Anaphylactic Shock: Pathophysiology and Prevention
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Questions and Answers

What is the primary goal of nursing care in anaphylactic reactions?

  • Maintaining an adequate airway (correct)
  • Educating patients on prevention and treatment
  • Monitoring patient response to the antigen
  • Instituting comfort measures related to dermatological manifestations
  • What is the consequence of increased capillary permeability in anaphylactic shock?

  • Decrease in preload
  • Increase in blood pressure
  • Loss of vascular volume (correct)
  • Increase in cardiac output
  • What is the primary mechanism by which platelet activating factor 2 contributes to the development of hypotension and cardiovascular dysfunction?

  • By increasing capillary permeability
  • The mechanism is not yet fully understood (correct)
  • By inducing coronary vasoconstriction
  • By causing systemic vasodilatation
  • What is the estimated percentage of patients with severe sepsis who may never have an identifiable site of infection?

    <p>20-30%</p> Signup and view all the answers

    What is the primary mechanism of neurogenic shock?

    <p>Loss of sympathetic tone</p> Signup and view all the answers

    What is the effect of parasympathetic stimulation on vascular smooth muscle?

    <p>Relaxation or dilation</p> Signup and view all the answers

    Which of the following is NOT a clinical manifestation of anaphylactic shock?

    <p>Fever</p> Signup and view all the answers

    What is the purpose of medical identification for patients with known allergies?

    <p>To alert medical professionals to the patient's allergy</p> Signup and view all the answers

    What is the medical management of anaphylactic shock?

    <p>Intravenous crystalloid and intravenous hydrocortisone</p> Signup and view all the answers

    What is the role of histamine in anaphylactic shock?

    <p>Causing systemic vasodilatation and increased capillary permeability</p> Signup and view all the answers

    What is the purpose of elevating the head of the bed at least 30 degrees in patients receiving spinal or epidural anesthesia?

    <p>To prevent neurogenic shock</p> Signup and view all the answers

    What is the most common causative microorganism of septic shock?

    <p>Gram-negative bacteria</p> Signup and view all the answers

    Study Notes

    Anaphylactic Shock

    • Anaphylactic shock is a life-threatening condition that can occur rapidly, but can often be prevented.
    • Patients with known allergies should understand the consequences of subsequent exposure to the antigen and wear medical identification listing their sensitivities.
    • The antibody-antigen reaction causes the release of substances such as histamines, eosinophil substance, heparin, prostaglandins, leukotrienes, and platelet activating factor 2.
    • These substances cause systemic vasodilatation, increased capillary permeability, broncho-constriction, coronary vasoconstriction, and urticaria.
    • Clinical manifestations of anaphylactic shock include:
      • Generalized erythema
      • Urticaria and pruritus
      • Anxiety
      • Restlessness
      • Dyspnea
      • Wheezing
      • Chest tightness
      • A warm feeling
      • Nausea and vomiting
      • Angioedema (swelling of the lips, face, neck, and throat)
      • Abdominal pain
    • Medical management of anaphylactic shock involves:
      • Intravenous crystalloid
      • Intravenous hydrocortisone
      • Antihistaminic
      • ETT may be needed if laryngeal oedema and steroid are developed
    • Nursing management involves maintaining an adequate airway, monitoring patient response to the antigen, and providing comfort measures related to dermatological manifestations.

    Neurogenic Shock

    • Neurogenic shock occurs as a result of a loss of balance between parasympathetic and sympathetic stimulation.
    • Causes of neurogenic shock include:
      • Spinal cord injury
      • Spinal anesthesia
      • Nervous system damage
      • Depressant action of medications
      • Lack of glucose (e.g. insulin reaction or shock)
    • Clinical manifestations of neurogenic shock include:
      • Hypotension
      • Bradycardia
      • Warm, dry extremities
      • Peripheral vasodilatation and venous pooling
      • Decreased cardiac output (with cervical or high thoracic injury)
    • Medical management of neurogenic shock involves restoring sympathetic tone by positioning the patient properly.
    • Specific treatment depends on the cause of the shock.
    • Nursing management involves elevating the head of the bed at least 30 degrees to prevent neurogenic shock when the patient receives spinal or epidural anesthesia.

    Septic Shock

    • Septic shock is a complex and generalized process that involves all organ systems.
    • Sepsis, severe sepsis, and septic shock represent progressive stages of the same illness.
    • The most common causative microorganisms of septic shock are gram-negative bacteria, followed by gram-positive bacteria.
    • Other infectious agents, such as viruses and fungi, can also cause septic shock.
    • It is estimated that 20-30% of patients with severe sepsis may never have an identifiable site of infection.

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    Description

    Test your knowledge of anaphylactic shock, a life-threatening allergic reaction that can occur rapidly. Learn about the pathophysiology of anaphylaxis and how it can be prevented. Understand the importance of medical identification for patients with known allergies.

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