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Questions and Answers
Which medication is an alpha 1 antagonist and a weak beta 1 antagonist?
Which medication is used for the palliative treatment of benign prostatic hypertrophy?
Which medication is an adrenergic neuron blocker used in the treatment of hypertension and vasospastic diseases?
Which medication inhibits adrenergic mediator release by reducing noradrenaline, dopamine, and serotonin synthesis?
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Which drug can cause postural hypotension as a significant effect?
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Which type of adrenergic receptor blockers can generate postural hypotension?
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Which drug has no significant effect on the heart but can increase sympathetic activity?
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Which adrenergic receptor blocker can cause myosis and block pilomotor contraction?
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Which drug can reverse the effect of adrenaline (α and β)?
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Which drug reduces kidney blood flow and causes water and salt retention?
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Which type of adrenergic receptor blockers removes sympathetic tone and vasodilates in vascular beds?
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Which drug blocks the secretion of apocrine sweat glands?
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Which type of blocker is phenoxybenzamine?
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What is the clinical use of dihydroergotamin maleate?
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What are the side effects and contraindications of ergot alkaloids?
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What are the clinical uses of prazosin and its analogues?
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What are the pharmacological effects of ergot alkaloids?
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What are the clinical uses of ergotamine tartrate?
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What is the pharmacological effect of labetolol?
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What are the side effects of prazosin and similar alpha blockers?
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What type of blocker is carvedilol?
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What are the clinical uses of dihydroergotamin maleate?
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Which of the following is a side effect of prazosin and similar alpha blockers?
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Which medication is used for treating migraine attacks and is available in combination with caffeine?
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What is the pharmacological effect of labetolol?
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Which drug is an irreversible blocker of alpha adrenergic receptors?
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What are the clinical uses of dihydroergotamin maleate?
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Which drug has a stronger beta-blocker effect and is used in mild-severe hypertension?
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Which medication is a selective alpha 1 blocker used in hypertension and benign prostatic hypertrophy?
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Which drug is used for migraines that do not respond to analgesic drugs?
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Which drug causes chronic ergot poisoning (ergotism) as a side effect?
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Which medication should periodic eye examination be performed during treatment due to its collection in the choroidal layer?
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Which drug can cause myosis and block pilomotor contraction?
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Which medication is an alpha 1 antagonist and a weak beta 1 antagonist?
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What type of adrenergic receptor blockers removes sympathetic tone and vasodilates in vascular beds?
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Which adrenergic receptor blocker can generate postural hypotension?
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What are the pharmacological effects of ergot alkaloids?
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What are the clinical uses of guanetidine and similar adrenergic neuron blockers?
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Which drug is an alpha 1 antagonist, weak alpha 2 agonist, and 5-HT1A-agonist, and also a weak beta1 antagonist?
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Which medication is used for the palliative treatment of benign prostatic hypertrophy?
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Which drug is an adrenergic neuron blocker used in the treatment of hypertension and vasospastic diseases?
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Which medication inhibits adrenergic mediator release by reducing noradrenaline, dopamine, and serotonin synthesis?
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Which drug is used in the treatment of pheochromocytoma or as premedication before surgery?
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Which drug is a 1 antagonist α haloperidol antipsychotic and an antagonist of dopamine?
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Which medication is used for the treatment of congestive heart failure (not preferred)?
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Which drug is used for the prevention of vasospasm in open heart and kidney transplant surgeries?
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Which medication is used for the treatment of peripheral vascular diseases due to sympathetic activity?
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Which drug is an alpha 1 antagonist used in the treatment of hypertension due to overdose of sympathomimetic drugs?
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Study Notes
Pharmacological Effects and Clinical Use of Alpha Adrenergic Blockers
- Phenoxybenzamine irreversibly blocks alpha adrenergic receptors and is not marketed in Turkey.
- Ergot alkaloids, found in ergot formed by the fungus Claviceps purpurea, have multiple pharmacological effects on smooth muscles, blood pressure, serotonin, and alpha-adrenergic receptors.
- Ergotamine tartrate is a powerful vasoconstrictor used for treating migraine attacks and is available in combination with caffeine.
- Dihydroergotamin maleate is used for migraines that do not respond to analgesic drugs and in the treatment of deep vein thrombosis.
- Side effects and contraindications of ergot alkaloids include nausea, vomiting, and can cause chronic ergot poisoning (ergotism).
- 3-Phentolamine and tolazoline are short-acting partial agonists on alpha-receptors.
- Prazosin and its analogues, such as terazosin and doxazosin, are selective alpha 1 blockers used in hypertension and benign prostatic hypertrophy.
- Prazosin causes hypotension, tolerance, and is also useful in congestive heart failure and Raynaud's syndrome.
- Labetolol is both an alpha and beta blocker, with a stronger beta-blocker effect, and is used in mild-severe hypertension.
- Carvedilol is another hybrid blocker with both alpha and beta-blocking effects.
- Prazosin and similar alpha blockers have side effects such as first-dose syncope and tachyphylaxis over time.
- Periodic eye examination should be performed during labetolol treatment due to its collection in the choroidal layer.
Pharmacological Effects and Clinical Use of Alpha Adrenergic Blockers
- Phenoxybenzamine irreversibly blocks alpha adrenergic receptors and is not marketed in Turkey.
- Ergot alkaloids, found in ergot formed by the fungus Claviceps purpurea, have multiple pharmacological effects on smooth muscles, blood pressure, serotonin, and alpha-adrenergic receptors.
- Ergotamine tartrate is a powerful vasoconstrictor used for treating migraine attacks and is available in combination with caffeine.
- Dihydroergotamin maleate is used for migraines that do not respond to analgesic drugs and in the treatment of deep vein thrombosis.
- Side effects and contraindications of ergot alkaloids include nausea, vomiting, and can cause chronic ergot poisoning (ergotism).
- 3-Phentolamine and tolazoline are short-acting partial agonists on alpha-receptors.
- Prazosin and its analogues, such as terazosin and doxazosin, are selective alpha 1 blockers used in hypertension and benign prostatic hypertrophy.
- Prazosin causes hypotension, tolerance, and is also useful in congestive heart failure and Raynaud's syndrome.
- Labetolol is both an alpha and beta blocker, with a stronger beta-blocker effect, and is used in mild-severe hypertension.
- Carvedilol is another hybrid blocker with both alpha and beta-blocking effects.
- Prazosin and similar alpha blockers have side effects such as first-dose syncope and tachyphylaxis over time.
- Periodic eye examination should be performed during labetolol treatment due to its collection in the choroidal layer.
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Description
Test your knowledge of adrenergic antagonist drugs and their classifications. Learn about alpha and beta adrenergic receptor blockers, as well as other sympatholytic drugs.
