Adaptive Immune Response Quiz

Patients typically experience recurrent infections due to impaired antibody production.

B cells are responsible for producing antibodies that neutralize pathogens and mark them for destruction.

The main classes of antibodies are IgG, IgA, IgM, IgE, and IgD, each serving distinct functions in immune defense.

<p>Clonal selection is the process where specific B cells are activated by their corresponding antigen, leading to proliferation and differentiation.</p> Signup and view all the answers

<p>Immunological memory forms when some activated B cells differentiate into memory B cells, enabling a faster response upon re-exposure to the same antigen.</p> Signup and view all the answers

<p>Selective Immunoglobulin Deficiency leads to an increased susceptibility to recurrent respiratory infections due to inadequate antibody response.</p> Signup and view all the answers

<p>SCID is characterized by the absence of a functional immune system, making affected individuals extremely susceptible to infections.</p> Signup and view all the answers

<p>B cell malignancies, such as lymphomas, result in excessive and uncontrolled B cell proliferation, impairing the normal immune response.</p> Signup and view all the answers

<p>B-cells are responsible for producing antibodies that target specific antigens.</p> Signup and view all the answers

<p>The five classes are IgG (main immune response), IgA (mucosal immunity), IgM (first response), IgE (allergic responses), and IgD (B cell receptor).</p> Signup and view all the answers

<p>Clonal selection refers to the process by which specific B-cells are activated upon encountering their corresponding antigen, leading to proliferation and differentiation.</p> Signup and view all the answers

<p>The primary response occurs upon first exposure to an antigen, while the secondary response is faster and stronger due to immunological memory from prior exposure.</p> Signup and view all the answers

<p>T-cells assist B-cells by providing necessary signals through cytokines and interactions that enhance B-cell proliferation and antibody production.</p> Signup and view all the answers

<p>The clonal selection hypothesis states that each B cell with a unique BCR binds to a specific antigen, leading to the activation and proliferation of that particular clone.</p> Signup and view all the answers

<p>B cells are activated when their BCR binds an antigen and receive help from activated T cells, which provide necessary signals for proliferation and differentiation.</p> Signup and view all the answers

<p>After activation, B cells differentiate into plasma cells and memory B cells.</p> Signup and view all the answers

<p>Antibodies recognize and bind to specific antigens, neutralizing them and marking them for destruction by other immune cells.</p> Signup and view all the answers

<p>The secondary antibody response is faster and more specific compared to the primary response due to the presence of memory B cells that respond to previously encountered antigens.</p> Signup and view all the answers

<p>The nature of the original antigen and the overall immune response can influence how long immunological memory lasts.</p> Signup and view all the answers

<p>When a B cell binds to an antigen with its BCR, it undergoes activation, leading to clonal expansion and the generation of effector cells.</p> Signup and view all the answers

<p>Memory B cells are significant because they enable a quicker and more robust immune response upon re-exposure to the same antigen.</p> Signup and view all the answers

<p>Activation of B cells is fundamental to the humoral immune response, allowing the body to produce antibodies that target and eliminate pathogens.</p> Signup and view all the answers

<p>Sir Frank Macfarlane Burnet contributed by developing the clonal selection theory, which explains how specific B cells are selected and activated in response to infections.</p> Signup and view all the answers