Amino Acid Transamination Reactions Quiz
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Questions and Answers

What is the purpose of transamination?

  • To collect amino groups to form glutamate (correct)
  • To produce NH3
  • To form oxaloacetate
  • To break down glutamate
  • Which enzyme is responsible for the formation of ammonia from glutamate?

  • Pyridoxal phosphate
  • Serine deaminase
  • Alanine transaminase
  • Glutamate dehydrogenase (correct)
  • Which vitamin derivative is the prosthetic group of all transaminases?

  • Vitamin B6 (Pyridoxine) (correct)
  • Vitamin B12 (Cobalamin)
  • Vitamin C
  • Vitamin D
  • Where does the oxidative deamination of glutamate occur?

    <p>Mitochondria</p> Signup and view all the answers

    Which of the following is a product of the reaction: Ala + KG → Pyruvate + Glutamate?

    <p>Pyruvate + Glutamate</p> Signup and view all the answers

    Why is it important to prevent NH4+ buildup in tissues?

    <p>To ensure proper urea formation in the liver</p> Signup and view all the answers

    What is the main function of transaminases or amino transferases?

    <p>Synthesis of non-essential amino acids</p> Signup and view all the answers

    During transamination, what happens to the α-amino group of an amino acid?

    <p>It is enzymatically removed and transferred to an α-carbon atom of an α-keto acid</p> Signup and view all the answers

    Which process involves the amination of α-ketoglutarate?

    <p>Transamination</p> Signup and view all the answers

    What is the final excretory group formed when amino groups are not re-used?

    <p>Urea</p> Signup and view all the answers

    Which enzyme promotes the removal of the amino group during transamination?

    <p>Alanine transaminase</p> Signup and view all the answers

    What happens to the α-keto acid during transamination?

    <p>It forms an α-amino acid analog</p> Signup and view all the answers

    What is the primary function of transaminases in amino acid metabolism?

    <p>To funnel amino groups from various compounds</p> Signup and view all the answers

    Which enzyme converts alanine to pyruvate?

    <p>Alanine Transaminase</p> Signup and view all the answers

    In amino acid metabolism, where do most amino groups get funneled into?

    <p>Formation of glutamate or aspartate</p> Signup and view all the answers

    Which enzyme must produce glutamine in order to lead to the urea cycle?

    <p>Glutamine Synthetase</p> Signup and view all the answers

    What is the final product of the reaction catalyzed by Glutamate Dehydrogenase?

    <p>Glutamate</p> Signup and view all the answers

    Which compound is a common amino group donor to the urea cycle?

    <p>Aspartate</p> Signup and view all the answers

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