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Questions and Answers
What is the duration of the term for Semester AY 2024-2025?
What is the duration of the term for Semester AY 2024-2025?
What percentage of the total grade does attendance and class participation account for in the lecture components?
What percentage of the total grade does attendance and class participation account for in the lecture components?
Which unit focuses on the chemical basis of heredity?
Which unit focuses on the chemical basis of heredity?
Which of the following activities is scheduled during the BU Olympics week?
Which of the following activities is scheduled during the BU Olympics week?
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What is the meaning of the Greek word 'gen' from which 'genetics' is derived?
What is the meaning of the Greek word 'gen' from which 'genetics' is derived?
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Who coined the term genetics?
Who coined the term genetics?
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Which theory proposed that body modifications could be transmitted to offspring?
Which theory proposed that body modifications could be transmitted to offspring?
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What did Weismann’s Germplasm Theory challenge?
What did Weismann’s Germplasm Theory challenge?
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What did Gregor Mendel discover about hereditary characteristics?
What did Gregor Mendel discover about hereditary characteristics?
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According to the Theory of Pangenesis, what did semen represent?
According to the Theory of Pangenesis, what did semen represent?
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Study Notes
Important Dates
- First Semester of AY 2024-2025 begins August 12, 2024 and ends December 15, 2024
- Last day to drop subjects is September 25, 2024
- Midterm exam scheduled for October 8-12, 2024 for both graduating and non-graduating students
- Midterm Interlude is October 28 to November 03, 2024
- Final exam is December 10-14, 2024
Agri 13: Principles of Genetics
- Course Instructor: Mr. Roy R. Boten, Lic.Agr.
- Laboratory Instructor: Prof. Andrian Sola
- Credit Units: 3.0
- Lecture: 2 units, Monday, 1-3 PM
- Laboratory: 1 unit, Wednesday, 7-10 AM
Course Grading
- Lecture Components (50%)
- Attendance and Class Participation (10%)
- Short and Long Quizzes (15%)
- Lecture Activities/Guide Questions (30%)
- Two Examinations (45%)
Topics for the Semester
- Unit I – Introduction to Genetics
- Unit II – Chromosomal Basis of Heredity
- Unit III – Gene Segregation and Interaction
- Unit IV – Linkage and Recombination
- Unit V – The DNA: Chemical Basis of Heredity
- Unit VI – Gene Functions
- Unit VII – Developmental Genetics
- Unit VIII – Epigenetics and Mutations
- Unit IX – Delayed Chromosomal and Extrachromosomal Inheritance
- Unit X – Quantitative and Population Genetics
- Unit XI – Human Genetics
Weekly Lecture Schedule
- Week 1 (August 12-16): Course Orientation and Introduction
- Week 2 (August 19-23): Unit I – Introduction to Genetics
- Week 3 (August 27-30): Unit II – Chromosomal Basis of Heredity
- Week 4 (September 2-6): Unit II – Chromosomal Basis of Heredity
- Week 5 (September 9-13): Unit III – Gene Segregation and Interaction
- Week 6 (September 16-20): Unit III – Gene Segregation and Interaction
- Week 7 (September 23-27): Unit IV – Linkage and Recombination
- Week 8 (September 30 to October 04): Unit V – The DNA: Chemical Basis of Heredity
- Week 9 (October 7-11): Midterm Examination
- Week 10 (October 14-18): Unit VI – Gene Functions
- Week 11 (October 21-25): BU Olympics (Developmental Genetics)
- Week 12 (October 28-31): Midterm Interlude
- Week 13 (November 4-8): Unit VII – Developmental Genetics and Unit VIII – Epigenetics and Mutations
- Week 14 (November 11-15): Unit IX – Delayed Chromosomal and Extrachromosomal Inheritance
- Week 15 (November 18-22): Unit X - Quantitative and Population Genetics
- Week 16 (November 25-29): Unit XI – Human Genetics
- Week 17 (December 2-6): Integration Period/Review Week
- Week 18 (December 9-13): Final Examination
Genetics: The Science of Heredity and Variation
- Genetics derived from the Greek word "gen", meaning to "become" or "grow into" something.
- The term "Genetics" coined by William Bateson in 1906.
- Gregor Mendel (1822-1884) considered "Father of Genetics", for his discoveries about hereditary characteristics and how they pass between generations.
Key Attributes of a Gene
- Passed down from generation to generation.
- Provides information about the structure, function, and biological properties of the traits it controls.
Early Theories of Inheritance
- Theory of Pangenesis: Aristotle proposed that semen was formed in every part of the body and reflected the characteristics of that part.
- Theory of Inheritance of Acquired Characteristics: Proposed by Jean-Baptiste Lamarck, suggested modifications acquired through use or disuse could be transmitted to offspring.
- Weismann’s Germplasm Theory: Weismann challenged the Theory of Pangenesis through experiments on mice. His work suggested that traits were not inherited through particles from the body, but through the sex cells (germplasm).
Key Differences Between Lamarck and Weismann's Theories
- Use and Disuse: Lamarck's theory focused on traits developing or diminishing during an organism's lifetime due to usage or lack thereof.
- Acquired Characteristics: Lamarck's theory proposed that these developed traits could then be inherited by the next generation.
Important Figures in the History of Genetics
- Joseph Gottlieb Kolreuter (1733-1806): Observed the diversity in offspring of hybrid plants although they initially appeared uniform.
- Carl Correns (Germany), Erick Von Tschermak (Austria), and Hugo de Vries (Netherlands) (1900): Independently duplicated Mendel's experiments and rediscovered his principles of inheritance.
- William Bateson, Saunders, and Cuenot (1902): Demonstrated the applicability of Mendel's principles to animals.
- Walter S. Sutton (USA) and Theodor Boveri (Germany) (1903): Suggested the association of Mendelian factors with chromosomes.
- Thomas Hunt Morgan (1910) and Calvin B. Bridges (1916): Demonstrated that each chromosome contained multiple genes.
The Chromosome Theory of Inheritance
- This theory was groundbreaking in linking genes directly to chromosomes.
- It helped explain how specific genes are passed down in inheritance.
Key Developments in Understanding DNA
- Oswald T. Avery, Collin M. Macleod, and Maclyn McCarty (1940): Identified DNA as the hereditary material.
- Rosalind Franklin: Used x-ray crystallography to obtain images of DNA, which were crucial in helping James Watson and Francis Crick create their DNA model.
Watson and Crick's DNA Model
- James Watson and Francis Crick, using Rosalind Franklin’s data, created the famous two-strand, or double-helix, model of DNA in 1953.
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Description
Test your understanding of key concepts in Agri 13: Principles of Genetics. This quiz covers the topics discussed in the course, including the chromosomal basis of heredity, gene segregation, and DNA. Prepare to assess your knowledge and ensure you grasp the fundamental principles of genetics.