Adrenergic Receptors Quiz
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Questions and Answers

Which type of receptor is coupled to activation of adenylyl cyclase?

  • Neither α- nor β-adrenergic receptors
  • Both α- and β-adrenergic receptors
  • α-adrenergic receptors
  • β-adrenergic receptors (correct)

    • What enzyme is activated by DAG binding?

  • Protein kinase C (correct)
  • Glycogen synthase
  • Phospholipase C
  • Adenylyl cyclase

    • What are the products of PIP2 hydrolysis by PLC?

  • Diacylglycerol (DAG)
  • Ca2+ ions
  • Inositol trisphosphate (IP3) (correct)
  • Phosphorylase kinase

    • What binds to receptors on the surface of the endoplasmic reticulum, leading to the release of Ca2+ ions?

    <p>IP3</p> Signup and view all the answers

    What subunits of phosphorylase kinase interact with Ca2+ ions and cause its activation?

    <p>Calmodulin subunits</p> Signup and view all the answers

    What is the function of protein kinase C (PKC)?

    <p>Phosphorylation of glycogen synthase</p> Signup and view all the answers

    Which G-proteins are α-adrenergic receptors coupled through?

    <p>Gαs</p> Signup and view all the answers

    What is the role of Ca2+ ions in conjunction with DAG?

    <p>Activate PKC</p> Signup and view all the answers

    What is the function of inositol trisphosphate (IP3)?

    <p>Bind to receptors on the surface of the endoplasmic reticulum</p> Signup and view all the answers

    What enzyme is phosphorylated by PKC?

    <p>Glycogen synthase</p> Signup and view all the answers

    What is the function of phospholipase C (PLC)?

    <p>Hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2)</p> Signup and view all the answers

    Which type of receptor is coupled to activation of adenylyl cyclase?

    <p>β-adrenergic receptors</p> Signup and view all the answers

    What enzyme is activated by DAG binding?

    <p>Protein kinase C</p> Signup and view all the answers

    What is the product of PIP2 hydrolysis by PLC?

    <p>Inositol trisphosphate (IP3)</p> Signup and view all the answers

    What binds to receptors on the surface of the endoplasmic reticulum, leading to the release of Ca2+ ions?

    <p>IP3</p> Signup and view all the answers

    What subunits of phosphorylase kinase are activated by Ca2+ ions?

    <p>Calmodulin subunits</p> Signup and view all the answers

    What is the function of protein kinase C (PKC)?

    <p>Phosphorylation of glycogen synthase</p> Signup and view all the answers

    Which G-proteins are α-adrenergic receptors coupled through?

    <p>Gαq/11</p> Signup and view all the answers

    What is the role of Ca2+ ions in conjunction with DAG?

    <p>Activate PKC</p> Signup and view all the answers

    What is the function of inositol trisphosphate (IP3)?

    <p>Bind to receptors on the surface of the endoplasmic reticulum</p> Signup and view all the answers

    What is the product of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis by PLC?

    <p>Diacylglycerol (DAG)</p> Signup and view all the answers

    What enzyme is phosphorylated by PKC?

    <p>Glycogen synthase</p> Signup and view all the answers

    What is the function of phospholipase C (PLC)?

    <p>Hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2)</p> Signup and view all the answers

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