Ampicillin/Sulbactam (Unasyn) Flashcards

What classification does ampicillin/sulbactam (Unasyn) belong to?

Which of the following are indications for ampicillin/sulbactam? (Select all that apply)

What are the contraindications for ampicillin/sulbactam?

What are some common side effects of ampicillin/sulbactam? (Select all that apply)

What are the adverse reactions associated with ampicillin/sulbactam?

The onset for IM administration of ampicillin/sulbactam is ____ and the duration is 6-8 hours.

What is the adult dosage for ampicillin/sulbactam?

What dosage of ampicillin is recommended for infants greater than 1 month old?

Classification

Ampicillin/sulbactam (Unasyn) belongs to the therapeutic classification of anti-infectives.

Indications

Effective for treating skin and soft tissue infections.
Used for otitis media, intra-abdominal infections, sinusitis, and respiratory infections.
Indicated for genitourinary infections, meningitis, and septicemia.

Contraindications

Not recommended for individuals with hypersensitivity to penicillins or sulbactam.

Side Effects

Common side effects include diarrhea, nausea, vomiting, and rash.
Urticaria, blood dyscrasias, and injection site pain (both IM and IV) may also occur.

Adverse Reactions

Serious adverse reactions can include seizures and pseudomembranous colitis.

Route, Onset, Peak, and Duration

Administered intramuscularly (IM) with a rapid onset, peak effectiveness at 1 hour, and duration of 6-8 hours.
Intravenous (IV) administration leads to immediate onset, peak at the end of infusion, and duration of 6-8 hours.

Dosage

For adults and children over 40 kg: IM & IV dosage ranges from 1-2 g of ampicillin every 6-8 hours, with a maximum of 12 g per day.
Children over 1 year: 100-200 mg ampicillin/kg/day divided every 6 hours; for meningitis, the dosage is increased to 200-400 mg/kg/day divided every 6 hours, max 8 g/day.
Infants over 1 month: 100-150 mg ampicillin/kg/day divided every 6 hours.

Test your knowledge of Ampicillin/Sulbactam, a combination of anti-infectives. This quiz covers therapeutic classifications, indications, and contraindications related to its use. Perfect for medical students and healthcare professionals alike.