Advantages and Disadvantages of Parenteral Nutrition
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Questions and Answers

What is one advantage of providing drugs via parenteral administration?

  • To promote local anesthesia
  • To avoid systemic toxic effects (correct)
  • To cause rapid drug metabolism
  • To enhance gastrointestinal absorption
  • Which type of drug administration is suitable for drugs that are inactivated in the gastrointestinal tract?

  • Intravenous administration (correct)
  • Intramuscular administration
  • Oral administration
  • Subcutaneous administration
  • What is a disadvantage of parental administration of drugs?

  • Ease of countering incorrect drug dosage
  • Restriction to hospitals or specialized persons (correct)
  • Simple manufacturing process
  • Minimal pain and discomfort during injections
  • Why can some new drugs only be given via parenteral administration?

    <p>To avoid inactivation in the gastrointestinal tract</p> Signup and view all the answers

    What potential harm can occur if parenteral administration is not performed correctly?

    <p>Damage to nerves, muscles, and vasculature</p> Signup and view all the answers

    Which route of parenteral administration involves injecting into the vein?

    <p>Intravenous (IV)</p> Signup and view all the answers

    What volume range is suitable for IV infusion of large volume fluids according to the text?

    <p>100-1000 ml</p> Signup and view all the answers

    Which type of injections cannot be administered through the parenteral route?

    <p>Oily injections</p> Signup and view all the answers

    What is a potential consequence of administering drugs too quickly through IV infusion?

    <p>Increased drug-induced shock risk</p> Signup and view all the answers

    Where are IM injections usually given according to the text?

    <p>Thigh</p> Signup and view all the answers

    Which type of dosage forms are often combined for administration as an IV admixture?

    <p>Fluids and electrolytes</p> Signup and view all the answers

    What is a key feature of IM injections in terms of injection volume?

    <p>1-3 ml or up to 10 ml in divided doses</p> Signup and view all the answers

    What is the purpose of preservatives in pharmaceutical formulations?

    <p>To inhibit the growth of microorganisms</p> Signup and view all the answers

    Why must large volume parenteral formulations not contain preservatives?

    <p>Preservatives may be harmful to the human body in high doses</p> Signup and view all the answers

    How can partitioning into a micellar or oil phase affect the effectiveness of a preservative?

    <p>It decreases the preservative concentration</p> Signup and view all the answers

    What is the main function of antioxidants in pharmaceutical products?

    <p>To inhibit oxidative chain reactions</p> Signup and view all the answers

    How do certain antioxidants act as synergistic?

    <p>By increasing the effectiveness of other antioxidants</p> Signup and view all the answers

    What is the purpose of antioxidants forming complexes with catalysts in pharmaceutical products?

    <p>To slow down reactions</p> Signup and view all the answers

    What type of rubber stock is used with rubber stoppered products that are sensitive to oxygen?

    <p>Butyl rubber</p> Signup and view all the answers

    Why are stabilizers used in formulations?

    <p>To stabilize the formulation</p> Signup and view all the answers

    Which agents are commonly used to adjust isotonicity of IV solutions?

    <p>Dextrose, sodium chloride, potassium chloride</p> Signup and view all the answers

    What do solubilizing agents do in pharmaceutical formulations?

    <p>Increase the solubility of drugs</p> Signup and view all the answers

    Which information is required to be included in the labeling of a pharmaceutical product?

    <p>Manufacturer/Distributor details and expiration date</p> Signup and view all the answers

    Why are glass-seal ampules preferred for gas-sensitive products?

    <p>They provide the most impervious barrier for gas transmission</p> Signup and view all the answers

    What is the purpose of sterile water for injection containing pyrogen?

    <p>To prevent growth of potentially contaminating bacteria</p> Signup and view all the answers

    Why can't one-liter bottles of sterile water for injection be administered intravenously (IV)?

    <p>They have no tonicity</p> Signup and view all the answers

    What is the function of benzyl alcohol in sterile water for injection?

    <p>To suppress the growth of contaminating bacteria</p> Signup and view all the answers

    How is bacteriostatic water for injection different from sterile water for injection?

    <p>It contains a bacteriostatic agent</p> Signup and view all the answers

    Why should boiling water used for bacteriostatic water be stored to prevent reabsorption of oxygen?

    <p>To maintain its bacteriostatic properties</p> Signup and view all the answers

    What type of containers is sterile water containing 0.9% benzyl alcohol usually packaged in?

    <p>Prefilled syringes</p> Signup and view all the answers

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