Amphetamine & Dextroamphetamine Flashcards

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Questions and Answers

What is the brand name for Amphetamine/Dextroamphetamine?

  • Adderall XR (correct)
  • Ritalin
  • Vyvanse
  • Concerta

What is the classification of Amphetamine/Dextroamphetamine?

CNS stimulant, anorexiant, sympathomimetic

List two therapeutic uses of Amphetamine/Dextroamphetamine.

ADHD, autism spectrum

What is the mechanism of action (MOA) of Amphetamine/Dextroamphetamine?

<p>Produces sympathomimetic effects and CNS stimulation, using norepinephrine and serotonin.</p> Signup and view all the answers

Name two adverse effects of Amphetamine/Dextroamphetamine.

<p>Irritability, insomnia</p> Signup and view all the answers

What are some contraindications for Amphetamine/Dextroamphetamine?

<p>Caffeine, other CNS stimulants, melatonin, DM, glaucoma, HTN + hyperthyroidism, Tourette syndrome</p> Signup and view all the answers

What are key nursing considerations for Amphetamine/Dextroamphetamine?

<p>Long-term use may stunt growth; psychosis can occur with overdose; it is a Schedule 2 drug.</p> Signup and view all the answers

What is the recommended treatment for an overdose of Amphetamine/Dextroamphetamine?

<p>Gastric lavage + chlorpromazine</p> Signup and view all the answers

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Study Notes

Amphetamine/Dextroamphetamine Overview

  • Amphetamine/Dextroamphetamine is known by the brand name Adderall XR.
  • Classified as a CNS stimulant, anorexiant, and sympathomimetic agent.

Therapeutic Uses

  • Primarily used for treating ADHD (Attention Deficit Hyperactivity Disorder).
  • Also indicated for individuals on the autism spectrum.

Mechanism of Action

  • Produces sympathomimetic and CNS stimulation effects.
  • Acts on the cerebral cortex and reticular activating system, utilizing norepinephrine and serotonin pathways.

Adverse Effects

  • Can cause excessive CNS and peripheral stimulation leading to:
    • Irritability and insomnia
    • Nervousness and palpitations
    • Increased blood pressure and tachycardia
    • Weight loss and anxiety
    • Tremors and psychosis, especially in overdose situations.

Contraindications

  • Should be avoided in conjunction with:
    • Caffeine and other CNS stimulants
    • Melatonin, diabetes mellitus, glaucoma
    • Hypertension, hyperthyroidism, and Tourette syndrome.

Nursing Considerations

  • Long-term use may stunt growth, but growth typically normalizes after discontinuation.
  • Monitor for signs of psychosis due to overdose.
  • Classified as a Schedule II controlled substance.

Overdose Management

  • Treatment includes gastric lavage and administration of chlorpromazine.

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