Adrenergic Receptors Quiz

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Questions and Answers

Which type of receptor is coupled to activation of adenylyl cyclase?

  • Neither α- nor β-adrenergic receptors
  • Both α- and β-adrenergic receptors
  • α-adrenergic receptors
  • β-adrenergic receptors (correct)

What enzyme is activated by DAG binding?

  • Protein kinase C (correct)
  • Glycogen synthase
  • Phospholipase C
  • Adenylyl cyclase

What are the products of PIP2 hydrolysis by PLC?

  • Diacylglycerol (DAG)
  • Ca2+ ions
  • Inositol trisphosphate (IP3) (correct)
  • Phosphorylase kinase

What binds to receptors on the surface of the endoplasmic reticulum, leading to the release of Ca2+ ions?

<p>IP3 (D)</p> Signup and view all the answers

What subunits of phosphorylase kinase interact with Ca2+ ions and cause its activation?

<p>Calmodulin subunits (C)</p> Signup and view all the answers

What is the function of protein kinase C (PKC)?

<p>Phosphorylation of glycogen synthase (D)</p> Signup and view all the answers

Which G-proteins are α-adrenergic receptors coupled through?

<p>Gαs (B)</p> Signup and view all the answers

What is the role of Ca2+ ions in conjunction with DAG?

<p>Activate PKC (A)</p> Signup and view all the answers

What is the function of inositol trisphosphate (IP3)?

<p>Bind to receptors on the surface of the endoplasmic reticulum (B)</p> Signup and view all the answers

What enzyme is phosphorylated by PKC?

<p>Glycogen synthase (A)</p> Signup and view all the answers

What is the function of phospholipase C (PLC)?

<p>Hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) (C)</p> Signup and view all the answers

Which type of receptor is coupled to activation of adenylyl cyclase?

<p>β-adrenergic receptors (C)</p> Signup and view all the answers

What enzyme is activated by DAG binding?

<p>Protein kinase C (B)</p> Signup and view all the answers

What is the product of PIP2 hydrolysis by PLC?

<p>Inositol trisphosphate (IP3) (A)</p> Signup and view all the answers

What binds to receptors on the surface of the endoplasmic reticulum, leading to the release of Ca2+ ions?

<p>IP3 (C)</p> Signup and view all the answers

What subunits of phosphorylase kinase are activated by Ca2+ ions?

<p>Calmodulin subunits (A)</p> Signup and view all the answers

What is the function of protein kinase C (PKC)?

<p>Phosphorylation of glycogen synthase (C)</p> Signup and view all the answers

Which G-proteins are α-adrenergic receptors coupled through?

<p>Gαq/11 (A)</p> Signup and view all the answers

What is the role of Ca2+ ions in conjunction with DAG?

<p>Activate PKC (C)</p> Signup and view all the answers

What is the function of inositol trisphosphate (IP3)?

<p>Bind to receptors on the surface of the endoplasmic reticulum (B)</p> Signup and view all the answers

What is the product of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis by PLC?

<p>Diacylglycerol (DAG) (A)</p> Signup and view all the answers

What enzyme is phosphorylated by PKC?

<p>Glycogen synthase (A)</p> Signup and view all the answers

What is the function of phospholipase C (PLC)?

<p>Hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) (C)</p> Signup and view all the answers

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