10 Questions
What is Cushing's syndrome characterized by?
Excessive glucocorticoid production by the adrenal cortex
What is the underlying cause of Cushing's disease?
Pituitary adenoma affecting ACTH secretion
What is the primary difference between Cushing's disease and Cushing's syndrome?
Cushing's disease is caused by a pituitary adenoma, while Cushing's syndrome is caused by an adrenal adenoma
What is the effect of a pituitary adenoma on ACTH secretion?
Increased ACTH secretion
What is the most common cause of ACTH-dependent Cushing's syndrome?
Pituitary adenoma secreting ACTH
What percentage of Cushing's endogenous syndrome is ACTH-dependent?
80%
What is the role of the adrenal cortex in Cushing's syndrome?
It produces more glucocorticoids in response to excessive ACTH
What is the characteristic hormone profile in non-ACTH-dependent Cushing's syndrome?
↓ACTH, ↑Cortisol
What is the underlying cause of exogenous Cushing's syndrome?
Prolonged administration of drugs
What is the approximate percentage of non-ACTH-dependent Cushing's syndrome?
20%
Test your knowledge of disorders related to the adrenal cortex, including Cushing's disease and Cushing's syndrome, and their effects on the body. Learn about the causes and effects of hyperactivity in the adrenal gland.
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