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Questions and Answers
Which process is responsible for the increase in antibody affinity after prolonged exposure to an antigen?
Which process is responsible for the increase in antibody affinity after prolonged exposure to an antigen?
- Isotype switching
- Germinal center formation
- Affinity maturation (correct)
- Somatic hypermutation
Which type of antigens does affinity maturation occur in response to?
Which type of antigens does affinity maturation occur in response to?
- Protein antigens (correct)
- Carbohydrate antigens
- Lipid antigens
- DNA antigens
Which cells are critical in the process of affinity maturation?
Which cells are critical in the process of affinity maturation?
- Helper T cells (correct)
- Plasma cells
- B cells
- T cells
Which of the following is true about somatic hypermutation in germinal center B cells?
Which of the following is true about somatic hypermutation in germinal center B cells?
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Which of the following is true about the frequency of Ig gene mutations compared to other genes?
Which of the following is true about the frequency of Ig gene mutations compared to other genes?
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What happens to germinal center B cells that do not undergo somatic hypermutation?
What happens to germinal center B cells that do not undergo somatic hypermutation?
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What is the role of follicular dendritic cells (FDCs) in the selection of B cells in germinal centers?
What is the role of follicular dendritic cells (FDCs) in the selection of B cells in germinal centers?
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