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Questions and Answers
What is the purpose of corticosteroids in the treatment of allergic reactions?
What is the purpose of corticosteroids in the treatment of allergic reactions?
What is the primary function of Eosinophil Chemotactic Factor (ECF)?
What is the primary function of Eosinophil Chemotactic Factor (ECF)?
What is the primary purpose of desensitization therapy?
What is the primary purpose of desensitization therapy?
What is the primary difference between an allergic reaction and an autoimmune disorder?
What is the primary difference between an allergic reaction and an autoimmune disorder?
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What is the purpose of the radioallergosorbent blood test (RAST)?
What is the purpose of the radioallergosorbent blood test (RAST)?
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What is the primary function of epinephrine in the treatment of anaphylaxis?
What is the primary function of epinephrine in the treatment of anaphylaxis?
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What is the primary purpose of elimination diets in the diagnosis of food allergies?
What is the primary purpose of elimination diets in the diagnosis of food allergies?
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What is the primary difference between a localized hypersensitivity reaction and an anaphylactic reaction?
What is the primary difference between a localized hypersensitivity reaction and an anaphylactic reaction?
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What is the primary purpose of scratch or prick testing in the diagnosis of allergies?
What is the primary purpose of scratch or prick testing in the diagnosis of allergies?
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What is the primary purpose of antinuclear antibody titer in the diagnosis of autoimmune disorders?
What is the primary purpose of antinuclear antibody titer in the diagnosis of autoimmune disorders?
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What characterizes an allergic disorder?
What characterizes an allergic disorder?
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What type of hypersensitivity response is mediated by immunoglobulin E (IgE) antibodies?
What type of hypersensitivity response is mediated by immunoglobulin E (IgE) antibodies?
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What is the process by which cellular and chemical events occur after a second or subsequent exposure to an allergen?
What is the process by which cellular and chemical events occur after a second or subsequent exposure to an allergen?
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What type of hypersensitivity response reaches a peak within 6 hours after exposure to an allergen?
What type of hypersensitivity response reaches a peak within 6 hours after exposure to an allergen?
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What is the result of a massive release of histamine in an anaphylactic response?
What is the result of a massive release of histamine in an anaphylactic response?
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What is the term for the acute swelling of the face, neck, lips, larynx, hands, feet, genitals, and internal organs in an anaphylactic response?
What is the term for the acute swelling of the face, neck, lips, larynx, hands, feet, genitals, and internal organs in an anaphylactic response?
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What type of hypersensitivity response involves the phagocytosis of antigens by macrophages and the production of cytokines by sensitized T cells?
What type of hypersensitivity response involves the phagocytosis of antigens by macrophages and the production of cytokines by sensitized T cells?
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What is the term for the rapid and profound type I hypersensitivity response?
What is the term for the rapid and profound type I hypersensitivity response?
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What is the result of the immediate hypersensitivity response in terms of blood pressure?
What is the result of the immediate hypersensitivity response in terms of blood pressure?
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What is the term for the inflammatory reaction that occurs in a delayed hypersensitivity response?
What is the term for the inflammatory reaction that occurs in a delayed hypersensitivity response?
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What is the primary mechanism of muscle weakness in Myasthenia Gravis?
What is the primary mechanism of muscle weakness in Myasthenia Gravis?
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Which of the following is NOT a symptom of Myasthenia Gravis?
Which of the following is NOT a symptom of Myasthenia Gravis?
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What is the purpose of the Tensilon test in diagnosing Myasthenia Gravis?
What is the purpose of the Tensilon test in diagnosing Myasthenia Gravis?
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What is the primary goal of nursing interventions in Myasthenia Gravis?
What is the primary goal of nursing interventions in Myasthenia Gravis?
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What is the criteria for diagnosing Systemic Lupus Erythematosus (SLE)?
What is the criteria for diagnosing Systemic Lupus Erythematosus (SLE)?
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What is the purpose of the Antinuclear Antibody test in SLE?
What is the purpose of the Antinuclear Antibody test in SLE?
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What is the primary goal of treatment in SLE?
What is the primary goal of treatment in SLE?
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What is the nursing intervention to reduce the risk of venous thromboembolism in SLE?
What is the nursing intervention to reduce the risk of venous thromboembolism in SLE?
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What is the importance of teaching clients with SLE to wear a medic-alert bracelet?
What is the importance of teaching clients with SLE to wear a medic-alert bracelet?
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What is the purpose of the C-reactive protein test in SLE?
What is the purpose of the C-reactive protein test in SLE?
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Which of the following is a characteristic of an autoimmune disorder?
Which of the following is a characteristic of an autoimmune disorder?
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What is the primary purpose of the scratch or prick test in the diagnosis of allergies?
What is the primary purpose of the scratch or prick test in the diagnosis of allergies?
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What is the term for the acute swelling of the face, neck, lips, larynx, hands, feet, genitals, and internal organs in an anaphylactic response?
What is the term for the acute swelling of the face, neck, lips, larynx, hands, feet, genitals, and internal organs in an anaphylactic response?
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What is the primary mechanism of desensitization therapy?
What is the primary mechanism of desensitization therapy?
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What is the primary goal of nursing interventions in Myasthenia Gravis?
What is the primary goal of nursing interventions in Myasthenia Gravis?
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What is the primary mechanism of corticosteroids in the treatment of allergic reactions?
What is the primary mechanism of corticosteroids in the treatment of allergic reactions?
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What is the term for the rapid and profound type I hypersensitivity response?
What is the term for the rapid and profound type I hypersensitivity response?
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What is the primary purpose of elimination diets in the diagnosis of food allergies?
What is the primary purpose of elimination diets in the diagnosis of food allergies?
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What is the primary mechanism of immunosuppressive agents in the treatment of autoimmune disorders?
What is the primary mechanism of immunosuppressive agents in the treatment of autoimmune disorders?
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What is the term for the process by which cellular and chemical events occur after a second or subsequent exposure to an allergen?
What is the term for the process by which cellular and chemical events occur after a second or subsequent exposure to an allergen?
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What is the primary characteristic of an allergic disorder?
What is the primary characteristic of an allergic disorder?
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What is the process by which the body responds to an initial exposure to an allergen?
What is the process by which the body responds to an initial exposure to an allergen?
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What type of hypersensitivity response is mediated by immunoglobulin M or G antibodies?
What type of hypersensitivity response is mediated by immunoglobulin M or G antibodies?
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What is the term for the acute swelling of the face, neck, lips, larynx, hands, feet, genitals, and internal organs in an anaphylactic response?
What is the term for the acute swelling of the face, neck, lips, larynx, hands, feet, genitals, and internal organs in an anaphylactic response?
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What is the primary mechanism of muscle weakness in Myasthenia Gravis?
What is the primary mechanism of muscle weakness in Myasthenia Gravis?
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What is the primary mechanism of the immediate hypersensitivity response?
What is the primary mechanism of the immediate hypersensitivity response?
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What is the purpose of the Tensilon test in diagnosing Myasthenia Gravis?
What is the purpose of the Tensilon test in diagnosing Myasthenia Gravis?
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What type of hypersensitivity response involves the production of cytokines by sensitized T cells?
What type of hypersensitivity response involves the production of cytokines by sensitized T cells?
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What is the primary goal of nursing interventions in Myasthenia Gravis?
What is the primary goal of nursing interventions in Myasthenia Gravis?
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What is the result of a massive release of histamine in an anaphylactic response?
What is the result of a massive release of histamine in an anaphylactic response?
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What is the criteria for diagnosing Systemic Lupus Erythematosus (SLE)?
What is the criteria for diagnosing Systemic Lupus Erythematosus (SLE)?
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What is the purpose of the Antinuclear Antibody test in SLE?
What is the purpose of the Antinuclear Antibody test in SLE?
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What is the term for the rapid and profound type I hypersensitivity response?
What is the term for the rapid and profound type I hypersensitivity response?
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What is the primary difference between immediate and delayed hypersensitivity responses?
What is the primary difference between immediate and delayed hypersensitivity responses?
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What is the primary goal of treatment in SLE?
What is the primary goal of treatment in SLE?
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What is the result of the immediate hypersensitivity response in terms of blood pressure?
What is the result of the immediate hypersensitivity response in terms of blood pressure?
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What is the nursing intervention to reduce the risk of venous thromboembolism in SLE?
What is the nursing intervention to reduce the risk of venous thromboembolism in SLE?
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What is the importance of teaching clients with SLE to wear a medic-alert bracelet?
What is the importance of teaching clients with SLE to wear a medic-alert bracelet?
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What is the purpose of the C-reactive protein test in SLE?
What is the purpose of the C-reactive protein test in SLE?
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What is the primary difference between Myasthenia Gravis and Systemic Lupus Erythematosus?
What is the primary difference between Myasthenia Gravis and Systemic Lupus Erythematosus?
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What type of hypersensitivity response is characterized by the phagocytosis of antigens by macrophages and the production of cytokines by sensitized T cells?
What type of hypersensitivity response is characterized by the phagocytosis of antigens by macrophages and the production of cytokines by sensitized T cells?
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What is the process by which an allergic response is triggered, resulting in sensitization to an allergen?
What is the process by which an allergic response is triggered, resulting in sensitization to an allergen?
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What is the term for the rapid and profound type I hypersensitivity response that can cause life-threatening symptoms?
What is the term for the rapid and profound type I hypersensitivity response that can cause life-threatening symptoms?
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What type of hypersensitivity response is mediated by immunoglobulin E (IgE) antibodies?
What type of hypersensitivity response is mediated by immunoglobulin E (IgE) antibodies?
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What is the result of a massive release of histamine in an anaphylactic response?
What is the result of a massive release of histamine in an anaphylactic response?
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What is the primary characteristic of an allergic disorder?
What is the primary characteristic of an allergic disorder?
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What is the primary mechanism by which corticosteroids block the synthesis of prostaglandins and leukotrienes?
What is the primary mechanism by which corticosteroids block the synthesis of prostaglandins and leukotrienes?
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What is the primary difference between an allergic reaction and an autoimmune disorder?
What is the primary difference between an allergic reaction and an autoimmune disorder?
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What is the primary purpose of desensitization therapy in the treatment of allergic reactions?
What is the primary purpose of desensitization therapy in the treatment of allergic reactions?
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What is the primary mechanism of immunosuppressive agents in the treatment of autoimmune disorders?
What is the primary mechanism of immunosuppressive agents in the treatment of autoimmune disorders?
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What is the primary characteristic of an allergic disorder?
What is the primary characteristic of an allergic disorder?
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What is the primary purpose of the erythrocyte sedimentation rate (ESR) test in the diagnosis of autoimmune disorders?
What is the primary purpose of the erythrocyte sedimentation rate (ESR) test in the diagnosis of autoimmune disorders?
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Which of the following is a characteristic of Myasthenia Gravis?
Which of the following is a characteristic of Myasthenia Gravis?
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Which of the following is a diagnostic test for Systemic Lupus Erythematosus (SLE)?
Which of the following is a diagnostic test for Systemic Lupus Erythematosus (SLE)?
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What is the primary goal of nursing interventions in clients with Myasthenia Gravis?
What is the primary goal of nursing interventions in clients with Myasthenia Gravis?
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What is the primary mechanism of action of corticosteroids in the treatment of autoimmune disorders?
What is the primary mechanism of action of corticosteroids in the treatment of autoimmune disorders?
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Which of the following is a symptom of Myasthenia Gravis?
Which of the following is a symptom of Myasthenia Gravis?
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What is the primary goal of treatment in clients with Systemic Lupus Erythematosus (SLE)?
What is the primary goal of treatment in clients with Systemic Lupus Erythematosus (SLE)?
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Which of the following is a characteristic of autoimmune disorders?
Which of the following is a characteristic of autoimmune disorders?
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What is the primary purpose of the Antinuclear Antibody test in diagnosing Systemic Lupus Erythematosus (SLE)?
What is the primary purpose of the Antinuclear Antibody test in diagnosing Systemic Lupus Erythematosus (SLE)?
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Study Notes
Allergic Disorders
- Characterized by a hyperimmune response to weak antigens that are usually harmless
- Types of allergens: ingestants (food, drugs), inhalants (house dust and mites), contactants (latex), and injectants (drugs, bee venom)
- Examples of allergic disorders: allergic rhinitis, contact dermatitis, food allergy, urticaria, and angioedema
Pathophysiology and Etiology
- First exposure to an allergen does not produce symptoms
- Sensitization: process by which cellular and chemical events occur after a second or subsequent exposure to an allergen
- Four types of hypersensitivity responses: type I, II, III, and IV
Immediate Hypersensitivity Response
- Type I, atopic or anaphylactic: mediated by immunoglobulin E (IgE) antibodies
- Type II, cytotoxic: mediated by immunoglobulin M or G (IgM or IgG) antibodies
- Type III, immune complex: mediated by IgG antibodies
- Anaphylaxis: rapid and profound type I hypersensitivity response
Delayed Hypersensitivity Response
- Type IV: mediated by T cells and macrophages
- May develop over several hours or days
Suppression of the Allergic Response
- Mechanisms: Eosinophil Chemotactic Factor (ECF), epinephrine, and corticosteroids
- Assessment findings: manifestations of allergic reactions, such as shock, laryngeal edema, wheezing, and angioneurotic edema
Diagnostic Findings
- Radioallergosorbent blood test (RAST)
- Skin testing with extracts of various substances (antigens)
- Elimination diets
Complications
- Clients with inhalant allergies or allergic rhinitis may develop nasal polyps, sinus infections, secondary pulmonary infections, asthma, and epistaxis
- Medical management: drug therapy, desensitization, and sublingual-swallow immunotherapy
Nursing Management
- Remove rings from swollen fingers to maintain circulation
- Schedule for diagnostic skin testing and avoid taking prescribed or OTC antihistamines or cold preparations for at least 48 to 72 hours before testing
- Instruct on the use of Epipen and administer serial doses and monitor after desensitization
- Client and family teaching to avoiding or reducing exposure
Autoimmune Disorders
- Characterized by unrelenting, progressive tissue damage without any verifiable etiology
- Examples: hemolytic anemia, multiple sclerosis, myasthenia gravis, and ulcerative colitis
Pathophysiology and Etiology
- Causes: tissue injury theory, genetic instruction theory, and sequestered antigen theory
- Assessment findings: symptoms depend on the tissues and organs affected, characteristic of an acute inflammatory response
Diagnostic Findings
- Erythrocyte sedimentation rate (ESR), antistreptolysin O titer, antinuclear antibody titer, and rheumatoid factor
- Medical management: drug therapy, immunosuppressive agents, cytotoxic agents, and corticosteroids
Nursing Management
- Obtain a family history and vital signs
- Examine the client for signs of localized inflammation and compromised body functions
- Assess level of energy and review laboratory test findings
- Client and family teaching
Autoimmune Disorder - Myasthenia Gravis
- Chronic autoimmune disorder characterized by episodes of weakness in voluntary muscles
- Pathophysiology: thymus gland produces antibodies that block or reduce acetylcholine receptors at the neuromuscular junction
- Symptoms: weakness of facial, speech, and chewing muscles, droopy eye (ptosis), diplopia (double vision), dysphagia, and dyspnea
Diagnosis
- Elevated blood levels of acetylcholine receptor antibodies
- Injection of Tensilon (short-acting anticholinergic) improvement in muscle strength
- EMG will show increased muscle fatigue
- CT scan may show a tumor of the thymus
Treatment
- Anticholinesterase agents, corticosteroids, cytotoxic agents, and thymectomy
- Nursing intervention: prevent respiratory/swallowing problems and fatigue, maintain airway, teach signs and symptoms of myasthenia crisis, and teach client and family medications must be taken on time
Autoimmune Disorders - Systemic Lupus Erythematosus (SLE)
- Chronic inflammatory connective tissue disease that affects multiple body systems
- Pathophysiology: production of autoantibodies react with antigen to form immune complexes, affecting blood and lymphatic vessels
- Symptoms: butterfly face rash, discoid rash, sun-related rash, thrombocytopenia, leukopenia, mouth sores, polyarthritis, and neurological symptoms
Criteria for Diagnosis
- Need 4 or more of the following criteria: butterfly face rash, discoid rash, sun-related rash, thrombocytopenia, leukopenia, mouth sores, polyarthritis, and neurological symptoms
Diagnostic Tests
- Antinuclear antibody test, anti-DNA antibody test, C-reactive protein, ESR, CBC, and U/A and renal function studies
Treatment
- No cure, focus on preventing complications, minimizing disability, and preventing organ damage
- Immunosuppressive drug, steroids, and sun exposure avoidance
- Nursing interventions: maintain good nutrition, balance rest and activity, stress reduction, encourage exercise, and teach signs and symptoms of infection and medication management
Allergic Disorders
- Characterized by a hyperimmune response to weak antigens that are usually harmless
- Types of allergens: ingestants (food, drugs), inhalants (house dust and mites), contactants (latex), and injectants (drugs, bee venom)
- Examples of allergic disorders: allergic rhinitis, contact dermatitis, food allergy, urticaria, and angioedema
Pathophysiology and Etiology
- First exposure to an allergen does not produce symptoms
- Sensitization: process by which cellular and chemical events occur after a second or subsequent exposure to an allergen
- Four types of hypersensitivity responses: type I, II, III, and IV
Immediate Hypersensitivity Response
- Type I, atopic or anaphylactic: mediated by immunoglobulin E (IgE) antibodies
- Type II, cytotoxic: mediated by immunoglobulin M or G (IgM or IgG) antibodies
- Type III, immune complex: mediated by IgG antibodies
- Anaphylaxis: rapid and profound type I hypersensitivity response
Delayed Hypersensitivity Response
- Type IV: mediated by T cells and macrophages
- May develop over several hours or days
Suppression of the Allergic Response
- Mechanisms: Eosinophil Chemotactic Factor (ECF), epinephrine, and corticosteroids
- Assessment findings: manifestations of allergic reactions, such as shock, laryngeal edema, wheezing, and angioneurotic edema
Diagnostic Findings
- Radioallergosorbent blood test (RAST)
- Skin testing with extracts of various substances (antigens)
- Elimination diets
Complications
- Clients with inhalant allergies or allergic rhinitis may develop nasal polyps, sinus infections, secondary pulmonary infections, asthma, and epistaxis
- Medical management: drug therapy, desensitization, and sublingual-swallow immunotherapy
Nursing Management
- Remove rings from swollen fingers to maintain circulation
- Schedule for diagnostic skin testing and avoid taking prescribed or OTC antihistamines or cold preparations for at least 48 to 72 hours before testing
- Instruct on the use of Epipen and administer serial doses and monitor after desensitization
- Client and family teaching to avoiding or reducing exposure
Autoimmune Disorders
- Characterized by unrelenting, progressive tissue damage without any verifiable etiology
- Examples: hemolytic anemia, multiple sclerosis, myasthenia gravis, and ulcerative colitis
Pathophysiology and Etiology
- Causes: tissue injury theory, genetic instruction theory, and sequestered antigen theory
- Assessment findings: symptoms depend on the tissues and organs affected, characteristic of an acute inflammatory response
Diagnostic Findings
- Erythrocyte sedimentation rate (ESR), antistreptolysin O titer, antinuclear antibody titer, and rheumatoid factor
- Medical management: drug therapy, immunosuppressive agents, cytotoxic agents, and corticosteroids
Nursing Management
- Obtain a family history and vital signs
- Examine the client for signs of localized inflammation and compromised body functions
- Assess level of energy and review laboratory test findings
- Client and family teaching
Autoimmune Disorder - Myasthenia Gravis
- Chronic autoimmune disorder characterized by episodes of weakness in voluntary muscles
- Pathophysiology: thymus gland produces antibodies that block or reduce acetylcholine receptors at the neuromuscular junction
- Symptoms: weakness of facial, speech, and chewing muscles, droopy eye (ptosis), diplopia (double vision), dysphagia, and dyspnea
Diagnosis
- Elevated blood levels of acetylcholine receptor antibodies
- Injection of Tensilon (short-acting anticholinergic) improvement in muscle strength
- EMG will show increased muscle fatigue
- CT scan may show a tumor of the thymus
Treatment
- Anticholinesterase agents, corticosteroids, cytotoxic agents, and thymectomy
- Nursing intervention: prevent respiratory/swallowing problems and fatigue, maintain airway, teach signs and symptoms of myasthenia crisis, and teach client and family medications must be taken on time
Autoimmune Disorders - Systemic Lupus Erythematosus (SLE)
- Chronic inflammatory connective tissue disease that affects multiple body systems
- Pathophysiology: production of autoantibodies react with antigen to form immune complexes, affecting blood and lymphatic vessels
- Symptoms: butterfly face rash, discoid rash, sun-related rash, thrombocytopenia, leukopenia, mouth sores, polyarthritis, and neurological symptoms
Criteria for Diagnosis
- Need 4 or more of the following criteria: butterfly face rash, discoid rash, sun-related rash, thrombocytopenia, leukopenia, mouth sores, polyarthritis, and neurological symptoms
Diagnostic Tests
- Antinuclear antibody test, anti-DNA antibody test, C-reactive protein, ESR, CBC, and U/A and renal function studies
Treatment
- No cure, focus on preventing complications, minimizing disability, and preventing organ damage
- Immunosuppressive drug, steroids, and sun exposure avoidance
- Nursing interventions: maintain good nutrition, balance rest and activity, stress reduction, encourage exercise, and teach signs and symptoms of infection and medication management
Allergic Disorders
- Characterized by a hyperimmune response to weak antigens that are usually harmless
- Types of allergens: ingestants (food, drugs), inhalants (house dust and mites), contactants (latex), and injectants (drugs, bee venom)
- Examples of allergic disorders: allergic rhinitis, contact dermatitis, food allergy, urticaria, and angioedema
Pathophysiology and Etiology
- First exposure to an allergen does not produce symptoms
- Sensitization: process by which cellular and chemical events occur after a second or subsequent exposure to an allergen
- Four types of hypersensitivity responses: type I, II, III, and IV
Immediate Hypersensitivity Response
- Type I, atopic or anaphylactic: mediated by immunoglobulin E (IgE) antibodies
- Type II, cytotoxic: mediated by immunoglobulin M or G (IgM or IgG) antibodies
- Type III, immune complex: mediated by IgG antibodies
- Anaphylaxis: rapid and profound type I hypersensitivity response
Delayed Hypersensitivity Response
- Type IV: mediated by T cells and macrophages
- May develop over several hours or days
Suppression of the Allergic Response
- Mechanisms: Eosinophil Chemotactic Factor (ECF), epinephrine, and corticosteroids
- Assessment findings: manifestations of allergic reactions, such as shock, laryngeal edema, wheezing, and angioneurotic edema
Diagnostic Findings
- Radioallergosorbent blood test (RAST)
- Skin testing with extracts of various substances (antigens)
- Elimination diets
Complications
- Clients with inhalant allergies or allergic rhinitis may develop nasal polyps, sinus infections, secondary pulmonary infections, asthma, and epistaxis
- Medical management: drug therapy, desensitization, and sublingual-swallow immunotherapy
Nursing Management
- Remove rings from swollen fingers to maintain circulation
- Schedule for diagnostic skin testing and avoid taking prescribed or OTC antihistamines or cold preparations for at least 48 to 72 hours before testing
- Instruct on the use of Epipen and administer serial doses and monitor after desensitization
- Client and family teaching to avoiding or reducing exposure
Autoimmune Disorders
- Characterized by unrelenting, progressive tissue damage without any verifiable etiology
- Examples: hemolytic anemia, multiple sclerosis, myasthenia gravis, and ulcerative colitis
Pathophysiology and Etiology
- Causes: tissue injury theory, genetic instruction theory, and sequestered antigen theory
- Assessment findings: symptoms depend on the tissues and organs affected, characteristic of an acute inflammatory response
Diagnostic Findings
- Erythrocyte sedimentation rate (ESR), antistreptolysin O titer, antinuclear antibody titer, and rheumatoid factor
- Medical management: drug therapy, immunosuppressive agents, cytotoxic agents, and corticosteroids
Nursing Management
- Obtain a family history and vital signs
- Examine the client for signs of localized inflammation and compromised body functions
- Assess level of energy and review laboratory test findings
- Client and family teaching
Autoimmune Disorder - Myasthenia Gravis
- Chronic autoimmune disorder characterized by episodes of weakness in voluntary muscles
- Pathophysiology: thymus gland produces antibodies that block or reduce acetylcholine receptors at the neuromuscular junction
- Symptoms: weakness of facial, speech, and chewing muscles, droopy eye (ptosis), diplopia (double vision), dysphagia, and dyspnea
Diagnosis
- Elevated blood levels of acetylcholine receptor antibodies
- Injection of Tensilon (short-acting anticholinergic) improvement in muscle strength
- EMG will show increased muscle fatigue
- CT scan may show a tumor of the thymus
Treatment
- Anticholinesterase agents, corticosteroids, cytotoxic agents, and thymectomy
- Nursing intervention: prevent respiratory/swallowing problems and fatigue, maintain airway, teach signs and symptoms of myasthenia crisis, and teach client and family medications must be taken on time
Autoimmune Disorders - Systemic Lupus Erythematosus (SLE)
- Chronic inflammatory connective tissue disease that affects multiple body systems
- Pathophysiology: production of autoantibodies react with antigen to form immune complexes, affecting blood and lymphatic vessels
- Symptoms: butterfly face rash, discoid rash, sun-related rash, thrombocytopenia, leukopenia, mouth sores, polyarthritis, and neurological symptoms
Criteria for Diagnosis
- Need 4 or more of the following criteria: butterfly face rash, discoid rash, sun-related rash, thrombocytopenia, leukopenia, mouth sores, polyarthritis, and neurological symptoms
Diagnostic Tests
- Antinuclear antibody test, anti-DNA antibody test, C-reactive protein, ESR, CBC, and U/A and renal function studies
Treatment
- No cure, focus on preventing complications, minimizing disability, and preventing organ damage
- Immunosuppressive drug, steroids, and sun exposure avoidance
- Nursing interventions: maintain good nutrition, balance rest and activity, stress reduction, encourage exercise, and teach signs and symptoms of infection and medication management
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Description
Learn about the characteristics of allergic disorders, including the types of allergens and examples of allergic reactions. Understand how allergens enter the body and trigger intense responses.