Podcast
Questions and Answers
Which medication should be taken with breakfast and dinner?
Which medication should be taken with breakfast and dinner?
- Galantamine solution
- Galantamine IR (correct)
- Exelon capsules
- Galantamine ER
What is the mechanism of action of memantine?
What is the mechanism of action of memantine?
- Blocks NMDA receptors (correct)
- Inhibits glutamate binding
- Increases abnormal neuron activation
- Decreases abnormal neuron activation
Which formulation of memantine can be mixed with liquid?
Which formulation of memantine can be mixed with liquid?
- Namzaric
- Tablet
- Capsule
- Oral solution (correct)
What is the starting dose of memantine IR in the combination product Namzaric?
What is the starting dose of memantine IR in the combination product Namzaric?
What is the maximum daily dose of memantine for patients with CrCI < 30 ml/min?
What is the maximum daily dose of memantine for patients with CrCI < 30 ml/min?
What are the common side effects of memantine?
What are the common side effects of memantine?
How should the ER capsule and Namzaric be taken?
How should the ER capsule and Namzaric be taken?
What is the brand name of the combination product containing memantine and donepezil?
What is the brand name of the combination product containing memantine and donepezil?
Which medication should be switched to Namzaric if stable on donepezil 10 mg?
Which medication should be switched to Namzaric if stable on donepezil 10 mg?
What does the brand name NaMenDA indicate about the medication?
What does the brand name NaMenDA indicate about the medication?
Which enzyme do acetylcholinesterase inhibitors inhibit?
Which enzyme do acetylcholinesterase inhibitors inhibit?
Which drug is a combination of Donepezil and memantine?
Which drug is a combination of Donepezil and memantine?
What is the dosing recommendation for Donepezil + memantine (Namzaric) in moderate-to-severe disease?
What is the dosing recommendation for Donepezil + memantine (Namzaric) in moderate-to-severe disease?
What is the dosing recommendation for Rivastigmine (Exelon) in capsule form?
What is the dosing recommendation for Rivastigmine (Exelon) in capsule form?
What is the maximum patch dose for Rivastigmine (Exelon) in patients with hepatic impairment?
What is the maximum patch dose for Rivastigmine (Exelon) in patients with hepatic impairment?
What is the initial dosing recommendation for Galantamine (Razadyne, Razadyne ER) in IR tablet or solution form?
What is the initial dosing recommendation for Galantamine (Razadyne, Razadyne ER) in IR tablet or solution form?
What should be avoided in patients with severe hepatic or renal impairment when using Galantamine (Razadyne, Razadyne ER)?
What should be avoided in patients with severe hepatic or renal impairment when using Galantamine (Razadyne, Razadyne ER)?
What are the warnings associated with acetylcholinesterase inhibitors?
What are the warnings associated with acetylcholinesterase inhibitors?
What are the common side effects of acetylcholinesterase inhibitors?
What are the common side effects of acetylcholinesterase inhibitors?
Which acetylcholinesterase inhibitor is dosed QHS to help decrease nausea?
Which acetylcholinesterase inhibitor is dosed QHS to help decrease nausea?
Acetylcholinesterase inhibitors increase the breakdown of acetylcholine in the brain.
Acetylcholinesterase inhibitors increase the breakdown of acetylcholine in the brain.
Galantamine is available in tablet, capsule, and solution forms.
Galantamine is available in tablet, capsule, and solution forms.
Donepezil is the only acetylcholinesterase inhibitor that should be taken with food.
Donepezil is the only acetylcholinesterase inhibitor that should be taken with food.
Rivastigmine can be administered through a patch or a capsule.
Rivastigmine can be administered through a patch or a capsule.
The starting dose of Donepezil + memantine (Namzaric) is 5 mg once daily.
The starting dose of Donepezil + memantine (Namzaric) is 5 mg once daily.
Patients with severe hepatic or renal impairment should avoid using Galantamine.
Patients with severe hepatic or renal impairment should avoid using Galantamine.
Cardiac effects, including bradycardia and syncope, are common side effects of acetylcholinesterase inhibitors.
Cardiac effects, including bradycardia and syncope, are common side effects of acetylcholinesterase inhibitors.
Nausea and diarrhea are common side effects of Donepezil.
Nausea and diarrhea are common side effects of Donepezil.
Exelon patch should be applied to the same site for 14 days before rotating to a new site.
Exelon patch should be applied to the same site for 14 days before rotating to a new site.
Memantine is an acetylcholinesterase inhibitor.
Memantine is an acetylcholinesterase inhibitor.
True or false: Memantine blocks NMDA receptors, which inhibits glutamate from binding and decreases abnormal neuron activation?
True or false: Memantine blocks NMDA receptors, which inhibits glutamate from binding and decreases abnormal neuron activation?
True or false: Galantamine IR should be taken with breakfast and dinner, while galantamine ER should be taken with breakfast?
True or false: Galantamine IR should be taken with breakfast and dinner, while galantamine ER should be taken with breakfast?
True or false: Galantamine solution can be mixed with liquid and should be consumed immediately?
True or false: Galantamine solution can be mixed with liquid and should be consumed immediately?
True or false: If stable on donepezil 10 mg, it is recommended to switch to Namzaric (memantine 7 mg/donepezil 10 mg QHS) and titrate weekly?
True or false: If stable on donepezil 10 mg, it is recommended to switch to Namzaric (memantine 7 mg/donepezil 10 mg QHS) and titrate weekly?
True or false: Memantine is available in tablet, capsule, and oral solution forms?
True or false: Memantine is available in tablet, capsule, and oral solution forms?
True or false: It is possible to switch from memantine IR 10 mg BID to memantine ER 28 mg daily?
True or false: It is possible to switch from memantine IR 10 mg BID to memantine ER 28 mg daily?
True or false: The maximum dose of memantine for patients with CrCI < 30 ml/min is 5 mg PO BID (IR) or 14 mg PO daily (ER)?
True or false: The maximum dose of memantine for patients with CrCI < 30 ml/min is 5 mg PO BID (IR) or 14 mg PO daily (ER)?
True or false: Caution should be exercised when using memantine with drugs or conditions that increase urine pH, as it may decrease clearance of memantine?
True or false: Caution should be exercised when using memantine with drugs or conditions that increase urine pH, as it may decrease clearance of memantine?
True or false: Memantine is generally well-tolerated but can cause side effects such as dizziness, confusion, headache, constipation, and syncope?
True or false: Memantine is generally well-tolerated but can cause side effects such as dizziness, confusion, headache, constipation, and syncope?
True or false: ER capsules and Namzaric should not be crushed or chewed, but capsules can be opened and sprinkled on applesauce?
True or false: ER capsules and Namzaric should not be crushed or chewed, but capsules can be opened and sprinkled on applesauce?
What is the mechanism of action of memantine?
What is the mechanism of action of memantine?
What is the dosing recommendation for Galantamine (Razadyne, Razadyne ER) in IR tablet or solution form?
What is the dosing recommendation for Galantamine (Razadyne, Razadyne ER) in IR tablet or solution form?
What is the maximum daily dose of memantine for patients with CrCI < 30 ml/min?
What is the maximum daily dose of memantine for patients with CrCI < 30 ml/min?
What is the brand name of the combination product containing memantine and donepezil?
What is the brand name of the combination product containing memantine and donepezil?
What are the warnings associated with acetylcholinesterase inhibitors?
What are the warnings associated with acetylcholinesterase inhibitors?
True or false: Galantamine solution can be mixed with liquid and should be consumed immediately?
True or false: Galantamine solution can be mixed with liquid and should be consumed immediately?
True or false: If stable on donepezil 10 mg, it is recommended to switch to Namzaric (memantine 7 mg/donepezil 10 mg QHS) and titrate weekly?
True or false: If stable on donepezil 10 mg, it is recommended to switch to Namzaric (memantine 7 mg/donepezil 10 mg QHS) and titrate weekly?
What is the starting dose of memantine IR in the combination product Namzaric?
What is the starting dose of memantine IR in the combination product Namzaric?
True or false: ER capsules and Namzaric should not be crushed or chewed, but capsules can be opened and sprinkled on applesauce?
True or false: ER capsules and Namzaric should not be crushed or chewed, but capsules can be opened and sprinkled on applesauce?
True or false: Galantamine IR should be taken with breakfast and dinner, while galantamine ER should be taken with breakfast?
True or false: Galantamine IR should be taken with breakfast and dinner, while galantamine ER should be taken with breakfast?
What is the mechanism of action of acetylcholinesterase inhibitors?
What is the mechanism of action of acetylcholinesterase inhibitors?
What are the generic and brand names of the acetylcholinesterase inhibitor that is a combination of donepezil and memantine?
What are the generic and brand names of the acetylcholinesterase inhibitor that is a combination of donepezil and memantine?
What is the dosing recommendation for Rivastigmine (Exelon) in capsule form?
What is the dosing recommendation for Rivastigmine (Exelon) in capsule form?
What are the warnings associated with acetylcholinesterase inhibitors?
What are the warnings associated with acetylcholinesterase inhibitors?
What are the common side effects of acetylcholinesterase inhibitors?
What are the common side effects of acetylcholinesterase inhibitors?
How should the Exelon patch be used?
How should the Exelon patch be used?
What is the starting dose of Galantamine (Razadyne, Razadyne ER) in immediate-release tablet or solution form?
What is the starting dose of Galantamine (Razadyne, Razadyne ER) in immediate-release tablet or solution form?
What should be avoided in patients with severe hepatic or renal impairment when using Galantamine (Razadyne, Razadyne ER)?
What should be avoided in patients with severe hepatic or renal impairment when using Galantamine (Razadyne, Razadyne ER)?
What is the starting dose of Donepezil (Aricept) orally disintegrating tablet (ODT)?
What is the starting dose of Donepezil (Aricept) orally disintegrating tablet (ODT)?
What is the maximum patch dose of Rivastigmine (Exelon) in patients with hepatic impairment?
What is the maximum patch dose of Rivastigmine (Exelon) in patients with hepatic impairment?
Match the following medications with their administration instructions:
Match the following medications with their administration instructions:
Match the following medications with their forms:
Match the following medications with their forms:
Match the following medications with their maximum dose for CrCI < 30 ml/min:
Match the following medications with their maximum dose for CrCI < 30 ml/min:
Match the following medications with their warnings:
Match the following medications with their warnings:
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Match the following medications with their side effects:
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Match the following medications with their notes on administration:
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Match the following medications with their mechanism of action:
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Match the following brand names with their embedded drug name:
Match the following medications with their instructions for switching forms:
Match the following medications with their instructions for switching forms:
Match the following medications with their instructions for switching to a combination product:
Match the following medications with their instructions for switching to a combination product:
Match the following acetylcholinesterase inhibitors with their brand names:
Match the following acetylcholinesterase inhibitors with their brand names:
Match the following acetylcholinesterase inhibitors with their initial dosing recommendations:
Match the following acetylcholinesterase inhibitors with their initial dosing recommendations:
Match the following acetylcholinesterase inhibitors with their maximum dosing recommendations for patients with hepatic impairment:
Match the following acetylcholinesterase inhibitors with their maximum dosing recommendations for patients with hepatic impairment:
Match the following acetylcholinesterase inhibitors with the conditions they are used to treat:
Match the following acetylcholinesterase inhibitors with the conditions they are used to treat:
Match the following acetylcholinesterase inhibitors with their common side effects:
Match the following acetylcholinesterase inhibitors with their common side effects:
Match the following acetylcholinesterase inhibitors with their administration forms:
Match the following acetylcholinesterase inhibitors with their administration forms:
Match the acetylcholinesterase inhibitors with their warnings:
Match the acetylcholinesterase inhibitors with their warnings:
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Match the acetylcholinesterase inhibitors with their mechanisms of action:
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Match the acetylcholinesterase inhibitors with their dosing schedules:
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Match the acetylcholinesterase inhibitors with their notes about administration:
Which of the following drugs can potentially reduce the efficacy of acetylcholinesterase inhibitors?
Which of the following drugs can potentially reduce the efficacy of acetylcholinesterase inhibitors?
Which of the following drugs should be used with caution due to the risk of GI bleeding when taken with acetylcholinesterase inhibitors?
Which of the following drugs should be used with caution due to the risk of GI bleeding when taken with acetylcholinesterase inhibitors?
Which of the following drugs should be used with caution due to their potential to cause dizziness when taken with acetylcholinesterase inhibitors?
Which of the following drugs should be used with caution due to their potential to cause dizziness when taken with acetylcholinesterase inhibitors?
True or false: Acetylcholinesterase inhibitors can reduce the efficacy of drugs with anticholinergic effects?
True or false: Acetylcholinesterase inhibitors can reduce the efficacy of drugs with anticholinergic effects?
True or false: NSAIDs should be used cautiously with acetylcholinesterase inhibitors due to the risk of GI bleeding?
True or false: NSAIDs should be used cautiously with acetylcholinesterase inhibitors due to the risk of GI bleeding?
True or false: Discontinuing incontinence drugs is recommended if there is no benefit?
True or false: Discontinuing incontinence drugs is recommended if there is no benefit?
Match the following drugs with their interactions when used with acetylcholinesterase inhibitors:
Match the following drugs with their interactions when used with acetylcholinesterase inhibitors: