Alzheimer's Disease Quiz
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Questions and Answers

What percentage of all Alzheimer's disease cases does familial AD account for?

  • Less than 2% (correct)
  • 10%
  • 20%
  • 5%
  • Which neuropathologic and biochemical changes interfere with neurotransmission in Alzheimer's disease?

  • Amyloid protein and amyloid precursor protein
  • Neurofibrillary tangles and senile plaques (correct)
  • Cerebral cortex damage and decreased brain size
  • Enzyme activity and neurotransmitter levels
  • Which neurotransmitter is principally affected by Alzheimer's disease at the cellular level?

  • Dopamine
  • GABA
  • Acetylcholine (correct)
  • Serotonin
  • What are the early clinical manifestations of Alzheimer's disease characterized by?

    <p>Forgetfulness and subtle memory loss (C)</p> Signup and view all the answers

    What do patients with advanced Alzheimer's disease have difficulty with?

    <p>Operating simple appliances and handling money (B)</p> Signup and view all the answers

    What is the terminal stage of Alzheimer's disease characterized by?

    <p>Patients are usually immobile and require total care (A)</p> Signup and view all the answers

    What are the genetic differences in early- and late-onset forms of Alzheimer's disease related to?

    <p>Overall risk and age at onset (D)</p> Signup and view all the answers

    What are the biochemical changes in Alzheimer's disease related to?

    <p>Decreased enzyme activity in producing acetylcholine (D)</p> Signup and view all the answers

    What may be included in the familial component of Alzheimer's disease?

    <p>Both environmental triggers and genetic determinants (D)</p> Signup and view all the answers

    What is the neuronal damage in Alzheimer's disease primarily located in?

    <p>Cerebral cortex (D)</p> Signup and view all the answers

    What are the specific changes found in the normal brain tissue of nonsymptomatic older adults related to?

    <p>Neurofibrillary tangles and senile or neuritic plaques (A)</p> Signup and view all the answers

    What do scientists focus on in the study of complex neurodegenerative diseases such as Alzheimer's disease?

    <p>Both a and b (C)</p> Signup and view all the answers

    What is the sixth leading cause of death in the United States?

    <p>Alzheimer's Disease (D)</p> Signup and view all the answers

    At what age does Alzheimer's Disease become the fifth leading cause of death in the United States?

    <p>65 years and older (C)</p> Signup and view all the answers

    What is the estimated number of Americans projected to have Alzheimer's Disease by 2050?

    <p>13.8 million (D)</p> Signup and view all the answers

    At what age can Alzheimer's Disease occur, although less commonly?

    <p>40 years (C)</p> Signup and view all the answers

    What is the sixth leading cause of death in the United States?

    <p>Alzheimer Disease (AD) (D)</p> Signup and view all the answers

    At what age does AD become the fifth leading cause of death in the United States?

    <p>65 years and older (B)</p> Signup and view all the answers

    What is the estimated number of Americans projected to have AD by 2050?

    <p>13.8 million (B)</p> Signup and view all the answers

    What are some factors that may determine whether a person suffers from AD?

    <p>Genetics, neurotransmitter changes, vascular abnormalities (D)</p> Signup and view all the answers

    What is the estimated percentage of all Alzheimer's disease cases accounted for by familial AD?

    <p>Less than 2% (D)</p> Signup and view all the answers

    In which part of the brain does the neuronal damage primarily occur in Alzheimer's disease?

    <p>Cerebral cortex (D)</p> Signup and view all the answers

    Which neurotransmitter is principally affected by Alzheimer's disease at the cellular level?

    <p>Acetylcholine (D)</p> Signup and view all the answers

    What is the early stage of Alzheimer's disease characterized by?

    <p>Forgetfulness and subtle memory loss (A)</p> Signup and view all the answers

    What are the specific changes found in the normal brain tissue of nonsymptomatic older adults related to Alzheimer's disease?

    <p>Neurofibrillary tangles (B)</p> Signup and view all the answers

    What is the terminal stage of Alzheimer's disease characterized by?

    <p>Patients are usually immobile and require total care (A)</p> Signup and view all the answers

    What is the estimated number of Americans projected to have Alzheimer's Disease by 2050?

    <p>13.8 million (C)</p> Signup and view all the answers

    What may be included in the familial component of Alzheimer's disease?

    <p>Both genetic mutations and environmental triggers (B)</p> Signup and view all the answers

    What are the biochemical changes in Alzheimer's disease related to?

    <p>Neurotransmission interference (A)</p> Signup and view all the answers

    What are researchers studying in complex neurodegenerative diseases such as Alzheimer's disease?

    <p>Both a and b (D)</p> Signup and view all the answers

    What are the genetic differences in early- and late-onset forms of Alzheimer's disease related to?

    <p>The age at which the disease begins (A)</p> Signup and view all the answers

    At what age can Alzheimer's Disease occur, although less commonly?

    <p>Middle-aged adults (C)</p> Signup and view all the answers

    What is the estimated number of Americans projected to have Alzheimer's Disease by 2050?

    <p>13.8 million (C)</p> Signup and view all the answers

    At what age can Alzheimer's Disease occur, although less commonly?

    <p>40 years (D)</p> Signup and view all the answers

    What is the most significant risk factor for Alzheimer's Disease?

    <p>Increasing age (B)</p> Signup and view all the answers

    What can Alzheimer's Disease be classified into?

    <p>Familial or early-onset AD and sporadic or late-onset AD (A)</p> Signup and view all the answers

    What is the sixth leading cause of death in the United States?

    <p>Alzheimer's Disease (A)</p> Signup and view all the answers

    What is the fifth leading cause of death for adults 65 years of age and older in the United States?

    <p>Alzheimer's Disease (A)</p> Signup and view all the answers

    What is the prevalence of Alzheimer's Disease among those 85 years and older?

    <p>Affects as many as half (C)</p> Signup and view all the answers

    What is the primary affected age group for Alzheimer's Disease?

    <p>65 years and older (A)</p> Signup and view all the answers

    What environmental, dietary, and inflammatory factors may determine whether a person suffers from Alzheimer's Disease?

    <p>Stress hormones (D)</p> Signup and view all the answers

    What may be included in the familial component of Alzheimer's Disease?

    <p>Genetics (D)</p> Signup and view all the answers

    What are the early clinical manifestations of Alzheimer's Disease characterized by?

    <p>Gradual losses of cognitive function and disturbances in behavior and affect (A)</p> Signup and view all the answers

    What is the terminal stage of Alzheimer's Disease characterized by?

    <p>Complete loss of cognitive and physical function (A)</p> Signup and view all the answers

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