Podcast
Questions and Answers
Which enzyme is responsible for converting ethanol into acetaldehyde in the normal alcohol metabolism pathway?
Which enzyme is responsible for converting ethanol into acetaldehyde in the normal alcohol metabolism pathway?
- Acetaldehyde dehydrogenase (ALDH)
- H202/Catalase
- Alcohol dehydrogenase (ADH) (correct)
- CYP2E1 enzyme
What process leads to reversible steatosis (fat) in the liver with short-term ingestion of ethanol?
What process leads to reversible steatosis (fat) in the liver with short-term ingestion of ethanol?
- Acetaldehyde accumulation
- Fatty acid oxidation
- Fatty liver (correct)
- Mitosis cell regeneration
Which of the following is a characteristic effect of alcohol metabolism in binge drinkers (>6 drinks)?
Which of the following is a characteristic effect of alcohol metabolism in binge drinkers (>6 drinks)?
- Decreased perfusion of hepatocytes
- Activation of Acetyl-CoA synthesis pathway
- Reduction in NAD+ levels
- Production of ROS by CYP2E1 enzyme (correct)
Which condition usually requires daily ingestion of 80g or more of ethanol for 10-20 years to lead to severe hepatic injury?
Which condition usually requires daily ingestion of 80g or more of ethanol for 10-20 years to lead to severe hepatic injury?
What is the main reason for increased fat storage in the liver due to alcohol consumption?
What is the main reason for increased fat storage in the liver due to alcohol consumption?
Which protein aggregates are associated with Mallory-Denk bodies seen in alcoholic hepatitis?
Which protein aggregates are associated with Mallory-Denk bodies seen in alcoholic hepatitis?
What characteristic pattern does alcoholic steatofibrosis follow in the liver?
What characteristic pattern does alcoholic steatofibrosis follow in the liver?
"Laennec cirrhosis" is a term used specifically for cirrhosis due to which cause?
"Laennec cirrhosis" is a term used specifically for cirrhosis due to which cause?
Which liver condition is characterized by fibrosis and conversion of the liver architecture into micro/macro nodules?
Which liver condition is characterized by fibrosis and conversion of the liver architecture into micro/macro nodules?
What is considered the gold standard for diagnosing liver diseases?
What is considered the gold standard for diagnosing liver diseases?
What is the most common cause of chronic liver disease in the US?
What is the most common cause of chronic liver disease in the US?
What is the main difference between Non-Alcoholic Fatty Liver Disease (NAFLD) and Alcoholic Liver Disease in terms of histological features?
What is the main difference between Non-Alcoholic Fatty Liver Disease (NAFLD) and Alcoholic Liver Disease in terms of histological features?
What causes the characteristic yellow, greasy appearance of liver lobes in individuals with NAFLD?
What causes the characteristic yellow, greasy appearance of liver lobes in individuals with NAFLD?
What initiates the degradation process of fat in hepatocytes leading to steatohepatitis?
What initiates the degradation process of fat in hepatocytes leading to steatohepatitis?
What histological feature differentiates NASH from alcoholic fatty liver disease?
What histological feature differentiates NASH from alcoholic fatty liver disease?
'Neutrophilic infiltrate' is a characteristic feature associated with which type of liver disease?
'Neutrophilic infiltrate' is a characteristic feature associated with which type of liver disease?
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