Acute vs. Chronic Hepatitis Comparison

Acute vs. Chronic Hepatitis Comparison

Created by
@Same_Soup

Questions and Answers

Which enzyme is responsible for converting ethanol into acetaldehyde in the normal alcohol metabolism pathway?

Alcohol dehydrogenase (ADH)

What process leads to reversible steatosis (fat) in the liver with short-term ingestion of ethanol?

Fatty liver

Which of the following is a characteristic effect of alcohol metabolism in binge drinkers (>6 drinks)?

Production of ROS by CYP2E1 enzyme

Which condition usually requires daily ingestion of 80g or more of ethanol for 10-20 years to lead to severe hepatic injury?

<p>Alcoholic Liver Disease</p> Signup and view all the answers

What is the main reason for increased fat storage in the liver due to alcohol consumption?

<p>NAD+ reduction</p> Signup and view all the answers

Which protein aggregates are associated with Mallory-Denk bodies seen in alcoholic hepatitis?

<p>Keratin protein aggregates</p> Signup and view all the answers

What characteristic pattern does alcoholic steatofibrosis follow in the liver?

<p>Central-portal fibrous septa</p> Signup and view all the answers

"Laennec cirrhosis" is a term used specifically for cirrhosis due to which cause?

<p>Alcoholic Liver Disease</p> Signup and view all the answers

Which liver condition is characterized by fibrosis and conversion of the liver architecture into micro/macro nodules?

<p>Alcoholic liver disease</p> Signup and view all the answers

What is considered the gold standard for diagnosing liver diseases?

<p>Liver biopsy</p> Signup and view all the answers

What is the most common cause of chronic liver disease in the US?

<p>Metabolic syndrome</p> Signup and view all the answers

What is the main difference between Non-Alcoholic Fatty Liver Disease (NAFLD) and Alcoholic Liver Disease in terms of histological features?

<p>Steatosis</p> Signup and view all the answers

What causes the characteristic yellow, greasy appearance of liver lobes in individuals with NAFLD?

<p>Widespread steatosis</p> Signup and view all the answers

What initiates the degradation process of fat in hepatocytes leading to steatohepatitis?

<p>Hydroxyl radical</p> Signup and view all the answers

What histological feature differentiates NASH from alcoholic fatty liver disease?

<p>Steatosis &gt;5% of hepatocytes</p> Signup and view all the answers

'Neutrophilic infiltrate' is a characteristic feature associated with which type of liver disease?

<p>Non-alcoholic steatohepatitis</p> Signup and view all the answers

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