Alzheimer's Disease Quiz
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Questions and Answers

What percentage of all Alzheimer's disease cases does familial AD account for?

  • Less than 2% (correct)
  • 10%
  • 20%
  • 5%

    • Which neuropathologic and biochemical changes interfere with neurotransmission in Alzheimer's disease?

  • Amyloid protein and amyloid precursor protein
  • Neurofibrillary tangles and senile plaques (correct)
  • Cerebral cortex damage and decreased brain size
  • Enzyme activity and neurotransmitter levels

    • Which neurotransmitter is principally affected by Alzheimer's disease at the cellular level?

  • Dopamine
  • GABA
  • Acetylcholine (correct)
  • Serotonin

    • What are the early clinical manifestations of Alzheimer's disease characterized by?

    <p>Forgetfulness and subtle memory loss</p> Signup and view all the answers

    What do patients with advanced Alzheimer's disease have difficulty with?

    <p>Operating simple appliances and handling money</p> Signup and view all the answers

    What is the terminal stage of Alzheimer's disease characterized by?

    <p>Patients are usually immobile and require total care</p> Signup and view all the answers

    What are the genetic differences in early- and late-onset forms of Alzheimer's disease related to?

    <p>Overall risk and age at onset</p> Signup and view all the answers

    What are the biochemical changes in Alzheimer's disease related to?

    <p>Decreased enzyme activity in producing acetylcholine</p> Signup and view all the answers

    What may be included in the familial component of Alzheimer's disease?

    <p>Both environmental triggers and genetic determinants</p> Signup and view all the answers

    What is the neuronal damage in Alzheimer's disease primarily located in?

    <p>Cerebral cortex</p> Signup and view all the answers

    What are the specific changes found in the normal brain tissue of nonsymptomatic older adults related to?

    <p>Neurofibrillary tangles and senile or neuritic plaques</p> Signup and view all the answers

    What do scientists focus on in the study of complex neurodegenerative diseases such as Alzheimer's disease?

    <p>Both a and b</p> Signup and view all the answers

    What is the sixth leading cause of death in the United States?

    <p>Alzheimer's Disease</p> Signup and view all the answers

    At what age does Alzheimer's Disease become the fifth leading cause of death in the United States?

    <p>65 years and older</p> Signup and view all the answers

    What is the estimated number of Americans projected to have Alzheimer's Disease by 2050?

    <p>13.8 million</p> Signup and view all the answers

    At what age can Alzheimer's Disease occur, although less commonly?

    <p>40 years</p> Signup and view all the answers

    What is the sixth leading cause of death in the United States?

    <p>Alzheimer Disease (AD)</p> Signup and view all the answers

    At what age does AD become the fifth leading cause of death in the United States?

    <p>65 years and older</p> Signup and view all the answers

    What is the estimated number of Americans projected to have AD by 2050?

    <p>13.8 million</p> Signup and view all the answers

    What are some factors that may determine whether a person suffers from AD?

    <p>Genetics, neurotransmitter changes, vascular abnormalities</p> Signup and view all the answers

    What is the estimated percentage of all Alzheimer's disease cases accounted for by familial AD?

    <p>Less than 2%</p> Signup and view all the answers

    In which part of the brain does the neuronal damage primarily occur in Alzheimer's disease?

    <p>Cerebral cortex</p> Signup and view all the answers

    Which neurotransmitter is principally affected by Alzheimer's disease at the cellular level?

    <p>Acetylcholine</p> Signup and view all the answers

    What is the early stage of Alzheimer's disease characterized by?

    <p>Forgetfulness and subtle memory loss</p> Signup and view all the answers

    What are the specific changes found in the normal brain tissue of nonsymptomatic older adults related to Alzheimer's disease?

    <p>Neurofibrillary tangles</p> Signup and view all the answers

    What is the terminal stage of Alzheimer's disease characterized by?

    <p>Patients are usually immobile and require total care</p> Signup and view all the answers

    What is the estimated number of Americans projected to have Alzheimer's Disease by 2050?

    <p>13.8 million</p> Signup and view all the answers

    What may be included in the familial component of Alzheimer's disease?

    <p>Both genetic mutations and environmental triggers</p> Signup and view all the answers

    What are the biochemical changes in Alzheimer's disease related to?

    <p>Neurotransmission interference</p> Signup and view all the answers

    What are researchers studying in complex neurodegenerative diseases such as Alzheimer's disease?

    <p>Both a and b</p> Signup and view all the answers

    What are the genetic differences in early- and late-onset forms of Alzheimer's disease related to?

    <p>The age at which the disease begins</p> Signup and view all the answers

    At what age can Alzheimer's Disease occur, although less commonly?

    <p>Middle-aged adults</p> Signup and view all the answers

    What is the estimated number of Americans projected to have Alzheimer's Disease by 2050?

    <p>13.8 million</p> Signup and view all the answers

    At what age can Alzheimer's Disease occur, although less commonly?

    <p>40 years</p> Signup and view all the answers

    What is the most significant risk factor for Alzheimer's Disease?

    <p>Increasing age</p> Signup and view all the answers

    What can Alzheimer's Disease be classified into?

    <p>Familial or early-onset AD and sporadic or late-onset AD</p> Signup and view all the answers

    What is the sixth leading cause of death in the United States?

    <p>Alzheimer's Disease</p> Signup and view all the answers

    What is the fifth leading cause of death for adults 65 years of age and older in the United States?

    <p>Alzheimer's Disease</p> Signup and view all the answers

    What is the prevalence of Alzheimer's Disease among those 85 years and older?

    <p>Affects as many as half</p> Signup and view all the answers

    What is the primary affected age group for Alzheimer's Disease?

    <p>65 years and older</p> Signup and view all the answers

    What environmental, dietary, and inflammatory factors may determine whether a person suffers from Alzheimer's Disease?

    <p>Stress hormones</p> Signup and view all the answers

    What may be included in the familial component of Alzheimer's Disease?

    <p>Genetics</p> Signup and view all the answers

    What are the early clinical manifestations of Alzheimer's Disease characterized by?

    <p>Gradual losses of cognitive function and disturbances in behavior and affect</p> Signup and view all the answers

    What is the terminal stage of Alzheimer's Disease characterized by?

    <p>Complete loss of cognitive and physical function</p> Signup and view all the answers

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