Adrenal Gland Dysfunction

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What is the most common cause of Addison's disease in high-income countries?

  • Autoimmune destruction of adrenal cortical tissues (correct)
  • Hormonal imbalance
  • Infectious disease due to tuberculosis
  • Metastatic carcinoma

What is the effect of zona glomerulosa destruction on electrolyte levels?

  • No effect on electrolyte levels
  • Hypokalemia and hypernatremia
  • Hypernatremia and hypokalemia
  • Hyponatremia and hyperkalemia (correct)

Which of the following is a symptom of Addison's disease?

  • Cravings for salty food (correct)
  • Increased energy
  • Weight gain
  • Insomnia

What is the second most common cause of Addison's disease?

<p>Metastatic carcinoma (B)</p> Signup and view all the answers

What is the effect of adrenal cortex destruction on blood pressure?

<p>Hypotension (A)</p> Signup and view all the answers

In which layer of the adrenal cortex is aldosterone produced?

<p>Zona glomerulosa (A)</p> Signup and view all the answers

What is the most common cause of Addison's disease in countries where tuberculosis is prevalent?

<p>Infectious disease due to tuberculosis (C)</p> Signup and view all the answers

What is the genetic cause of Sturge-Weber Syndrome?

<p>Somatic mutations in the GNAQ gene (C)</p> Signup and view all the answers

What is a common symptom of Pheochromocytoma?

<p>Palpitations (C)</p> Signup and view all the answers

What is a possible complication of uncontrolled hypertension caused by Pheochromocytoma?

<p>Hemorrhage and ischemia (C)</p> Signup and view all the answers

What is the typical blood pressure threshold for hypertensive urgency?

<p>180/120 mmHg (B)</p> Signup and view all the answers

What is the name of the gene associated with Multiple Endocrine Neoplasia Type 2B?

<p>RET (D)</p> Signup and view all the answers

What is a common finding in patients with Pheochromocytoma?

<p>Mucosal neuromas (B)</p> Signup and view all the answers

What is a serious complication of Pheochromocytoma?

<p>Stroke (A)</p> Signup and view all the answers

What is the primary cause of primary adrenal insufficiency?

<p>Damage to the adrenal cortex (B)</p> Signup and view all the answers

What is the difference between acute and chronic primary adrenal insufficiency?

<p>Acute is Waterhouse-Friderichsen syndrome, while chronic is Addison disease (D)</p> Signup and view all the answers

What is the name of the syndrome caused by the progressive destruction of the adrenal gland?

<p>Addison disease (C)</p> Signup and view all the answers

What is the primary function of the adrenal gland?

<p>To produce hormones that regulate electrolyte balance (C)</p> Signup and view all the answers

What is the term for the group of disorders characterized by the excessive production of androgens?

<p>Androgenital syndromes (A)</p> Signup and view all the answers

What is the term for the tumor that arises from chromaffin cells?

<p>Pheochromocytoma (D)</p> Signup and view all the answers

What is the distinction between primary and secondary adrenal insufficiency?

<p>Primary is due to a problem localized to the adrenal gland, while secondary is due to a problem elsewhere in the body (C)</p> Signup and view all the answers

What is the primary method for diagnosing pheochromocytoma?

<p>Measuring catecholamines in blood or urine (C)</p> Signup and view all the answers

What is the treatment for a hypertensive crisis in pheochromocytoma?

<p>Medications to lower blood pressure that block alpha and beta receptors (C)</p> Signup and view all the answers

What is the age range of most neuroblastoma cases?

<p>Infants &lt; 5 years old (D)</p> Signup and view all the answers

What is the origin of neuroblastoma tumors?

<p>Neural crest cells in the adrenal medulla (D)</p> Signup and view all the answers

What are the two types of neuroblastoma cells?

<p>Undifferentiated and poorly differentiated (A)</p> Signup and view all the answers

What genetic mutation is associated with neuroblastoma?

<p>Mutation on the MYCN oncogene (D)</p> Signup and view all the answers

What is the result of neural crest cells failing to differentiate during fetal development?

<p>Formation of a tumor in the adrenal medulla (B)</p> Signup and view all the answers

What is the substance that surrounds cells with lots of cytoplasm in a neuroblastoma?

<p>Schwannian stroma (C)</p> Signup and view all the answers

What is the function of CXCL12 in the context of neuroblastoma?

<p>It attracts immune cells to the tumor site (B)</p> Signup and view all the answers

Where does CXCL12 reach after a neuroblastoma cell ruptures?

<p>The lymph nodes, liver, bones, and bone marrow (B)</p> Signup and view all the answers

What is the result of immune cells sensing high CXCL12 levels?

<p>They attack the lymph nodes, liver, bones, and bone marrow (D)</p> Signup and view all the answers

What is the characteristic of neuroblastoma cells?

<p>Lots of cytoplasm (D)</p> Signup and view all the answers

What is the network of nerve fibers that surrounds neuroblastoma cells?

<p>Neuropil (D)</p> Signup and view all the answers

What is the consequence of CXCL12 release into the bloodstream?

<p>Immune cells attack the lymph nodes, liver, bones, and bone marrow (B)</p> Signup and view all the answers

What is the role of CXCL12 in neuroblastoma pathogenesis?

<p>It is a pro-inflammatory marker (D)</p> Signup and view all the answers

Flashcards are hidden until you start studying

Related Documents

More Like This

Adrenal Gland Pathology Quiz
5 questions
Adrenal Gland Dysfunction
21 questions

Adrenal Gland Dysfunction

InspirationalFairy avatar
InspirationalFairy
Adrenal Gland Pathology Overview
29 questions
Use Quizgecko on...
Browser
Browser