Acute Myeloid Leukemia Histopathology

<p>It determines the diagnosis and classification of the disease</p> Signup and view all the answers

<p>It provides a comprehensive understanding of the disease</p> Signup and view all the answers

<p>To guide treatment decisions and predict patient outcomes</p> Signup and view all the answers

<p>To analyze the bone marrow for the presence of leukemic cells and other abnormalities</p> Signup and view all the answers

<p>To detect specific antigens on leukemic cells</p> Signup and view all the answers

<p>Diagnosis of myeloid neoplasms associated with myelofibrosis</p> Signup and view all the answers

<p>To identify the lineage of leukemic cells</p> Signup and view all the answers

<p>Immunohistochemistry can easily correlate with flow cytometry</p> Signup and view all the answers

<p>Gene expression profiling</p> Signup and view all the answers

<p>Immature, round or oval cells with a high nucleus-to-cytoplasm ratio, prominent nucleoli, and scant or absent cytoplasm.</p> Signup and view all the answers

<p>The presence of abnormal granules, such as Auer rods, is a hallmark feature of AML, particularly in cases with monocytic differentiation.</p> Signup and view all the answers

<p>Eight</p> Signup and view all the answers

<p>To aid in diagnosis and classification of AML through the examination of bone marrow tissue.</p> Signup and view all the answers

<p>To identify chromosomal abnormalities and aid in diagnosis and classification of AML.</p> Signup and view all the answers

<p>The FAB classification system categorizes AML into eight main subtypes based on morphology and clinical features.</p> Signup and view all the answers

<p>The morphology of blasts is significant in AML diagnosis as it helps in the classification of AML into different subtypes based on the morphological features of leukemic cells.</p> Signup and view all the answers

<p>The FAB classification system categorizes AML into eight subtypes based on the morphological features of leukemic cells.</p> Signup and view all the answers

<p>Abnormalities in chromosome number or structure, such as translocations, inversions, or deletions, are common in AML.</p> Signup and view all the answers

<p>Bone marrow biopsy is valuable in evaluating AML as it allows for the assessment of bone marrow architecture and the presence of blasts.</p> Signup and view all the answers

<p>The purpose of immunohistochemistry in bone marrow biopsy is to demonstrate pathological accumulations of blasts using markers such as CD34.</p> Signup and view all the answers

<p>The presence of reticulin fibrosis or fatty changes in the bone marrow can make accurate disease characterization difficult in certain cases.</p> Signup and view all the answers

<p>contractions</p> Signup and view all the answers

<p>protects the heart from outside forces</p> Signup and view all the answers

<p>receives blood from the body and returns it to the heart</p> Signup and view all the answers

<p>right side receives deoxygenated blood from the body, while the left side receives oxygen-rich blood from the lungs</p> Signup and view all the answers

<p>lines the heart's chambers and protects the valves</p> Signup and view all the answers

<p>near the center of the chest, in the mediastinal cavity of the thorax, between the lungs</p> Signup and view all the answers