Alzheimer's Drug Treatment Overview

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Questions and Answers

Which medication is considered the mainstay of treatment for Alzheimer's disease?

  • Namzaric
  • Donepezil (correct)
  • Memantine
  • Sertraline

What is the purpose of using acetylcholinesterase inhibitors in Alzheimer's disease treatment?

  • To provide noticeable improvement
  • To slow down disease progression (correct)
  • To treat depression and anxiety
  • To cure the disease

When should acetylcholinesterase inhibitors be discontinued in Alzheimer's disease treatment?

  • If there is no improvement
  • If the disease has advanced to a certain point (correct)
  • If the patient experiences noticeable deterioration
  • If side effects are intolerable

Which of the following is a step in the drug treatment algorithm for Alzheimer's Disease?

<p>Discontinue drugs that can worsen dementia (D)</p> Signup and view all the answers

What is the recommended treatment for mild-moderate Alzheimer's Disease?

<p>Start an acetylcholinesterase inhibitor (C)</p> Signup and view all the answers

What is the additional treatment note mentioned in the text?

<p>All of the above (D)</p> Signup and view all the answers

True or false: Acetylcholinesterase inhibitors are used alone in the early stages of Alzheimer's disease treatment?

<p>False (B)</p> Signup and view all the answers

True or false: Acetylcholinesterase inhibitors can cause side effects such as nausea, diarrhea, and dizziness?

<p>True (A)</p> Signup and view all the answers

True or false: Memantine is approved for use alone or with donepezil for mild disease?

<p>False (B)</p> Signup and view all the answers

True or false: Antipsychotics are commonly prescribed for the treatment of Alzheimer's disease.

<p>False (B)</p> Signup and view all the answers

True or false: Combination treatment with an acetylcholinesterase inhibitor and memantine is more effective in delaying the progression of Alzheimer's disease than monotherapy.

<p>True (A)</p> Signup and view all the answers

True or false: It is recommended to titrate medications quickly when treating Alzheimer's disease.

<p>False (B)</p> Signup and view all the answers

What are the mainstay drugs used in the treatment of Alzheimer's disease?

<p>Acetylcholinesterase inhibitors (e.g., donepezil)</p> Signup and view all the answers

What are the potential side effects of acetylcholinesterase inhibitors?

<p>Nausea, diarrhea, dizziness</p> Signup and view all the answers

When can acetylcholinesterase inhibitors be discontinued in Alzheimer's disease treatment?

<p>If there is no improvement or if side effects are intolerable</p> Signup and view all the answers

What are the steps of the drug treatment algorithm for Alzheimer's Disease?

<p>Step 1: Non-Drug Interventions to Keep the Brain Healthy, Step 2: Drug Treatment: Mild-Moderate Alzheimer's Disease, Step 3: Disease Worsens</p> Signup and view all the answers

What are the potential side effects of acetylcholinesterase inhibitors?

<p>Nausea, diarrhea, and dizziness</p> Signup and view all the answers

What is the purpose of using antipsychotics in Alzheimer's disease treatment?

<p>Antipsychotics are used off-label for delusions and agitation</p> Signup and view all the answers

Match the following medications with their usage in Alzheimer's disease treatment:

<p>Acetylcholinesterase inhibitors = Mainstay of treatment, used alone or with memantine Memantine (Namenda) = Used alone or with donepezil for moderate-to-severe disease Namzaric = Combination of donepezil and memantine Antidepressants (e.g., sertraline, citalopram, escitalopram) = Used to treat related depression and anxiety</p> Signup and view all the answers

Match the following medications with their associated side effects or administration instructions:

<p>Acetylcholinesterase inhibitors = Can cause nausea, diarrhea, dizziness and should be monitored for both improvement and side effects Donepezil = Taken at bedtime to reduce nausea Memantine (Namenda) = Approved for use alone or with donepezil for moderate-to-severe disease Antidepressants (e.g., sertraline, citalopram, escitalopram) = Used to treat related depression and anxiety</p> Signup and view all the answers

Match the following statements with the corresponding medications in Alzheimer's disease:

<p>Patients stabilized on this medication can be switched to Namzaric = Donepezil This is a combination of donepezil and memantine = Namzaric These are used alone or with memantine in more advanced stages of the disease = Acetylcholinesterase inhibitors These can be used to treat related depression and anxiety = Antidepressants (e.g., sertraline, citalopram, escitalopram)</p> Signup and view all the answers

Match the following steps in the drug treatment algorithm for dementia with their corresponding actions:

<p>Step 1 = Non-drug interventions like exercise, healthy diet, controlling blood glucose, blood pressure and cholesterol, and brain-stimulating activities Step 2 = Drug treatment starting with an acetylcholinesterase Inhibitor for mild-moderate Alzheimer's Disease, and adding memantine for moderate-severe Alzheimer's Disease Step 3 = Use combination treatment of acetylcholinesterase inhibitor + memantine when disease worsens</p> Signup and view all the answers

Match the following Alzheimer's disease stages with their corresponding drug treatment:

<p>Mild-Moderate = Start an acetylcholinesterase Inhibitor (donepezil, rivastigmine, galantamine) Moderate-Severe = Start an acetylcholinesterase Inhibitor (donepezil, rivastigmine, galantamine) and/or memantine</p> Signup and view all the answers

Match the following medications with their use in Alzheimer's disease treatment:

<p>Acetylcholinesterase inhibitors = Mainstay of treatment, used in all stages of the disease Memantine = Used alone or in combination with acetylcholinesterase inhibitors, more likely to delay the progression of disease than monotherapy Antipsychotics = Used off-label for delusions and agitation, but with an increased risk of death in elderly patients</p> Signup and view all the answers

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