings: Openings, depressions, projections.
  • Bone shape: Flat, long, short, round/sesamoid, irregular.
  • Long bone anatomy: Epiphysis, diaphysis, medullary cavity, periosteum, endosteum, articular cartilage, nutrient foramen.

Osteogenesis

  • Endochondral ossification: Cartilage replaced by bone.
    • Primary ossification center: Bone formation begins in the diaphysis.
    • Secondary ossification centers: Bone formation at the epiphyses.
    • Growth plates: Cartilage separating epiphysis and diaphysis.
  • Intramembranous ossification: Bone formation directly from fibrous membrane.
  • Fracture repair: Hematoma formation, callus formation, bone remodeling.

Calcium Homeostasis

  • Hypercalcemia: Calcitonin stimulates bone formation, excretes calcium.
  • Hypocalcemia: Parathyroid hormone stimulates bone resorption, increases calcium absorption.

Skeletal System Functions

  • Support, shape, storage of minerals/lipids, hematopoiesis, protection, movement, growth.

Skeleton

  • Axial skeleton: Skull, thoracic cage, vertebral column.
    • Skull bones: Cranial and facial (various bones and structures, including sinuses).
    • Thoracic cage: Sternum, ribs.
    • Vertebral column: Vertebrae (cervical, thoracic, lumbar, sacrum, coccyx).
  • Appendicular skeleton: Pectoral girdle, upper extremity, pelvic girdle, lower extremity.
    • Pectoral girdle: Clavicles, scapulae.
    • Upper extremity: Humerus, ulna, radius, carpals, metacarpals, phalanges.
    • Pelvic girdle: Os coxae.
    • Lower extremity: Femur, patella, tibia, fibula, tarsals, metatarsals, phalanges.

Joints

  • Articulations: Where bones meet.
  • Classification by movement: Synarthrosis (immovable), amphiarthrosis (slightly movable), diarthrosis (freely movable).
  • Classification by tissues: Fibrous, cartilaginous, synovial.
    • Synovial joints: Structure, types (ball and socket, condyloid, gliding, pivot, hinge, saddle), movements (flexion, extension, abduction, adduction, rotation, circumduction, elevation, depression, protraction, retraction, supination, pronation, inversion, eversion, dorsiflexion, plantar flexion).
  • Joint changes: Sutures, epiphyseal plates, intervertebral discs.

Muscular System

  • Skeletal muscle: Types of muscle fibers (slow twitch, fast twitch, intermediate).
  • Skeletal muscle functions: Produce movement, maintain posture, control openings, produce heat.
  • Skeletal muscle anatomy: Attachments (origin, insertion), action, functional groups (agonists, antagonists, synergists), innervation.
  • Muscle names (location, direction, size, attachments, action, and shape).

Nervous System

  • CNS: Brain and spinal cord.
  • PNS: Nerves.

Nervous Tissue

  • Neurons: Cells transmitting information.
  • Neuroglia: Supporting cells (many types).
  • Neuron structure: Dendrites, soma, axon, axon terminals.
  • Nerve classification: By function (sensory, motor, interneuron) and structure (unipolar, bipolar, multipolar).

Synapses

  • Synaptic cleft: Space between presynaptic and postsynaptic cells.
  • Neurotransmitters: Chemical messengers.

Action Potential

  • Resting membrane potential: -70 mV.
  • Depolarization: Inside of cell becomes more positive.
  • Action potential: Electrical signal propagated down the axon.
  • Repolarization: Inside of cell returns to negative.
  • Synaptic transmission: Release of neurotransmitters at synapse.

Neurotransmitters

  • Acetylcholine (ACh): Common excitatory neurotransmitter.
  • Monoamines (e.g., norepinephrine, dopamine, serotonin): Various functions.
  • Amino acids (e.g., glutamate, GABA): Excitatory or inhibitory.

Spinal Cord and Spinal Nerves

  • Spinal cord: Gray and white matter, meninges, nerve roots, spinal nerves, rami, plexuses, dermatomes.
  • Spinal reflexes: Involuntary reactions (e.g., knee-jerk reflex).

Brain

  • Brain regions (cerebrum, cerebellum, diencephalon, brain stem).
  • Ventricles: Cavities filled with CSF.
  • Meninges: Membranes covering the brain and spinal cord.
  • Cranial nerves: Names, functions, sensory, motor, or both.

Integration of Nervous System

  • Somatic nervous system: Conscious control of skeletal muscles.
  • Higher brain functions: Speech, memory (working and long-term), declarative memory, procedural memory.

Autonomic Nervous System

  • Divisions (sympathetic, parasympathetic): Effects on viscera.

Senses

  • Sensory receptors: Detect changes, convert stimuli to signals.
  • Classification by stimuli (chemoreceptors, nociceptors, thermoreceptors, mechanoreceptors, photoreceptors).
  • Classification by structure (free nerve endings, corpuscles).
  • Sensory adaptation: Receptors adjust to constant stimulation.
  • General senses; location, pathways.
    • Somatic senses (touch, pressure, temperature, pain, proprioception); visceral senses (internal organs).

Special Senses

  • Smell (olfaction): Chemoreceptors in upper nasal cavity.
  • Taste (gustation): Chemoreceptors in taste buds.
  • Hearing (auditory): Mechanoreceptors in cochlea.
  • Balance (equilibrium): Mechanoreceptors in vestibular apparatus.
  • Sight (vision): Photoreceptors in retina.

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