16 Questions
What is the primary site of steroid production in the adrenal gland?
Outer cortex
What is the primary function of aldosterone?
Regulation of sodium and potassium levels
What is the percentage of cortisol that is bound to cortisol-binding globulin?
90-95%
What is the correct sequence of the adrenal cortex layers from outermost to innermost?
Zona glomerulosa, Zona fasciculata, Zona reticularis
What is the primary stimulus for cortisol production?
All of the above
What is the name of the hormone that exhibits negative feedback to the pituitary?
Cortisol
Which hormone is released by neurosecretory neurons into the anterior pituitary gland?
CRH
What is the effect of chronic cortisol release on the brain?
Atrophy of the hippocampus and depression
What is the effect of cortisol on adipose tissue?
Lipolysis
What is the characteristic finding in secondary hypocortisolism?
Absence of hyperpigmentation and decreased ACTH
What is the purpose of the ACTH stimulation test?
To diagnose primary adrenal insufficiency
What is the effect of cortisol on the thymus?
Inhibition of immune cell production
What is the cause of adrenal crisis?
All of the above
What is the effect of cortisol on the liver?
Increased gluconeogenesis
What is the effect of cortisol on skeletal muscles?
Increased proteolysis
What is the purpose of the Synacthen stimulation test?
To diagnose secondary adrenal insufficiency
Learn about the adrenal gland, its composition, and its functions. Discover the role of the cortex and medulla, and how they produce steroids and hormones.
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