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Adrenergic Receptors Quiz

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Questions and Answers

Which type of receptor is coupled to activation of adenylyl cyclase?

α-adrenergic receptors

None of the above

Both α- and β-adrenergic receptors

β-adrenergic receptors (correct)

What is the enzyme that is activated by DAG?

Phosphorylase kinase

Phospholipase C

Protein kinase C (correct)

Adenylyl cyclase

What are the products of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2)?

Adenylyl cyclase and phosphorylase kinase

Calmodulin and Ca2+ ions

Inositol trisphosphate (IP3) and diacylglycerol (DAG) (correct)

Phospholipase C and protein kinase C

What is the role of IP3 in the activation of phosphorylase kinase?

IP3 binds to receptors on the surface of the endoplasmic reticulum leading to the release of Ca2+ ions (B) Signup and view all the answers

What is the enzyme that phosphorylates numerous substrates, including glycogen synthase?

Protein kinase C (C) Signup and view all the answers

What is the role of Ca2+ ions in the activation of phosphorylase kinase?

Ca2+ ions interact with the calmodulin subunits of phosphorylase kinase resulting in its activation (A) Signup and view all the answers

What is the role of PLC in the activation of α-adrenergic receptors?

PLC hydrolyzes membrane phosphatidylinositol 4,5-bisphosphate (PIP2) (D) Signup and view all the answers

What is the role of DAG in the activation of PKC?

DAG binds to and activates PKC (C) Signup and view all the answers

What is the role of IP3 in the release of Ca2+ ions?

IP3 binds to and activates receptors on the surface of the endoplasmic reticulum (D) Signup and view all the answers

Which enzyme is activated by Ca2+ ions in conjunction with DAG?

Protein kinase C (C) Signup and view all the answers

What is the product of the hydrolysis of membrane phosphatidylinositol 4,5-bisphosphate (PIP2) that interacts with the calmodulin subunits of phosphorylase kinase?

Ca2+ ions (D) Signup and view all the answers

Which type of receptor is coupled through G-proteins that activate phospholipase C (PLC)?

α-adrenergic receptors (B) Signup and view all the answers