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What is the main mechanism of action of NSAIDs?
What is the main mechanism of action of NSAIDs?
- Activation of thromboxane synthesis
- Inhibition of cyclooxygenase enzymes 1 and 2 (correct)
- Induction of COX-1 and COX-2
- Stimulation of prostacyclin production
Which enzyme is responsible for the analgesic, antipyretic, and anti-inflammatory activity of salicylates?
Which enzyme is responsible for the analgesic, antipyretic, and anti-inflammatory activity of salicylates?
- Prostaglandins
- COX-2
- Thromboxane
- COX-1 (correct)
Which type of NSAIDs inhibits both COX-1 and COX-2?
Which type of NSAIDs inhibits both COX-1 and COX-2?
- Selective NSAIDs
- Non-selective NSAIDs (correct)
- Prostacyclin inhibitors
- Coxibs
Where is COX-2 widely expressed and highly inducible?
Where is COX-2 widely expressed and highly inducible?
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What is the main function of thromboxane?
What is the main function of thromboxane?
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Which enzyme is responsible for regulating normal cellular processes?
Which enzyme is responsible for regulating normal cellular processes?
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In states of inflammation, which enzyme is highly inducible and leads to the production of proinflammatory prostaglandins?
In states of inflammation, which enzyme is highly inducible and leads to the production of proinflammatory prostaglandins?
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Which type of NSAID inhibits both COX-1 and COX-2?
Which type of NSAID inhibits both COX-1 and COX-2?
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What is the main mechanism of action of NSAIDs?
What is the main mechanism of action of NSAIDs?
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Which enzyme is responsible for the analgesic, antipyretic, and anti-inflammatory activity of salicylates?
Which enzyme is responsible for the analgesic, antipyretic, and anti-inflammatory activity of salicylates?
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