Amphotericin B Mechanism of Action
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Questions and Answers

What is the mechanism of action of amphotericin B?

Amphotericin B binds to ergosterol in the plasma membranes of sensitive fungal cells, disrupting membrane function and leading to cell death.

Which fungi is amphotericin B effective against?

Amphotericin B is effective against a wide range of fungi, including Candida albicans, Histoplasma capsulatum, Cryptococcus neoformans, Coccidioides immitis, Blastomyces dermatitidis, and many strains of Aspergillus.

How is amphotericin B administered?

Amphotericin B is administered by slow, intravenous (IV) infusion.

Name three adverse effects associated with the use of amphotericin B.

<p>a. Renal impairment b. Hypotension c. Anemia</p> Signup and view all the answers

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