Acute Cholecystitis and PC Overview
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Questions and Answers

What complication may cause persistent biliary leakage after the removal of a pigtail catheter?

  • Gallstone ileus
  • Hepatic abscess
  • Cholecystocutaneous fistula (correct)
  • Cholecystitis
  • Favorable clinical outcomes from PC procedures are reported in less than 90% of patients.

    False (B)

    What is the recommended procedure for managing abscess formation within the subcutaneous abdominal wall?

    Cholecystectomy with drainage of the collection.

    A significant bile leak can occur after the removal of a PC catheter, especially in cases involving an iatrogenic rent in the __________.

    <p>GB wall</p> Signup and view all the answers

    Match the following outcomes or procedures with their appropriate descriptions:

    <p>Cholecystectomy = Procedure to remove the gallbladder Biliary peritonitis = Complication from significant bile leaks Trans-peritoneal route = Common route with iatrogenic rent risks Tractogram = Assessment of cystic duct and CBD patency</p> Signup and view all the answers

    What is the primary management strategy for mild acute cholecystitis?

    <p>Medical therapy and early cholecystectomy (B)</p> Signup and view all the answers

    Acalculous cholecystitis is less common than calculous cholecystitis in critical illness settings.

    <p>False (B)</p> Signup and view all the answers

    What is percutaneous cholecystostomy primarily used for?

    <p>To drain the gallbladder in patients with moderate to severe acute cholecystitis.</p> Signup and view all the answers

    Acute cholecystitis (AC) can result from _____ and _____ as common predisposing factors.

    <p>gallstones, critical illnesses</p> Signup and view all the answers

    Match the following types of cholecystitis with their respective characteristics:

    <p>Calculous cholecystitis = Caused by gallstones Acalculous cholecystitis = No gallstones present Moderate acute cholecystitis = Grade II condition Severe acute cholecystitis = Grade III condition</p> Signup and view all the answers

    What is one of the primary purposes of percutaneous cholecystostomy?

    <p>To drain fluid from the gallbladder (A)</p> Signup and view all the answers

    Gallbladder empyema can be treated with ultrasonically guided percutaneous drainage.

    <p>True (A)</p> Signup and view all the answers

    What is the significance of understanding risk factors for perioperative complications in laparoscopic cholecystectomy?

    <p>It helps improve patient outcomes and reduce surgical risks.</p> Signup and view all the answers

    The first cholangio________ was Dr. John S. Bobbs.

    <p>ecystotomist</p> Signup and view all the answers

    Match the following studies with their focus:

    <p>Akhan O, Akinci D, Ozmen MN (2002) = Percutaneous cholecystostomy Sparkman RS (1967) = Cholangiography history Giger UF, Michel J-M (2006) = Risk factors for complications Duncan C et al (2016) = Cholecystostomy in the presence of ascites</p> Signup and view all the answers

    Which patient demographic is suggested to particularly benefit from percutaneous cholecystostomy (PC)?

    <p>Very elderly patients with acute cholecystitis (B)</p> Signup and view all the answers

    In which clinical setting is emergency bedside ultrasound-guided PC indicated?

    <p>Intensive care unit with acalculous acute cholecystitis (A)</p> Signup and view all the answers

    What factor increases the risk of developing acute cholecystitis in patients admitted to the ICU?

    <p>Prolonged stay in ICU due to poly-trauma (C)</p> Signup and view all the answers

    How might extensive burns affect the incidence of acute cholecystitis?

    <p>By causing severe dehydration and prolonged total parenteral nutrition (B)</p> Signup and view all the answers

    What is a significant underlying condition that may warrant the performance of percutaneous cholecystostomy?

    <p>Neurological diseases in elderly patients (A)</p> Signup and view all the answers

    What is the potential mortality rate in critically ill patients due to diagnosis complications?

    <p>Up to 50% (C)</p> Signup and view all the answers

    Which of the following is considered a common finding on ultrasound for diagnosing acute cholecystitis?

    <p>Pericholecystic fluid (D)</p> Signup and view all the answers

    What are the newly expanded indications for percutaneous transhepatic gallbladder drainage (PTGBD)?

    <p>Cholangitis and biliary obstruction (C)</p> Signup and view all the answers

    Which procedure was first performed much later than the initial cholecystostomy?

    <p>Image-guided cholecystostomy (D)</p> Signup and view all the answers

    What is a critical characteristic of EUS-GBD as a medical procedure?

    <p>It is relatively new and technically challenging. (C)</p> Signup and view all the answers

    What is the primary reason for keeping patients fasting overnight before a procedure involving the common bile duct?

    <p>To ensure adequate distension of the gallbladder (B)</p> Signup and view all the answers

    Which imaging technique can confirm the patency of the cystic duct?

    <p>Percutaneous cholecystogram (A)</p> Signup and view all the answers

    What is a significant technical limitation in performing PC procedures?

    <p>Narrow or tortuous cystic duct (D)</p> Signup and view all the answers

    Under what circumstances might the trans-peritoneal route be preferred over the transhepatic route for PC?

    <p>Coagulopathy or diffuse liver diseases (A)</p> Signup and view all the answers

    What is a relative contraindication for percutaneous cholecystostomy procedures?

    <p>Coagulopathy (B)</p> Signup and view all the answers

    What is a potential consequence of a significant pneumothorax following a trans-hepatic procedure?

    <p>Immediate chest tube placement (A)</p> Signup and view all the answers

    What complication can arise from a significant bile leak after a procedure?

    <p>Biliary pleural fistula (D)</p> Signup and view all the answers

    In the context of managing abdominal complications, what rare event may occur due to inadvertent perforation?

    <p>Fulminant peritonitis (B)</p> Signup and view all the answers

    What percentage of mortality is reported in patients due to biliary complications following procedures?

    <p>3.6% (D)</p> Signup and view all the answers

    What early complication is associated with the immediate post-procedural period following a trans-hepatic route?

    <p>Pericatheter skin excoriation (A)</p> Signup and view all the answers

    Flashcards

    Acute Cholecystitis

    Inflammation of the gallbladder (GB), often caused by gallstones or critical illness.

    Percutaneous Cholecystostomy (PC)

    Image-guided drainage of the gallbladder, often used when surgery is not feasible for severe acute cholecystitis.

    Gallstones

    Solid material that forms in the gallbladder and can lead to cholecystitis.

    Acalculous Cholecystitis

    Inflammation of the gallbladder WITHOUT gallstones, often linked to critical illness or prolonged ICU stays.

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    Cholecystectomy

    Surgical removal of the gallbladder.

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    Cholecystocutaneous fistula

    An abnormal connection between the gallbladder and the skin, often caused by a complication of percutaneous cholecystectomy (PC).

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    Cholangitic abscess

    A collection of pus in the bile ducts, often a complication of acute cholecystitis.

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    Biliary peritonitis

    Inflammation of the peritoneum (lining of the abdominal cavity) caused by a leak of bile.

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    Tractogram

    An imaging study that maps the path of the bile ducts to identify any leaks or blockages.

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    How does a cholecystocutaneous fistula affect PC?

    It can lead to persistent biliary leakage after the PC catheter is removed because the fistula provides a direct pathway for bile to leak out.

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    Laparoscopic Cholecystectomy

    A minimally invasive surgical procedure that involves removing the gallbladder through small incisions using a laparoscope (a viewing instrument with a camera).

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    What is the Swiss Association of Laparoscopic and Thoracoscopic Surgery database?

    A large database that tracks outcomes of laparoscopic and thoracoscopic surgeries, including cholecystectomy. This database is used to study risk factors and complications associated with these procedures.

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    Why is Percutaneous Cholecystostomy (PC) preferred over surgery in some cases?

    PC is preferred in cases where surgery is too risky or impossible due to patient's condition, such as severe acute cholecystitis with complications.

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    Evidence-based current clinical practice:

    Percutaneous cholecystostomy (PC) is now widely accepted as a safe and effective treatment option for complicated acute cholecystitis.

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    Causes of Acute Cholecystitis

    Acute cholecystitis (inflammation of the gallbladder) can be triggered by factors like gallstones, critical illness, prolonged mechanical ventilation, dehydration, sepsis, and increased inflammatory cytokines.

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    Why is Diagnosing Acute Cholecystitis Difficult?

    Diagnosing acute cholecystitis can be challenging, especially in critically ill patients, as symptoms can be masked or mimicked by their underlying condition. This makes it difficult to differentiate cholecystitis from other medical problems.

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    What is a Percutaneous Transhepatic Gallbladder Drainage (PTGBD)?

    PTGBD is a procedure that involves inserting a drainage tube directly into the gallbladder through the liver, guided by ultrasound. It's used to drain bile and relieve pressure in the gallbladder, mainly when surgery is too risky.

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    When is PTGBD Used?

    PTGBD is used in cases of complicated acute cholecystitis, especially in patients with severe illness, where surgery is not feasible. It can also be used for other gallbladder issues, such as cholangitis and obstruction.

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    EUS-GBD for Cholecystitis?

    Endoscopic ultrasound-guided transmural gallbladder drainage (EUS-GBD) is a relatively new, technically challenging procedure used to drain the gallbladder. It's performed by skilled endoscopists and is gaining popularity for its minimally invasive nature.

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    PC for non-responders

    Percutaneous Cholecystostomy (PC) can be done if a patient with acute cholecystitis doesn't improve with antibiotics, pain meds, and anti-inflammatories after 3 days.

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    PC for the elderly

    PC is a good option for elderly patients with acute cholecystitis, especially if they have other health problems like heart or brain issues.

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    Why PC in the ICU?

    PC can be used to treat acute cholecystitis in the ICU because it's a less risky procedure than surgery in critically ill patients.

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    Trauma and Cholecystitis

    People with severe injuries (trauma) are more likely to get acute cholecystitis, so PC might be used right away.

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    Burns and Cholecystitis

    Severe burns can also cause cholecystitis, especially if the patient needs long-term intravenous feeding and is dehydrated.

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    Patent Cystic Duct

    A cystic duct that is open and allows bile to flow freely from the gallbladder to the common bile duct.

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    Percutaneous Cholecystogram

    An imaging test used to visualize the gallbladder and cystic duct by injecting contrast dye directly into the gallbladder.

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    Transhepatic Route

    A route for accessing the gallbladder through a puncture made directly through the liver.

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    Transperitoneal Route

    A route for accessing the gallbladder through a puncture made through the abdominal wall.

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    Why is the transhepatic route often preferred?

    The transhepatic route is often preferred for percutaneous cholecystostomy due to its better anchoring of the catheter, reduced risk of bile leakage, and faster tract maturation due to fibrin deposition in the liver.

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    Bilio-pleural fistula

    An abnormal connection between the bile ducts and the lung lining, typically a complication of percutaneous cholecystectomy (PC).

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    Bilio-pneumothorax

    A condition characterized by air and bile in the space between the lung and chest wall.

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    Empyema

    A build-up of pus in the space between the lung and chest wall.

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    Bowel perforation

    A hole in the intestine, a rare complication of PC caused by a needle piercing the bowel wall.

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    Study Notes

    Acute Cholecystitis and Percutaneous Cholecystostomy

    • Acute cholecystitis (AC) is gallbladder inflammation, ranging from mild to severe.
    • Gallstones and critical illnesses are common causes.
    • Mild AC is treated medically, while moderate/severe AC often requires early cholecystectomy.
    • Cholecystectomy isn't always feasible due to comorbidities.
    • Percutaneous cholecystostomy (PC) is a minimally invasive procedure to drain the gallbladder.

    Indications for PC

    • Patients at high risk for surgery due to comorbidities (e.g., severe AC, calculous or acalculous, emphysematous, hemorrhagic, pregnancy).
    • Not responding to conservative treatment (IV antibiotics, analgesics, anti-inflammatory meds) after 3 days.
    • Severe AC in the elderly or patients with cardiovascular/neurological conditions.
    • Acalculous AC in ICU patients, polytrauma patients, or burn patients.
    • Emphysematous cholecystitis (gas-producing organisms) – a risky condition, but PC is an alternative to cholecystectomy.
    • AC in pregnancy- PC may be performed when conservative treatment isn't enough, followed by cholecystectomy post-partum
    • Hemorrhagic cholecystitis - a complication where blood vessels in the gallbladder are damaged, and surgery may not be feasible.
    • Gallbladder perforation—PC is life-saving in these cases.
    • Iatrogenic gallbladder perforation (after liver biopsy) can be effectively treated with PC.
    • Biliary decompression in patients with cholangitis or pancreatitis who can't undergo ERCP or PTBD.
    • Cholangitis, biliary obstruction, or as a potential route for stone extraction or dissolution

    Contraindications

    • No absolute contraindications are documented to date.
    • Relative contraindications include coagulopathy (low platelet count or high INR), ascites.
    • Patients with a severely contracted gallbladder with multiple stones may have placement difficulty.

    Technique

    • Complete blood count (including platelets), coagulation studies (INR and PT), and liver function tests are standard pre-procedure.
    • Antibiotics are administered to cover potential bacterial infections.
    • Imaging guidance (ultrasound or CT) is used to plan the approach (transhepatic or trans-peritoneal).
    • A small puncture is made, and a guidewire is inserted into the gallbladder.
    • Dilatation of the tract is performed until a catheter can be placed.
    • Contrast cholecystogram is sometimes performed to ensure catheter placement.
    • Local anesthesia and analgesia are typically used during the procedure.
    • Intercostal approach is often preferred to the trans-peritoneal route for the transhepatic approach.

    Post-procedure Care

    • Patient vitals monitored for several hours following the procedure.
    • Adequate hydration and antibiotics are continued.
    • Regular dressing and catheter care are essential.

    Complications

    • Minor complications include pain, catheter dislodgement, mild hemobilia.
    • Moderate complications include severe hemorrhage, biliary leakage, pleural/pulmonary issues, bowel perforation, and vasovagal syncope.
    • Delayed complications can include cystic duct/common bile duct stones, subhepatic, gallbladder bed, and subphrenic abscesses, or cholecystocutaneous/cholecystohepatic fistula.
    • Recurrence of cholecystitis can occur after 7- 1085 days.

    Newer Alternatives

    • Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is being increasingly used, offering advantages.
    • Lumen-apposing metallic stents (LAMS) or internalization of PC (using cholecystoenterostomy stent, EUS guided) could be alternatives.

    Outcomes

    • Generally, PC is a safe and effective procedure with relatively high success and favorable outcomes.
    • However, recurrence of AC and biliary issues are possible, especially if cholecystectomy isn't performed in all high-risk patients.

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    Description

    This quiz covers the essentials of acute cholecystitis (AC) and the role of percutaneous cholecystostomy (PC) in its management. Learn about the indications for PC, patient risk factors, and treatment alternatives in cases of severe AC. Ideal for medical students and healthcare professionals seeking insights into gallbladder diseases.

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