Acid-Base Imbalances Quiz
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Questions and Answers

A patient presents with the following ABG results:

  • pH: 7.29
  • PaCO2: 52 mmHg
  • HCO3-: 25 mEq/L What is the acid-base disturbance?

  • Respiratory acidosis (correct)
  • Respiratory alkalosis
  • Metabolic acidosis
  • Metabolic alkalosis

A patient with diabetic ketoacidosis (DKA) has the following ABG results:

  • pH: 7.22
  • PaCO2: 28 mmHg
  • HCO3-: 12 mEq/L What is the primary acid-base disturbance?

  • Metabolic alkalosis
  • Respiratory acidosis
  • Metabolic acidosis (correct)
  • Respiratory alkalosis

A patient with prolonged vomiting has the following ABG results:

  • pH: 7.50
  • PaCO2: 47 mmHg
  • HCO3-: 34 mEq/L What is the acid-base disturbance?

  • Respiratory acidosis with compensation
  • Metabolic acidosis
  • Metabolic alkalosis with compensation (correct)
  • Respiratory alkalosis

A patient with a history of COPD presents with the following ABG results:

  • pH: 7.37
  • PaCO2: 55 mmHg
  • HCO3-: 30 mEq/L What is the acid-base status?

<p>Fully compensated respiratory acidosis (C)</p> Signup and view all the answers

A patient experiencing sepsis has the following ABG results:

  • pH: 7.31
  • PaCO2: 32 mmHg
  • HCO3-: 16 mEq/L What is the acid-base disturbance?

<p>Metabolic acidosis with compensation (D)</p> Signup and view all the answers

A post-operative patient is hypoventilating and presents with the following ABG results:

  • pH: 7.20
  • PaCO2: 60 mmHg
  • HCO3:: 24 mEq/L What is the acid-base disturbance?

<p>Respiratory acidosis (B)</p> Signup and view all the answers

A patient has the following ABG results:

  • pH: 7.45
  • PaCO2: 30 mmHg
  • HCO3-: 20 mEq/L What is the acid-base status?

<p>Fully compensated respiratory alkalosis (C)</p> Signup and view all the answers

A patient presents with the following ABG results:

  • pH: 7.10
  • PaCO2: 60 mmHg
  • HCO3-: 18 mEq/L What is the acid-base disturbance?

<p>Mixed acidosis (C)</p> Signup and view all the answers

Flashcards

Respiratory Acidosis

A state where the blood pH is below 7.35 due to an excess of CO2 in the blood, often caused by hypoventilation.

Metabolic Acidosis

A state where the blood pH is below 7.35 due to an increase in acid production or a loss of bicarbonate, often seen in diabetic ketoacidosis, kidney failure, or severe diarrhea.

Respiratory Alkalosis

A state where the blood pH is above 7.45 due to a decrease in CO2 levels in the blood, often caused by hyperventilation.

Metabolic Alkalosis

A state where the blood pH is above 7.45 due to an excess of bicarbonate or a loss of acid, often caused by prolonged vomiting or excessive use of antacids.

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Compensation

A state where the body compensates for an initial acid-base disturbance by adjusting the other system to maintain a normal pH.

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Fully Compensated Acid-Base Disturbance

A state where the body successfully compensates for the initial acid-base disturbance, resulting in a normal pH.

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Uncompensated Acid-Base Disturbance

A state where the body is unable to fully compensate for the initial acid-base disturbance, resulting in an abnormal pH.

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Mixed Acid-Base Disturbance

A state where both respiratory and metabolic systems contribute to an abnormal pH.

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PaCO2 (Partial Pressure of Carbon Dioxide)

The partial pressure of carbon dioxide (CO2) in arterial blood, reflecting the body's ability to eliminate CO2 through respiration.

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HCO3- (Bicarbonate)

The concentration of bicarbonate (HCO3-) in arterial blood, representing the body's ability to buffer acids.

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pH (Potential of Hydrogen)

The measure of the acidity or alkalinity of the blood, with a normal range of 7.35 to 7.45.

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Diabetic Ketoacidosis (DKA)

A common complication of diabetes mellitus characterized by high blood glucose, ketones, and metabolic acidosis.

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Chronic Obstructive Pulmonary Disease (COPD)

A condition characterized by shortness of breath, mucus production, and chronic airway obstruction, often leading to respiratory acidosis.

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Sepsis

A condition characterized by the presence of harmful microorganisms in the bloodstream, often leading to metabolic acidosis.

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Hypoventilation

The process of artificially assisting a patient's ventilation, often necessary after surgery or in cases of respiratory failure.

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Hyperventilation

The process of breathing too rapidly or deeply, often caused by anxiety, pain, or metabolic acidosis.

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Prolonged Vomiting

A condition characterized by excessive vomiting, leading to a loss of stomach acid and metabolic alkalosis.

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Hypoventilation

A medical condition that causes a buildup of CO2 in the blood, leading to a drop in blood pH.

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Dyspnea

Abnormal shortness of breath, often due to a lung condition or other medical problem.

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Hyperpnea

An increased rate and depth of breathing, often a response to metabolic acidosis or other medical conditions.

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Acidosis

A condition characterized by a high level of acid (hydrogen ions) in the blood, leading to a drop in blood pH.

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Alkalosis

A condition characterized by a high level of alkaline (bicarbonate ions) in the blood, leading to an increase in blood pH.

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Buffer

A substance that helps maintain a stable pH by absorbing or releasing hydrogen ions.

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Bicarbonate (HCO3-)

A substance that helps maintain a stable pH by absorbing or releasing hydrogen ions. In the context of acid-base balance, bicarbonate is a key buffer.

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Carbon Dioxide (CO2) Elimination

The process of breathing out CO2, which is essential for maintaining acid-base balance.

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Hypoventilation

A condition where the body fails to eliminate CO2 effectively, leading to respiratory acidosis.

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Hyperventilation

A condition where the body eliminates CO2 too rapidly, often leading to respiratory alkalosis.

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Acid Production or Retention

A condition where the body produces or retains too much acid, contributing to metabolic acidosis.

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Bicarbonate Loss

A condition where the body loses too much bicarbonate, often due to diarrhea or kidney failure, contributing to metabolic acidosis.

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Bicarbonate Retention

A condition where the body retains too much bicarbonate, often due to prolonged vomiting or excessive use of antacids, contributing to metabolic alkalosis.

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Acid Loss

A condition where the body loses too much acid, often due to prolonged vomiting, contributing to metabolic alkalosis.

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Acid Retention

A condition where the body retains too much acid, often due to kidney failure or diabetes, contributing to metabolic acidosis.

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Study Notes

Acid-Base Imbalances

  • Definition: Acid-base imbalances are disturbances in the body's pH balance, impacting various physiological processes.
  • Assessment: Blood gas analysis (ABG) measurements, including pH, PaCO2, and HCO3-, are crucial for diagnosing acid-base imbalances.

Respiratory Acidosis

  • Cause: Hypoventilation, impairing CO2 elimination.
  • pH: Low (acidic)
  • PaCO2: Elevated
  • HCO3-: May be normal (uncompensated) or slightly elevated (compensated)
  • Compensation: Kidneys attempt to retain bicarbonate to compensate for the decreased pH.

Metabolic Acidosis

  • Cause: Excess acid production, loss of bicarbonate
  • pH: Low (acidic)
  • PaCO2: Often decreased (compensatory hyperventilation)
  • HCO3-: Low
  • Compensation: Lungs attempt to decrease CO2 by increasing the RR (rate and depth) to restore pH within the normal range.

Respiratory Alkalosis

  • Cause: Hyperventilation, leading to excessive CO2 loss.
  • pH: High (alkaline)
  • PaCO2: Low
  • HCO3-: May be normal (uncompensated) or slightly decreased (compensated).
  • Compensation: Kidneys attempt to excrete bicarbonate to counteract the alkaline pH.

Metabolic Alkalosis

  • Cause: Loss of acid, or excess bicarbonate intake
  • pH: High (alkaline)
  • PaCO2: Often increased (compensatory hypoventilation).
  • HCO3-: Elevated.
  • Compensation: Lungs attempt to increase CO2 to bring CO2 back to normal levels.

Diabetic Ketoacidosis (DKA)

  • Type of Acid-base Imbalance: Metabolic acidosis.
  • Cause: Insufficient insulin causes the body to break down fats for energy, producing ketones that lower blood pH. Fat metabolism produces acidic ketones.

Determining the Acid-Base Imbalance

  • A patient's symptoms and clinical presentation must be considered in conjunction with the ABG results to confirm and justify the cause for a particular acid-base imbalance.

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Description

This quiz covers the concepts of acid-base imbalances, highlighting their definitions, causes, and assessment techniques. It focuses on understanding respiratory acidosis, metabolic acidosis, and respiratory alkalosis, including the body's compensatory mechanisms. Test your knowledge on blood gas analysis and its significance in diagnosing these imbalances.

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