Podcast
Questions and Answers
What is the generic name of the drug?
What is the generic name of the drug?
- Albuterol (correct)
- Salbutamol
- Proventil
- ProAir HFA
Which of the following is NOT a trade name for Albuterol?
Which of the following is NOT a trade name for Albuterol?
- ProAir HFA
- Proventil
- Salbutamol
- Ibuprofen (correct)
What classification does Albuterol fall under?
What classification does Albuterol fall under?
Adrenergic B2-Adrenergic, sympathomimetic, bronchodilator
What is the recommended dose for Albuterol?
What is the recommended dose for Albuterol?
How often can Albuterol be administered?
How often can Albuterol be administered?
What are the common routes for administering Albuterol?
What are the common routes for administering Albuterol?
What is the peak effect time for Albuterol when taken via inhalation?
What is the peak effect time for Albuterol when taken via inhalation?
What is the onset time for Albuterol via inhalation?
What is the onset time for Albuterol via inhalation?
What is the normal dose range for Albuterol?
What is the normal dose range for Albuterol?
What lab alterations may be caused by Albuterol?
What lab alterations may be caused by Albuterol?
List one indicated use for Albuterol.
List one indicated use for Albuterol.
What is the action of Albuterol?
What is the action of Albuterol?
What must be assessed before administering Albuterol?
What must be assessed before administering Albuterol?
What is a major side effect of Albuterol?
What is a major side effect of Albuterol?
What needs to be done post-administration of Albuterol?
What needs to be done post-administration of Albuterol?
What are the nursing considerations for Albuterol?
What are the nursing considerations for Albuterol?
What interactions should be noted with Albuterol?
What interactions should be noted with Albuterol?
What is a contraindication for using Albuterol?
What is a contraindication for using Albuterol?
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Study Notes
Albuterol Overview
- Generic name: Albuterol
- Trade names: ProAir HFA, ProAir RespiClick, Proventil, Proventil HFA, ReliOn, Salbutamol
Classification and Mechanism
- Classification: Adrenergic B2-Adrenergic, sympathomimetic, bronchodilator
- Mechanism of action: Causes bronchodilation by stimulating B2 receptors, increasing cAMP levels that relax smooth muscle; effects include CNS and cardiac stimulation, enhanced diuresis, and gastric acid secretion.
Dosage and Administration
- Standard dose: 2 puffs (180 mcg) via inhalation
- Routes of administration: Inhalation (INH), orally (po), nebulization (Neb/IPPB)
- Timing: Typically taken q4-6 hours as needed
- Normal dosage range: 180 mcg to 32 mg
Pharmacokinetics
- Onset of action:
- PO: 30 minutes
- INH: 5-15 minutes
- Peak effect:
- PO: 2-3 hours
- INH: 1.5-2 hours
- Duration of action:
- PO: 4-6 hours
- INH: 2-6 hours
Therapeutic Uses
- Indicated for prevention of:
- Exercise-induced asthma
- Acute bronchospasm
- Bronchitis, emphysema, bronchiectasis
- Unlabeled uses include:
- Hyperkalemia in dialysis patients
- Chronic Obstructive Pulmonary Disease (COPD)
Laboratory Considerations
- Notable lab alteration: Decreases potassium levels
Nursing Implications
-
Pre-administration assessment criteria:
- Evaluate respiratory function (vital capacity, ABGs)
- Monitor lung sounds, heart rate, blood pressure
- Assess patient's self-medication capability
- Confirm absence of allergic reactions or signs of paradoxical bronchospasm
-
Hold administration if:
- Paradoxical bronchospasm or hypokalemia is evident
-
Post-administration expectations:
- Absence of dyspnea or wheezing
- Improved airway exchange and ABGs
Side Effects and Adverse Reactions
- CNS: Tremors, anxiety, insomnia, headache, hallucinations
- Cardiovascular: Palpitations, tachycardia, angina, dysrhythmias
- EENT: Dry nose, throat irritation
- GI: Heartburn, nausea, vomiting
- Miscellaneous: Flushing, sweating, hypokalemia, muscle cramps, paradoxical bronchospasm
Patient Education
- Emphasize adherence to prescribed use and management of missed doses
- Demonstrate inhaler technique, including shaking and priming
- Warn against using near heat or flames and avoid eye contact with aerosol
- Instruct to wash inhaler regularly and discard after labeled uses are depleted
- Advise limiting caffeine intake to reduce stimulation risk
Drug Interactions
- Increased effects with:
- CNS stimulants, potassium-losing diuretics, digoxin, other adrenergics, tricyclics, MAOIs
- Decreased effects when used with:
- Beta-blockers
- Possible severe hypotension when combined with oxytocics
Contraindications and Precautions
- Contraindications: Hypersensitivity to sympathomimetics
- Precautions for use in patients with:
- Pregnancy, cardiac/renal issues, hyperthyroidism, diabetes, hypertension
- Age-related considerations for pediatric asthma management
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