Adrenocortical Function Disorders
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Questions and Answers

What is Cushing's syndrome characterized by?

  • Increased secretion of ACTH by the pituitary gland
  • Hyposecretion of glucocorticoids by the adrenal glands
  • Decreased glucocorticoid secretion by the adrenal cortex
  • Excessive glucocorticoid production by the adrenal cortex (correct)

    • What is the underlying cause of Cushing's disease?

  • Adenoma in the adrenal cortex
  • Hypersecretion of glucocorticoids by the adrenal glands
  • Hyposecretion of ACTH by the pituitary gland
  • Pituitary adenoma affecting ACTH secretion (correct)

    • What is the primary difference between Cushing's disease and Cushing's syndrome?

  • Cushing's disease affects the pituitary gland, while Cushing's syndrome affects the adrenal glands
  • Cushing's disease is characterized by decreased glucocorticoid secretion, while Cushing's syndrome is characterized by increased secretion
  • Cushing's disease affects the adrenal glands, while Cushing's syndrome affects the pituitary gland
  • Cushing's disease is caused by a pituitary adenoma, while Cushing's syndrome is caused by an adrenal adenoma (correct)

    • What is the effect of a pituitary adenoma on ACTH secretion?

    <p>Increased ACTH secretion</p> Signup and view all the answers

    What is the most common cause of ACTH-dependent Cushing's syndrome?

    <p>Pituitary adenoma secreting ACTH</p> Signup and view all the answers

    What percentage of Cushing's endogenous syndrome is ACTH-dependent?

    <p>80%</p> Signup and view all the answers

    What is the role of the adrenal cortex in Cushing's syndrome?

    <p>It produces more glucocorticoids in response to excessive ACTH</p> Signup and view all the answers

    What is the characteristic hormone profile in non-ACTH-dependent Cushing's syndrome?

    <p>↓ACTH, ↑Cortisol</p> Signup and view all the answers

    What is the underlying cause of exogenous Cushing's syndrome?

    <p>Prolonged administration of drugs</p> Signup and view all the answers

    What is the approximate percentage of non-ACTH-dependent Cushing's syndrome?

    <p>20%</p> Signup and view all the answers

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