Cell Adhesion Structures Quiz
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Questions and Answers

What is the primary function of zonula adherens in cellular structures?

  • Facilitates nutrient uptake
  • Provides mechanical stability (correct)
  • Acts as a selective barrier
  • Allows rapid communication between cells
  • Which protein complex is associated with cadherins in zonula adherens?

  • Catenin (correct)
  • Collagen
  • Integrin
  • Fibronectin
  • Which type of cell primarily contains fascia adherens?

  • Cardiac muscle cells (correct)
  • Epithelial cells
  • Connective tissue cells
  • Skin cells
  • What characterizes desmosomes in terms of structure?

    <p>They have attachment plaques containing desmoplakins and plakoglobins</p> Signup and view all the answers

    What role do intermediate filaments play in macula adherens (desmosome)?

    <p>They interact with desmoplakins and plakoglobins</p> Signup and view all the answers

    What is a defining physical characteristic of fascia adherens compared to zonula adherens?

    <p>It forms a sheet-like structure.</p> Signup and view all the answers

    Which protein is known to bind the cytoplasmic part of cadherin in zonula adherens?

    <p>Catenin</p> Signup and view all the answers

    What do desmoplakins and plakoglobins primarily contribute to in macula adherens?

    <p>They form attachment plaques.</p> Signup and view all the answers

    What is the mechanical role of zonula adherens in cellular structure?

    <p>It provides mechanical stability.</p> Signup and view all the answers

    Which type of junction does macula adherens primarily represent?

    <p>A spot-like junction</p> Signup and view all the answers

    Which of the following is true regarding the intermediate filaments in macula adherens?

    <p>They integrate into attachment plaques.</p> Signup and view all the answers

    What is the function of cadherins in zonula adherens?

    <p>They create a junction between membranes.</p> Signup and view all the answers

    The fuzzy plaque found in zonula adherens corresponds to which of the following?

    <p>Cadherin-catenin complex</p> Signup and view all the answers

    What distinguishes the intercellular space in macula adherens?

    <p>It displays an intermediate line.</p> Signup and view all the answers

    Which type of cells predominantly contain fascia adherens?

    <p>Cardiac muscle cells</p> Signup and view all the answers

    Study Notes

    Zonula Adherens

    • Provides mechanical stability to cells.
    • Forms a belt-like junction between adjacent cells.
    • The intercellular space contains extracellular portions of cadherin proteins.
    • Cadherin is a calcium-dependent transmembrane protein.
    • Intracellular protein, catenin, binds to the cytoplasmic part of cadherin, creating a complex.
    • The E-cadherin/catenin complex interacts with vinculin.
    • Vinculin interacts with alpha-actinin, linking to actin filaments.
    • A "fuzzy plaque" contains the cadherin/catenin complex, vinculin, and alpha-actinin at the cytoplasmic side, corresponding to a terminal bar at the light microscopic level.
    • Actin filaments are part of the terminal web.

    Fascia Adherens

    • Structure is sheet-like, not belt-like.
    • Found in non-epithelial cells, such as cardiac muscle cells.

    Macula Adherens (Desmosome)

    • Resists shearing forces and distributes physical forces within the cell.
    • Forms a spot-like junction.
    • Desmosomes have characteristic attachment plaques.
    • Desmoplakins and plakoglobins are key proteins within attachment plaques, which also contain cytoplasmic parts of desmogleins and desmocollins.
    • Intermediate filaments insert into attachment plaques, interacting with desmoplakins and plakoglobins, forming a loop and returning.
    • Desmoglein and desmocollin (cadherins) are transmembrane glycoproteins connecting the plasma membranes of adjacent cells.
    • The intercellular space shows a distinctive intermediate line, corresponding to the extracellular portions of desmoglein and desmocollin.

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    Description

    Test your knowledge on the various types of cell adhesion structures, including zonula adherens, fascia adherens, and macula adherens (desmosomes). This quiz covers the functions, locations, and characteristics of these critical cellular junctions. Perfect for students studying cell biology and physiology.

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