Amoebicides

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Questions and Answers

Which route of transmission is responsible for the spread of amoebiasis?

  • Waterborne transmission
  • Faeco-oral transmission (correct)
  • Vector-borne transmission
  • Airborne transmission

Which type of amoebicides act on trophozoites in the gut lumen and kill them?

  • Nitroimidazoles
  • Luminal amoebicides (correct)
  • Tissue amoebicides
  • Alkaloids

Which class of drugs is commonly used for the treatment of intestinal and extraintestinal amoebiasis?

  • Amides
  • Nitroimidazoles (correct)
  • 8-Hydroxyquinolines
  • Antibiotics

Which drug is specifically used for the treatment of extraintestinal amoebiasis?

<p>Chloroquine (C)</p> Signup and view all the answers

Which type of amoebicides attain high concentration in blood and tissues following oral or parenteral administration?

<p>Tissue amoebicides (A)</p> Signup and view all the answers

Which type of microorganisms is metronidazole highly effective against?

<p>Anaerobic bacteria (C)</p> Signup and view all the answers

What is the mechanism of action of metronidazole?

<p>Inhibition of nucleic acid synthesis (A)</p> Signup and view all the answers

Which protozoa is metronidazole effective against?

<p>Trichomonas vaginalis (C)</p> Signup and view all the answers

In the presence of oxygen, metronidazole is ineffective against which type of microorganisms?

<p>Aerobic bacteria (C)</p> Signup and view all the answers

Which body fluids can achieve therapeutic levels of metronidazole?

<p>Bile and breast milk (B)</p> Signup and view all the answers

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