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Questions and Answers
What does the 'S' in HIrisPlex-S stand for?
What does the 'S' in HIrisPlex-S stand for?
How many SNPs does the HIrisPlex-S system target for skin color prediction?
How many SNPs does the HIrisPlex-S system target for skin color prediction?
Which model is used for eye color prediction in the HIrisPlex-S system?
Which model is used for eye color prediction in the HIrisPlex-S system?
What was the minimum amount of DNA required to obtain complete SNP profiles using the 17-plex assay?
What was the minimum amount of DNA required to obtain complete SNP profiles using the 17-plex assay?
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What is a key feature of the HIrisPlex website?
What is a key feature of the HIrisPlex website?
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What challenge does agricultural biotechnology aim to address?
What challenge does agricultural biotechnology aim to address?
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Which of the following is NOT a key strategy for the responsible use of agricultural biotechnology?
Which of the following is NOT a key strategy for the responsible use of agricultural biotechnology?
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What is metabolomics primarily focused on studying?
What is metabolomics primarily focused on studying?
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How does Forensic DNA Phenotyping (FDP) assist in investigations?
How does Forensic DNA Phenotyping (FDP) assist in investigations?
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Which of the following areas is NOT mentioned as a focus of current metabolomics research?
Which of the following areas is NOT mentioned as a focus of current metabolomics research?
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What is a significant benefit of advancements in NMR and MS technologies?
What is a significant benefit of advancements in NMR and MS technologies?
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Which statement about ethical concerns in agricultural biotechnology is true?
Which statement about ethical concerns in agricultural biotechnology is true?
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What distinct application does the IrisPlex DNA test system have?
What distinct application does the IrisPlex DNA test system have?
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Study Notes
Agricultural Biotechnology
- Global demands for food, bioenergy, and specialty products, coupled with environmental changes, present substantial challenges to agricultural production.
- Agricultural biotechnology offers a promising solution, but ethical and sociocultural concerns must be addressed for widespread trust and adoption.
- Effective solutions need to be ethical, socially responsive, relevant to diverse backgrounds, and communicated clearly to the public.
- Ethical approaches, principled decision-making, citizen-stakeholder participation, science communication, and bioethics education are important to guide responsible agricultural biotechnology use.
Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) in Livestock Metabolomics
- Advances in NMR, MS, and omics sciences have improved understanding of molecular mechanisms and pathways related to animal physiology and pathology.
- Metabolomics is a post-genomics tool analyzing small molecular metabolites to provide insight into organism status over time.
- Researchers are focusing on metabolomics studies in livestock due to its value in livestock management and precision dairying.
- The goal of current research is to provide insights into the current research output from various areas of livestock, including nutri-metabolomics, disease diagnosis, reproductive disorders, pharmaco-metabolomics, genomics studies, and dairy production.
Forensic DNA Phenotyping (FDP)
- FDP predicts visible human traits from DNA, aiding in investigations.
- It has become an important advancement because it provides intelligence information from DNA traces helping police investigations.
- Standard DNA profiling often has limited use for identifying unknown perpetrators.
- The IrisPlex DNA test system, in this context, can predict eye color from trace DNA.
- A new system, IrisPlex-S, provides simultaneous prediction of eye, hair, and skin color from trace DNA.
- This system utilizes SNPs (single nucleotide polymorphisms) to perform these predictions.
- A 17-plex assay, developed in accordance with SWGDAM guidelines, achieves the accuracy of 24-plex assay even with very low quantity of sample.
- The IrisPlex-S methodology allows estimating probabilities for individual skin, eye, and hair color categories.
- The IrisPlex-S DNA test represents the first validated tool for simultaneous prediction of eye, hair, and skin color from DNA.
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Description
This quiz explores the challenges and solutions in agricultural biotechnology, especially in addressing global food demands and environmental changes. It also emphasizes the importance of ethical considerations, public communication, and stakeholder participation for the responsible use of biotechnology in agriculture.