Allergic Contact Dermatitis Immunology Quiz

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What is the main immune mechanism involved in Cell-Mediated (Delayed) Hypersensitivity?

Antibody production

Interaction between sensitized T lymphocytes & specific antigens (correct)

Complement activation

B lymphocyte proliferation

Which type of T lymphocytes are involved in activating macrophages during Cell-Mediated (Delayed) Hypersensitivity?

CD4+ Th2 cells

CD4+ Treg cells

CD4+ Th1 cells (correct)

CD8+ CTLs

Which of the following microbes is NOT a major immune response target in delayed type hypersensitivity reactions?

Measles virus

Mycobacterium T.B.

Streptococcus pyogenes (correct)

Leishmania species

What is the time frame for the development of Cell-Mediated (Delayed) Hypersensitivity reactions?

Within 1-2 days Signup and view all the answers

Which component plays NO role in Cell-Mediated (Delayed) Hypersensitivity reactions?

Antibodies Signup and view all the answers

What is the main function of CD8+ CTLs in Cell-Mediated (Delayed) Hypersensitivity?

Directly kill infected cells Signup and view all the answers

What type of cells are involved in the immunological features of Allergic contact dermatitis?

Langerhans cells Signup and view all the answers

Which type of hypersensitivity reaction is indicative of Allergic contact dermatitis?

Type 4 HS Signup and view all the answers

How is the diagnosis of Allergic contact dermatitis confirmed?

History and patch test Signup and view all the answers

What is the characteristic feature of the acute form of allergic contact dermatitis?

Erythema, oedema, vesiculation Signup and view all the answers

Which parts of the body can provide a clue for diagnosing Allergic contact dermatitis based on the site of the lesion?

Ear lobes, around neck, wrist Signup and view all the answers

What is the main purpose of a patch test in diagnosing Allergic contact dermatitis?

To place a low dose of suspected Ag(s) on the skin Signup and view all the answers

What is the main cause of allergic contact dermatitis?

Contact with sensitizing substances or antigens Signup and view all the answers

Which of the following is NOT a common substance that can cause allergic contact dermatitis?

Vaccines Signup and view all the answers

In allergic contact dermatitis, haptens can complex with skin proteins leading to:

Skin irritation Signup and view all the answers

Which of the following groups of people are more likely to experience anergy in the context of allergic contact dermatitis?

Individuals with immunosuppressive illnesses Signup and view all the answers

Which of the following is NOT a common plant that can cause allergic contact dermatitis?

Hemlock Signup and view all the answers

What type of molecules are many substances that cause allergic contact dermatitis?

Haptens that complex with skin proteins Signup and view all the answers