12 Questions
Which type of receptor is coupled to activation of adenylyl cyclase?
β-adrenergic receptors
What is the enzyme that is activated by DAG?
Protein kinase C
What are the products of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2)?
Inositol trisphosphate (IP3) and diacylglycerol (DAG)
What is the role of IP3 in the activation of phosphorylase kinase?
IP3 binds to receptors on the surface of the endoplasmic reticulum leading to the release of Ca2+ ions
What is the enzyme that phosphorylates numerous substrates, including glycogen synthase?
Protein kinase C
What is the role of Ca2+ ions in the activation of phosphorylase kinase?
Ca2+ ions interact with the calmodulin subunits of phosphorylase kinase resulting in its activation
What is the role of PLC in the activation of α-adrenergic receptors?
PLC hydrolyzes membrane phosphatidylinositol 4,5-bisphosphate (PIP2)
What is the role of DAG in the activation of PKC?
DAG binds to and activates PKC
What is the role of IP3 in the release of Ca2+ ions?
IP3 binds to and activates receptors on the surface of the endoplasmic reticulum
Which enzyme is activated by Ca2+ ions in conjunction with DAG?
Protein kinase C
What is the product of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) that interacts with the calmodulin subunits of phosphorylase kinase?
Ca2+ ions
Which type of receptor is coupled through G-proteins that activate phospholipase C (PLC)?
α-adrenergic receptors
Test your knowledge of β-adrenergic and α-adrenergic receptors in this quiz! Learn about the differences between these two receptor types and their coupling mechanisms, including the activation of adenylyl cyclase and phospholipase C. Discover the effects of increased hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate and the products of inositol trisphosphate and diacylglycerol. Perfect for students of pharmacology or
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