Allergic Contact Dermatitis Immunology Quiz
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Questions and Answers

What is the main immune mechanism involved in Cell-Mediated (Delayed) Hypersensitivity?

  • Antibody production
  • Interaction between sensitized T lymphocytes & specific antigens (correct)
  • Complement activation
  • B lymphocyte proliferation

Which type of T lymphocytes are involved in activating macrophages during Cell-Mediated (Delayed) Hypersensitivity?

  • CD4+ Th2 cells
  • CD4+ Treg cells
  • CD4+ Th1 cells (correct)
  • CD8+ CTLs

Which of the following microbes is NOT a major immune response target in delayed type hypersensitivity reactions?

  • Measles virus
  • Mycobacterium T.B.
  • Streptococcus pyogenes (correct)
  • Leishmania species

What is the time frame for the development of Cell-Mediated (Delayed) Hypersensitivity reactions?

<p>Within 1-2 days (A)</p> Signup and view all the answers

Which component plays NO role in Cell-Mediated (Delayed) Hypersensitivity reactions?

<p>Antibodies (A)</p> Signup and view all the answers

What is the main function of CD8+ CTLs in Cell-Mediated (Delayed) Hypersensitivity?

<p>Directly kill infected cells (C)</p> Signup and view all the answers

What type of cells are involved in the immunological features of Allergic contact dermatitis?

<p>Langerhans cells (D)</p> Signup and view all the answers

Which type of hypersensitivity reaction is indicative of Allergic contact dermatitis?

<p>Type 4 HS (C)</p> Signup and view all the answers

How is the diagnosis of Allergic contact dermatitis confirmed?

<p>History and patch test (A)</p> Signup and view all the answers

What is the characteristic feature of the acute form of allergic contact dermatitis?

<p>Erythema, oedema, vesiculation (D)</p> Signup and view all the answers

Which parts of the body can provide a clue for diagnosing Allergic contact dermatitis based on the site of the lesion?

<p>Ear lobes, around neck, wrist (D)</p> Signup and view all the answers

What is the main purpose of a patch test in diagnosing Allergic contact dermatitis?

<p>To place a low dose of suspected Ag(s) on the skin (B)</p> Signup and view all the answers

What is the main cause of allergic contact dermatitis?

<p>Contact with sensitizing substances or antigens (A)</p> Signup and view all the answers

Which of the following is NOT a common substance that can cause allergic contact dermatitis?

<p>Vaccines (B)</p> Signup and view all the answers

In allergic contact dermatitis, haptens can complex with skin proteins leading to:

<p>Skin irritation (B)</p> Signup and view all the answers

Which of the following groups of people are more likely to experience anergy in the context of allergic contact dermatitis?

<p>Individuals with immunosuppressive illnesses (C)</p> Signup and view all the answers

Which of the following is NOT a common plant that can cause allergic contact dermatitis?

<p>Hemlock (D)</p> Signup and view all the answers

What type of molecules are many substances that cause allergic contact dermatitis?

<p>Haptens that complex with skin proteins (D)</p> Signup and view all the answers

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