Questions and Answers
What classification does ampicillin/sulbactam (Unasyn) belong to?
Which of the following are indications for ampicillin/sulbactam? (Select all that apply)
What are the contraindications for ampicillin/sulbactam?
Hypersensitivity to penicillins or sulbactam
What are some common side effects of ampicillin/sulbactam? (Select all that apply)
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What are the adverse reactions associated with ampicillin/sulbactam?
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The onset for IM administration of ampicillin/sulbactam is ____ and the duration is 6-8 hours.
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What is the adult dosage for ampicillin/sulbactam?
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What dosage of ampicillin is recommended for infants greater than 1 month old?
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Study Notes
Classification
- Ampicillin/sulbactam (Unasyn) belongs to the therapeutic classification of anti-infectives.
Indications
- Effective for treating skin and soft tissue infections.
- Used for otitis media, intra-abdominal infections, sinusitis, and respiratory infections.
- Indicated for genitourinary infections, meningitis, and septicemia.
Contraindications
- Not recommended for individuals with hypersensitivity to penicillins or sulbactam.
Side Effects
- Common side effects include diarrhea, nausea, vomiting, and rash.
- Urticaria, blood dyscrasias, and injection site pain (both IM and IV) may also occur.
Adverse Reactions
- Serious adverse reactions can include seizures and pseudomembranous colitis.
Route, Onset, Peak, and Duration
- Administered intramuscularly (IM) with a rapid onset, peak effectiveness at 1 hour, and duration of 6-8 hours.
- Intravenous (IV) administration leads to immediate onset, peak at the end of infusion, and duration of 6-8 hours.
Dosage
- For adults and children over 40 kg: IM & IV dosage ranges from 1-2 g of ampicillin every 6-8 hours, with a maximum of 12 g per day.
- Children over 1 year: 100-200 mg ampicillin/kg/day divided every 6 hours; for meningitis, the dosage is increased to 200-400 mg/kg/day divided every 6 hours, max 8 g/day.
- Infants over 1 month: 100-150 mg ampicillin/kg/day divided every 6 hours.
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Description
Test your knowledge of Ampicillin/Sulbactam, a combination of anti-infectives. This quiz covers therapeutic classifications, indications, and contraindications related to its use. Perfect for medical students and healthcare professionals alike.
