Mastering T Cell-Mediated Immunity

Which type of antigens require T helper cell interaction to produce a B cell humoral response?

What is the main difference between T cell dependent and T cell independent responses?

What is the process by which antibodies improve their ability to bind to antigens with time and subsequent interactions with antigen?

What type of antigens do not consist of a large number of very similar or identical epitopes?

What determines the properties of a protein?

What is the role of T helper cells in the activation of B cells?

Where does the process of positive selection for strong antibody binding B cells occur?

What type of cells are plasma cells?

What is the result of class switching in antibodies?

What is the process by which B cells undergo further differentiation and antibody production?

Which cells produce antibodies in the parafollicular region?

What is the specialized structure produced after maturation of B cells within the follicle?

What are the processes that occur in the germinal center during B cell maturation?

What is the function of IgA immunoglobulin?

What is affinity maturation?

Which cells bind small amounts of antigen within the germinal center?

Where do some of the antibody secreting cells of the germinal center migrate to?

What do memory B cells do?

How frequent is somatic mutation in the variable region genes compared to nonvariable region genes?

What is the result of the competition between mutated B cells in the germinal center?

Which type of immunity relies on close-range interactions between immune effector T cells and the target?

What is the main function of cytotoxic lymphocytes in T cell-mediated immunity?

Which type of immunity is most effective against extracellular pathogens?

What type of antigens do B cells respond to in a T cell independent manner?

What is the main characteristic of T cell independent antigens?

What is the role of cytokines in T cell-mediated immunity?

What is the main function of immunoglobulin molecules in humoral immunity?

What type of antigens do T cells respond to?

What is the main function of B cells in the immune response?

How do humoral immunity and cell-mediated immunity differ?

Which immunoglobulin molecule is usually a cluster of five individual units?

Which region of an antibody molecule is quite flexible, allowing the variable end to adapt to the configuration of the antigen?

Which fragment of an immunoglobulin molecule consists of a light chain and the associated part of the heavy chain?

Which immunoglobulin molecule is present in secretions from the respiratory, gastrointestinal, and genitourinary mucosa?

Which immunoglobulin molecule plays a role in defense against parasites and provoking certain forms of allergy?

Which immunoglobulin molecule is the principal type formed in response to the majority of infectious agents?

Which immunoglobulin molecule is the first antibody to be synthesized in a primary immune response?

Which immunoglobulin molecule is efficient in combining with large particulate antigens such as fungi?

Which immunoglobulin molecule binds specifically to mast cells and plays a role in defense against parasites and provoking certain forms of allergy?

Which immunoglobulin molecule is normally present in only small quantities in the blood of most people, but greatly increased in allergic individuals?

Which of the following is NOT one of the five classes of immunoglobulin in humans?

Which classes of immunoglobulin in humans are further divided into subclasses?

What determines the specific effector function of an antibody?

What confers specificity of an antibody for a given antigen?

What is the term for antibodies produced by a large number of individual clones of B cells?

Under what condition may antibodies be monoclonal antibodies?

What is the term for the ability to produce monoclonal antibodies to desired antigens at will?

What is the most common method for producing monoclonal antibodies?

What is the term for the structure produced after maturation of B cells within the follicle?

What is the main function of cytotoxic lymphocytes in T cell-mediated immunity?

Which immunoglobulin molecule is usually a pair of units?

What is the main function of IgA immunoglobulin?

Which immunoglobulin molecule is normally present in only small quantities in the blood of most people, but greatly increased in allergic individuals?

What is the result of treatment with enzymes on an immunoglobulin molecule?

Which immunoglobulin molecule is the first antibody to be synthesized in a primary immune response?

Which type of immunity is IgG the principal type of antibody molecule formed in response to?

What is the main function of cytotoxic lymphocytes in T cell-mediated immunity?

What is the main function of B cells in the immune response?

What is the main difference between T cell dependent and T cell independent responses?

What is the term for the ability to produce monoclonal antibodies to desired antigens at will?

Which of the following is NOT one of the five classes of immunoglobulin in humans?

What is the main function of B cells in the immune response?

What determines the specific effector function of an antibody?

Which immunoglobulin molecule is present in secretions from the respiratory, gastrointestinal, and genitourinary mucosa?

Which immunoglobulin molecule is usually a cluster of five individual units?

What confers specificity of an antibody for a given antigen?

Which classes of immunoglobulin in humans are further divided into subclasses?

What do memory B cells do?

Under what condition may antibodies be monoclonal antibodies?

What type of antigens do not consist of a large number of very similar or identical epitopes?

Which of the following is NOT one of the five classes of immunoglobulin in humans?

Which immunoglobulin molecule is normally present in only small quantities in the blood of most people, but greatly increased in allergic individuals?

What is the main function of B cells in the immune response?

Which immunoglobulin molecule is the first antibody to be synthesized in a primary immune response?

What is the main function of B cells in the immune response?

Which immunoglobulin molecule is efficient in combining with large particulate antigens such as fungi?

Which immunoglobulin molecule is the principal type formed in response to the majority of infectious agents?

Which system of soluble proteins plays a critical role in self-defense?

Which pathway of complement activation is triggered by antigen-antibody interactions?

Which immunoglobulin antibodies are most efficient in activating complement?

Which autoimmune disease is associated with a specific form of postsynthetic protein modification that forms citrullinated peptides?

What is the main factor that contributes to the association of a particular class II HLA allele with an autoimmune disease?

What is a risk factor for severe rheumatoid arthritis and is also responsible for the production of citrullinated peptides in the lung?

Which type of immune response are many (but not all) of the genes involved in propensity for, particularly autoimmune response, related to?

Which diseases tend to have an autoimmune component and are associated with certain class II HLA types?

Which proteins fall into the two major groups within the HLA system?

Which genes control the class I proteins within the HLA system?

How many different allelic genes can occupy the gene loci within the HLA system?

Which HLA type is associated with a particular type of arthritis of the spine and the sacroiliac joints?

What does the presence of the HLA-B27 type indicate in relation to ankylosing spondylitis?