Adrenocortical Function Disorders

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Questions and Answers

What is Cushing's syndrome characterized by?

  • Increased secretion of ACTH by the pituitary gland
  • Hyposecretion of glucocorticoids by the adrenal glands
  • Decreased glucocorticoid secretion by the adrenal cortex
  • Excessive glucocorticoid production by the adrenal cortex (correct)

What is the underlying cause of Cushing's disease?

  • Adenoma in the adrenal cortex
  • Hypersecretion of glucocorticoids by the adrenal glands
  • Hyposecretion of ACTH by the pituitary gland
  • Pituitary adenoma affecting ACTH secretion (correct)

What is the primary difference between Cushing's disease and Cushing's syndrome?

  • Cushing's disease affects the pituitary gland, while Cushing's syndrome affects the adrenal glands
  • Cushing's disease is characterized by decreased glucocorticoid secretion, while Cushing's syndrome is characterized by increased secretion
  • Cushing's disease affects the adrenal glands, while Cushing's syndrome affects the pituitary gland
  • Cushing's disease is caused by a pituitary adenoma, while Cushing's syndrome is caused by an adrenal adenoma (correct)

What is the effect of a pituitary adenoma on ACTH secretion?

<p>Increased ACTH secretion (A)</p> Signup and view all the answers

What is the most common cause of ACTH-dependent Cushing's syndrome?

<p>Pituitary adenoma secreting ACTH (D)</p> Signup and view all the answers

What percentage of Cushing's endogenous syndrome is ACTH-dependent?

<p>80% (A)</p> Signup and view all the answers

What is the role of the adrenal cortex in Cushing's syndrome?

<p>It produces more glucocorticoids in response to excessive ACTH (A)</p> Signup and view all the answers

What is the characteristic hormone profile in non-ACTH-dependent Cushing's syndrome?

<p>↓ACTH, ↑Cortisol (C)</p> Signup and view all the answers

What is the underlying cause of exogenous Cushing's syndrome?

<p>Prolonged administration of drugs (A)</p> Signup and view all the answers

What is the approximate percentage of non-ACTH-dependent Cushing's syndrome?

<p>20% (A)</p> Signup and view all the answers

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