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Questions and Answers
Which type of receptor is coupled to activation of adenylyl cyclase?
Which type of receptor is coupled to activation of adenylyl cyclase?
- α-adrenergic receptors
- None of the above
- Both α- and β-adrenergic receptors
- β-adrenergic receptors (correct)
What is the enzyme that is activated by DAG?
What is the enzyme that is activated by DAG?
- Phosphorylase kinase
- Phospholipase C
- Protein kinase C (correct)
- Adenylyl cyclase
What are the products of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2)?
What are the products of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2)?
- Adenylyl cyclase and phosphorylase kinase
- Calmodulin and Ca2+ ions
- Inositol trisphosphate (IP3) and diacylglycerol (DAG) (correct)
- Phospholipase C and protein kinase C
What is the role of IP3 in the activation of phosphorylase kinase?
What is the role of IP3 in the activation of phosphorylase kinase?
What is the enzyme that phosphorylates numerous substrates, including glycogen synthase?
What is the enzyme that phosphorylates numerous substrates, including glycogen synthase?
What is the role of Ca2+ ions in the activation of phosphorylase kinase?
What is the role of Ca2+ ions in the activation of phosphorylase kinase?
What is the role of PLC in the activation of α-adrenergic receptors?
What is the role of PLC in the activation of α-adrenergic receptors?
What is the role of DAG in the activation of PKC?
What is the role of DAG in the activation of PKC?
What is the role of IP3 in the release of Ca2+ ions?
What is the role of IP3 in the release of Ca2+ ions?
Which enzyme is activated by Ca2+ ions in conjunction with DAG?
Which enzyme is activated by Ca2+ ions in conjunction with DAG?
What is the product of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) that interacts with the calmodulin subunits of phosphorylase kinase?
What is the product of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) that interacts with the calmodulin subunits of phosphorylase kinase?
Which type of receptor is coupled through G-proteins that activate phospholipase C (PLC)?
Which type of receptor is coupled through G-proteins that activate phospholipase C (PLC)?
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