18 Questions
What is the primary characteristic of Amyotrophic Lateral Sclerosis?
Degeneration of upper and lower motor neurons
What has been observed in early-stage Amyotrophic Lateral Sclerosis?
Increased cortical connectivity
What is the focus of studies using MRI in Amyotrophic Lateral Sclerosis?
Finding neural biomarkers
Which of the following is NOT a characteristic of Amyotrophic Lateral Sclerosis?
Progressive loss of dopamine in the basal nuclei
What is the term for the degeneration of upper and lower motor neurons in Amyotrophic Lateral Sclerosis?
ALS
Which neuroimaging technique is used to study Amyotrophic Lateral Sclerosis?
MRI
What is a characteristic of Amyotrophic Lateral Sclerosis (ALS) in its early stages?
Increased cortical connectivity
What is the purpose of neurostimulation in the context of ALS?
To purposefully modulate the nervous system's activity
What is the primary difference between DBS and tDCS?
DBS is invasive, while tDCS is non-invasive
What is the effect of voltage pulses applied by neurostimulation on neurons?
They cause a depolarization or hyperpolarization of neurons
What is the limitation of the current used in tDCS?
It is not strong enough to trigger an action potential in a neuron
How many studies have tried to find a neural biomarker using MRI for ALS?
More than 100 studies
What is a common complication of dysarthria?
Social difficulty and depression
What is the primary location of damage in Ataxic dysarthria?
Cerebellum
What is the characteristic of Apraxia of speech that is not shared with Dysarthria?
Difficulty with planning and coordinating speech movements
Which of the following is NOT a symptom of Flaccid dysarthria?
Spasticity
What is the term for the condition of weakness of muscles or difficulty in controlling them?
Dysarthria
Which of the following neurological disorders is associated with Dysarthria?
All of the above
This quiz covers the latest research on finding neural biomarkers for ALS, including the use of MRI and MEG signals. It also explores the concept of early compensation mechanisms in ALS and the potential of neurostimulation. Test your knowledge of this complex and fascinating topic!
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