Acute Interstitial Nephritis Causes and Symptoms
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Questions and Answers

What is the most common cause of drug-induced acute interstitial nephritis (AIN)?

  • Proton pump inhibitors (PPIs) (correct)
  • Beta blockers
  • Angiotensin-converting enzyme (ACE) inhibitors
  • Non-steroidal anti-inflammatory drugs (NSAIDs)

What is a common clinical feature of acute interstitial nephritis (AIN)?

  • Hematuria
  • Renal impairment (correct)
  • Proteinuria
  • Hypertension

What may be present in some patients with drug-induced acute interstitial nephritis (AIN)?

  • Signs of a generalised drug hypersensitivity reaction (correct)
  • Signs of a generalised bacterial infection
  • Signs of a generalised allergic reaction
  • Signs of a generalised viral infection

What is a possible complication of acute interstitial nephritis (AIN)?

<p>Systemic diseases and infections (C)</p> Signup and view all the answers

What is a possible laboratory finding in some patients with drug-induced acute interstitial nephritis (AIN)?

<p>Eosinophilia (D)</p> Signup and view all the answers

What percentage of patients are likely to have eosinophils?

<p>Up to 70% (A)</p> Signup and view all the answers

What can be said about the presence of eosinophils in patients?

<p>It is a non-specific finding (B)</p> Signup and view all the answers

What is the significance of eosinophils in patients?

<p>It is a non-specific indicator (D)</p> Signup and view all the answers

In what percentage of patients are eosinophils absent?

<p>At most 30% (B)</p> Signup and view all the answers

What can be inferred about the presence of eosinophils in patients?

<p>It is a non-specific finding (A)</p> Signup and view all the answers

What is the potential source of nephrotoxicity associated with herbal medicines in Asia?

<p>Herbal medicine ingredients (D)</p> Signup and view all the answers

Which populations are affected by Balkan nephropathy?

<p>Isolated rural communities in Eastern Europe (C)</p> Signup and view all the answers

What is the possible route of exposure to nephrotoxic substances in Balkan nephropathy?

<p>Consumption of contaminated food (D)</p> Signup and view all the answers

What is the geographic distribution of Balkan nephropathy?

<p>Isolated to rural communities in Eastern Europe (A)</p> Signup and view all the answers

What is the likely cause of nephrotoxicity associated with herbal medicines in Asia?

<p>Toxic compounds in herbal ingredients (D)</p> Signup and view all the answers

What may underlie many cases of CIN?

<p>Genetic causes (C)</p> Signup and view all the answers

Which plant has been associated with CIN due to toxin presence?

<p>Aristolochia clematitis (birthwort) (A)</p> Signup and view all the answers

What is a potential risk factor for developing CIN?

<p>Ingestion of Aristolochia clematitis toxins (C)</p> Signup and view all the answers

What is a possible underlying cause of CIN, according to research?

<p>Genetic mutations (B)</p> Signup and view all the answers

What is a potential source of toxins linked to CIN?

<p>Plant-based toxins (C)</p> Signup and view all the answers

What is a characteristic feature of salt-losing nephropathy?

<p>Hypotension (A)</p> Signup and view all the answers

Which of the following is NOT a feature of sodium and water depletion?

<p>Hypernatremia (C)</p> Signup and view all the answers

What is the primary cause of polyuria in salt-losing nephropathy?

<p>Sodium and water depletion (A)</p> Signup and view all the answers

Which of the following laboratory findings is LEAST likely to be associated with salt-losing nephropathy?

<p>Hyperkalemia (B)</p> Signup and view all the answers

What is the underlying pathophysiologic mechanism of salt-losing nephropathy?

<p>Renal tubular dysfunction (B)</p> Signup and view all the answers

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