Adherens Junctions in Cell Interactions
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Questions and Answers

What is the role of cadherins in adherens junctions?

  • Contracting actin filaments
  • Facilitating the formation of tight junctions
  • Serving as transmembrane adhesion proteins (correct)
  • Maintaining the integrity of intracellular anchor proteins

In epithelial cells, where do the adhesion belts typical of adherens junctions form?

  • Inside the cytoplasm
  • Around each interacting cell in the sheet (correct)
  • Just above the tight junctions
  • At the nucleus

How are the actin bundles linked within the extensive transcellular network in adherens junctions?

  • Via cadherins and anchor proteins (correct)
  • Via integrins
  • By desmosomes
  • Through gap junctions

What is the orientation of the contractile bundle of actin filaments relative to the plasma membrane in adherens junctions?

<p>Parallel (C)</p> Signup and view all the answers

What is the proposed role of the transcellular network in animal morphogenesis mentioned in the text?

<p>Mediating folding of epithelial cell sheets into tubes (B)</p> Signup and view all the answers

What is the primary function of adherens junctions in nonepithelial tissues?

<p>Directly connect the cortical actin filaments of two interacting cells (B)</p> Signup and view all the answers

What is the role of catenins, vinculin, and α-actinin in adherens junctions?

<p>Anchor the actin filaments to the plasma membrane (A)</p> Signup and view all the answers

How does the transcellular network in adherens junctions contract?

<p>With the help of myosin motor proteins (C)</p> Signup and view all the answers

Where do prototypical examples of adherens junctions typically occur?

<p>In epithelia as continuous adhesion belts below tight junctions (D)</p> Signup and view all the answers

What is the role of desmosomes in cells?

<p>Serve as anchoring sites for intermediate filaments (D)</p> Signup and view all the answers

Why do the particular type of intermediate filaments attached to desmosomes vary among cell types?

<p>Depending on the tissue, different types of intermediate filaments are needed (A)</p> Signup and view all the answers

How do desmosomes contribute to the overall structure of tissues?

<p>By forming a network that connects all cells within a tissue (D)</p> Signup and view all the answers

Flashcards

Cadherins' role in adherens junctions

Transmembrane adhesion proteins in adherens junctions

Adherens junction location in epithelial cells

Form adhesion belts around interacting cells in sheets

Actin bundles' link in adherens junctions

Linked by cadherins and anchor proteins

Actin filament orientation

Parallel to the plasma membrane in adherens junctions

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Transcellular network's role in morphogenesis

Mediates folding of epithelial cell sheets into tubes

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Adherens junctions in nonepithelial tissues

Directly connect cortical actin filaments

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Catenins, vinculin, α-actinin's role

Anchor actin filaments to plasma membrane

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Adherens junction contraction method

Myosin motor proteins

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Typical adherens junction location

Epithelia, below tight junctions

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Desmosomes' role

Anchor intermediate filaments

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Desmosome intermediate filament variability

Varies depending on tissue type

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Desmosomes' tissue structure contribution

Form a network connecting all tissue cells

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