Amino Acids Net Charge and Zwitterions

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Questions and Answers

Which of the following statements about amino acids is correct?

  • Amino acids always have a zero net charge.
  • Amino acids can have a positive, negative, or zero net charge. (correct)
  • Amino acids can only have a positive or negative net charge.
  • Amino acids can only have a positive net charge.

What is the term used to describe an amino acid with an equal number of positively and negatively charged groups?

  • Neutral
  • Isoelectric
  • Zwitterion (correct)
  • Polar

What is the isoelectric pH (pI) for the amino acid aspartic acid?

  • pI = 9.2
  • pI = 5.0
  • pI = 7.4
  • pI = 3.9 (correct)

Which of the following statements about the solubility of amino acids is correct?

<p>Amino acids with a positive or negative net charge are more soluble than those with a zero net charge. (B)</p> Signup and view all the answers

What is the primary structural feature that determines the properties of amino acids?

<p>The side chain (R-group) (B)</p> Signup and view all the answers

What is the purpose of the non-α peptide bond in the structure of glutathione?

<p>To link the glutamic acid and cysteine residues (D)</p> Signup and view all the answers

What is the primary function of amino acids in the body?

<p>Structural components of proteins (C)</p> Signup and view all the answers

What is the charge on an amino acid at its isoelectric point (pI)?

<p>Zero (B)</p> Signup and view all the answers

Which of the following best describes the zwitterionic nature of amino acids?

<p>Amino acids have both positively and negatively charged groups (C)</p> Signup and view all the answers

Which type of amino acid has a non-polar, hydrophobic side chain?

<p>Alanine (D)</p> Signup and view all the answers

What is the purpose of the R-group in amino acid structure?

<p>To provide the amino acid with its unique chemical properties (D)</p> Signup and view all the answers

Which of the following best describes the peptide bond in a polypeptide chain?

<p>It is a partial double bond with limited rotation (C)</p> Signup and view all the answers

What property of selenocysteine makes it a better nucleophile than cysteine at or below pH 7.4?

<p>Selenocysteine has a lower pKa than cysteine, making it more reactive at physiological pH. (C)</p> Signup and view all the answers

Which of the following is an example of a nonprotein L-$\alpha$-amino acid?

<p>$\beta$-Alanine (A)</p> Signup and view all the answers

What is the primary reason certain plant L-$\alpha$-amino acids can adversely impact human health?

<p>They have structural modifications that make them toxic. (D)</p> Signup and view all the answers

What is the net charge of an amino acid at its isoelectric point?

<p>Zero (D)</p> Signup and view all the answers

Which of the following is a characteristic of the zwitterionic form of an amino acid?

<p>The carboxyl group is deprotonated and the amino group is protonated. (D)</p> Signup and view all the answers

What is the purpose of the resonance hybrids shown in Figure 3-4 for the R-groups of histidine and arginine?

<p>To allow the R-groups to act as both acids and bases. (C)</p> Signup and view all the answers

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