Acid-Base Chemistry Quiz
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Questions and Answers

A solution contains 1 gEq of solute per liter of solution. Which of the following terms best describes this type of solution?

  • Molar
  • Normal (correct)
  • Molal
  • Weight/volume
  • You have 100 ml of a 5% solution. What is the final concentration if you add 50 ml of water?

  • 6.67%
  • 2.5%
  • 3.33% (correct)
  • 10%
  • What is the defining characteristic of an acid, according to the Brönsted-Lowry definition?

  • Absorbs H+ ions
  • Accepts a proton
  • Is a proton donor (correct)
  • Produces OH- ions
  • Which of the following is NOT a characteristic of a base substance?

    <p>Contains sodium ions (D)</p> Signup and view all the answers

    Which of the following is an example of a nonhydroxide base?

    <p>Ammonia (B)</p> Signup and view all the answers

    Which of the following is most likely to serve as a nonhydroxide base?

    <p>Protein (B)</p> Signup and view all the answers

    Where does ammonia play its most significant role as a base buffer?

    <p>Kidney (D)</p> Signup and view all the answers

    What is an accurate statement about blood proteins?

    <p>Blood proteins are crucial for maintaining blood pH (A)</p> Signup and view all the answers

    What is the relationship between pH and hydrogen ion concentration ([H+])?

    <p>A decrease in pH indicates an increase in [H+] (A), A change of 1 pH unit represents a 10-fold change in [H+] (B)</p> Signup and view all the answers

    If a patient's blood pH drops from 7.40 to 7.20, what is the approximate change in hydrogen ion ([H+]) concentration?

    <p>Ten-fold increase (B)</p> Signup and view all the answers

    Which of these is considered a neutral solution in the human body?

    <p>pH 7.0 (B)</p> Signup and view all the answers

    Which of the following individuals would be expected to have the highest percentage of body water?

    <p>A 1-year-old child (B)</p> Signup and view all the answers

    Which of these does NOT contribute to the variation in individual's total body water?

    <p>Blood type (B)</p> Signup and view all the answers

    What is the approximate ratio of intracellular water to extracellular water in the body?

    <p>2:1 (C)</p> Signup and view all the answers

    Which of these statements regarding water in the body is FALSE?

    <p>Water content is highest in the aged. (D)</p> Signup and view all the answers

    Which of the following would be considered a compartment within the extracellular fluid?

    <p>Blood plasma (B)</p> Signup and view all the answers

    Given the following ABG results: pH = 7.25, PCO2 = 50 mm Hg, HCO3– = 22 mEq/L. What is the most likely acid-base diagnosis?

    <p>Acute (uncompensated) respiratory acidosis (A)</p> Signup and view all the answers

    Given the following ABG results: pH = 7.58, PCO2 = 32 mm Hg, HCO3– = 30 mEq/L. What is the most likely acid-base diagnosis?

    <p>Acute (uncompensated) metabolic alkalosis (B)</p> Signup and view all the answers

    Given the following ABG results: pH = 7.38, PCO2 = 28 mm Hg, HCO3– = 18 mEq/L. What indicates the most likely acid-base diagnosis?

    <p>Partially compensated metabolic acidosis (C)</p> Signup and view all the answers

    What would most likely cause an uncompensated metabolic alkalosis?

    <p>Excessive vomiting (A)</p> Signup and view all the answers

    What is the main mechanism of compensation in respiratory acidosis?

    <p>Increased renal reabsorption of bicarbonate (D)</p> Signup and view all the answers

    A patient presents with a pH of 7.5, PCO2 of 30mmHg and a HCO3- of 25mEq/L. What is the most appropriate interpretation of these ABG results?

    <p>Uncompensated respiratory alkalosis (D)</p> Signup and view all the answers

    A patient has a pH of 7.35, PCO2 of 45mmHg, and HCO3- of 28mEq/L. Which of the following is the most likely acid-base diagnosis?

    <p>Respiratory Acidosis (D)</p> Signup and view all the answers

    A patient is experiencing hyperventilation. What acid-base disturbance would you anticipate?

    <p>Respiratory alkalosis (D)</p> Signup and view all the answers

    What happens to the solubility of gases in a liquid if the pressure is increased?

    <p>It increases. (B)</p> Signup and view all the answers

    What is the primary goal of acid-base homeostasis?

    <p>Maintaining a normal pH level. (C)</p> Signup and view all the answers

    Which of the four pressures is NOT a driving force for fluid filtration across the capillary wall?

    <p>Hydrostatic pressure within the tissue space. (C)</p> Signup and view all the answers

    Which of the following factors can affect how much of a substance will go into solution?

    <p>All of the above. (D)</p> Signup and view all the answers

    What is the relationship between temperature and the solubility of most solids?

    <p>Solubility increases as temperature increases. (B)</p> Signup and view all the answers

    What is the most common cause of acute hyponatremia?

    <p>Postoperative iatrogenic causes. (C)</p> Signup and view all the answers

    What is the relationship between pressure and the solubility of most liquids?

    <p>Solubility remains constant with increasing pressure. (D)</p> Signup and view all the answers

    What is the relationship between temperature and the solubility of gases?

    <p>Solubility decreases with increasing temperature. (B)</p> Signup and view all the answers

    What physiological process directly causes respiratory alkalosis?

    <p>Decreased arterial PCO2 (A)</p> Signup and view all the answers

    Which of the following is the most common cause of respiratory alkalosis in patients with pulmonary disease?

    <p>Hypoxemia (D)</p> Signup and view all the answers

    Which of the following is NOT a potential cause of respiratory alkalosis?

    <p>Central nervous system depression (C)</p> Signup and view all the answers

    What is the most likely cause of iatrogenic respiratory alkalosis?

    <p>Mechanical hyperventilation (A)</p> Signup and view all the answers

    Which of the following are signs and symptoms of acute respiratory alkalosis? (Select all that apply)

    <p>Convulsions (A), Dizziness (C), Paresthesia (D)</p> Signup and view all the answers

    How do the kidneys compensate for respiratory alkalosis?

    <p>Renal excretion of HCO3- (C)</p> Signup and view all the answers

    Which of the following statements is TRUE about respiratory alkalosis?

    <p>It is characterized by an increase in blood pH. (B)</p> Signup and view all the answers

    Which of the following conditions is NOT a potential cause of hyperventilation, and therefore, respiratory alkalosis?

    <p>Central nervous system depression (B)</p> Signup and view all the answers

    What is the key difference between an open and a closed buffer system?

    <p>An open system features molecules that leave the system, while a closed system only contains molecules that remain within (B)</p> Signup and view all the answers

    What is a primary reason for the bicarbonate buffer system being considered a powerful buffer?

    <p>It has a higher capacity than any other buffer system due to its open nature. (D)</p> Signup and view all the answers

    Which of these situations would disrupt the efficiency of the carbonic acid/bicarbonate buffer system?

    <p>A failure of the lungs to eliminate CO2 at a sufficient rate to match the body's production. (D)</p> Signup and view all the answers

    Given the equation [H+] = (KA  [H2CO3])/[HCO3–], what factor(s) can be used to determine the hydrogen ion concentration ([H+])?

    <p>HCO3– and H2CO3 only (C)</p> Signup and view all the answers

    Why are phosphate buffer systems considered 'closed' systems?

    <p>All components of the acid-base reaction remain within the system, preventing their loss. (B)</p> Signup and view all the answers

    How does hyperventilation impact the closed buffer systems?

    <p>They release more H+ ions, resulting in a rise in pH. (B)</p> Signup and view all the answers

    Which of the following is NOT a reason why the bicarbonate buffer system is considered an open system?

    <p>Its chemical reactions are extremely rapid, making it an efficient buffer. (C)</p> Signup and view all the answers

    Which of the following options correctly describes the relationship between the pH and the concentration of hydrogen ions ([H+])?

    <p>As pH increases, the [H+] decreases. (C)</p> Signup and view all the answers

    Flashcards

    Molar Solution

    A solution with 1 mol of solute per liter of solution.

    Normal Solution

    A solution that contains 1 gEq of solute per liter.

    Dilution Calculation

    Adjusting concentration by adding solvent.

    Characteristic of an Acid

    An acid is a proton (H+) donor.

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    Definition of a Base

    A base is any compound that accepts a proton.

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    Nonhydroxide Bases

    Examples include ammonia and carbonates.

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    Ammonia's Role

    Ammonia is important in renal acid excretion.

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    Blood Proteins

    Proteins composed of amino acids, not fatty acids.

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    pH Definition

    pH is the negative logarithm of H+ ion concentration.

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    Neutral pH

    A solution with a pH of 7.0 is neutral, like pure water.

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    pH Change & H+ Concentration

    A change in pH of 0.3 units equals a two-fold change in H+ concentration.

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    Body Water Percentage

    Water constitutes 45% to 80% of an individual's body weight, depending on weight, sex, and age.

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    Intracellular Water

    Intracellular water accounts for approximately two-thirds of total body water.

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    Extracellular Water

    Extracellular water is the remaining one-third of total body water outside cells.

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    Age and Body Water

    Water content is highest in infants and decreases with age.

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    H+ Concentration Increase

    A drop in pH from 7.40 to 7.10 increases H+ concentration significantly.

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    Solubility and Temperature

    Most solids dissolve better in higher temperatures; gases do worse.

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    Pressure and Gases

    Gas solubility in liquids increases with higher pressure.

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    Concentration Effect

    The amount of solute or solvent affects how much dissolves.

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    Starling Forces

    Fluid movement across capillaries is affected by hydrostatic and oncotic pressures.

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    Colloid Osmotic Pressure (COP)

    Pressure created by proteins in a solution that pulls water into the vessel.

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    Acute Hyponatremia Causes

    Common causes include postoperative issues and water intoxication.

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    Acid-Base Homeostasis Goal

    To maintain normal pH in body fluids.

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    Hydrostatic Pressure

    The pressure exerted by fluids within vessels that drives filtration.

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    Open Buffer System

    A buffer system that can exchange components with the external environment.

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    Closed Buffer System

    A buffer system where all components remain within the system and do not exchange with the environment.

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    Bicarbonate Buffer Capacity

    Bicarbonate has the greatest buffering capacity among buffer systems due to its open nature.

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    Effect of Hyperventilation

    Hyperventilation causes closed buffer systems to release more H+ ions due to increased CO2 removal.

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    Factors Affecting [H+]

    [H+] can be determined by the ratio of H2CO3 to HCO3– and inorganic phosphorus levels.

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    Carbonic Acid Role

    Carbonic acid (H2CO3) is volatile and can easily convert to CO2 for removal from the body.

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    Lung Function in Buffers

    Lungs must effectively excrete CO2 to maintain acid-base balance in the bicarbonate system.

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    Nonvolatile Acids

    Acids that cannot be easily removed from the body and thus affect buffer efficiency if accumulated.

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    Respiratory alkalosis

    A condition resulting from lowered arterial PCO2, causing increased blood pH.

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    Common cause of respiratory alkalosis

    Hypoxemia, or low arterial PO2, often leads to hyperventilation.

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    Potential causes of respiratory alkalosis

    Includes anxiety, hypoxemia, central nervous system injuries, and pain.

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    Iatrogenic respiratory alkalosis

    Respiratory alkalosis caused by medical treatment, commonly during mechanical ventilation.

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    Signs of acute respiratory alkalosis

    Common symptoms include paresthesia, dizziness, and convulsions.

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    Compensation for respiratory alkalosis

    The kidneys compensate by excreting bicarbonate (HCO3–) in urine.

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    Effects of severe hyperventilation

    Can cause dizziness, hyperactive reflexes, and convulsions.

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    Role of the kidneys in respiratory alkalosis

    Kidneys excrete bicarbonate to lower blood pH and stabilize acid-base balance.

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    Normal Acid-Base Status

    pH, PCO2, and HCO3– within normal limits indicate normal acid-base status.

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    Uncompensated Metabolic Alkalosis

    High pH with elevated HCO3– and normal PCO2 indicates acute metabolic alkalosis.

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    Fully Compensated Respiratory Alkalosis

    Normal pH with low PCO2 and low HCO3– indicates fully compensated respiratory alkalosis.

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    Partially Compensated Metabolic Acidosis

    Acidosis with compensation shown by low HCO3–, low PCO2, and low pH.

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    Acidosis

    A condition where the blood pH is below 7.35, indicating increased H+ concentration.

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    Respiratory Acidosis

    Excess CO2 due to respiratory failure leading to a low pH.

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    Metabolic Acidosis

    Decreased HCO3– and low pH indicating an excess of acid or loss of base.

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    Compensatory Mechanisms

    Body's response to restore pH balance via respiratory or metabolic changes.

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    Study Notes

    Multiple Choice Questions

    • Question 1: A uniform distribution of large molecules attracting and holding water is called a colloid.
    • Question 2: Red blood cells suspended in plasma are an example of a suspension.
    • Question 3: A stable mixture of two or more substances in a single phase is a solution.
    • Question 4: The ease with which a gas dissolves in a solvent is at least partially determined by gas temperature.

    Solubility

    • Solubility is the ease with which a solute dissolves in a solvent.
    • Nature of solute, nature of solvent, temperature, pressure, and concentration influence solubility.
    • Solubility of most solids increases with temperature; however, the solubility of gases varies inversely with temperature.
    • Solubility of gases in liquids varies directly with pressure.

    Gas Transport

    • Gas transport in the body is affected by changes in ambient pressure.
    • The solubility of dissolved gas is related to its pressure and to the solubility coefficient.

    Solution Types

    • A saturated solution holds the maximum amount of solute in a given volume at a constant temperature.
    • A solution with the maximum amount of solute that can be dissolved is a saturated solution.

    Osmotic Pressure

    • Osmotic pressure is the force produced by solvent particles.
    • It moves solvent molecules through a membrane into a solution.
    • Osmotic pressure depends on the number of particles in the solution.

    Electrolyte Solutions

    • Positive ions are called cations and negative ions are called anions.
    • Substances that conduct electricity are called electrolytes.
    • Electrolytes that dissociate in solution are nonelectrolytes.
    • Isotonic solutions have similar tonicity (solute concentration).

    Gram-Equivalent Weight

    • Gram equivalent weight is calculated by dividing the gram formula weight by the number of replaceable hydrogen atoms in a formula.

    Serum Values

    • Serum Na+ values can be converted to mEq/L.
    • The serum sodium concentration, including milliequivalents per liter, is an important consideration.

    Solution Concentration

    • A ratio solution expresses solute to solvent as a proportion.
    • A weight-volume solution expresses weight of solute per volume of solution.
    • A normality solution expresses gram-equivalent weight of solute per liter of solution.
    • A molar solution expresses moles of solute per liter of solution.

    Solution Dilution

    • The new concentration of a solution can be calculated using the dilution equation.
    • If 50 mL of water is added to 150 mL of a 6% solution, the new will be 4.5%.

    pH

    • pH is the negative logarithm of the hydrogen ion concentration.
    • A pH of 7.0 is neutral, and solutions with a higher pH are basic while those with a lower pH are acidic.
    • A solution that resists large changes in pH upon addition of an acid or base is called a buffer solution.

    Acid-Base Balance

    • The primary goal of acid-base homeostasis is to maintain normal pH.
    • The normal arterial blood pH ranges from 7.35 to 7.45.
    • Important buffers in acid-base balance include bicarbonate, hemoglobin, and phosphates.

    Compensatory Mechanisms

    • Compensatory mechanisms help balance acids and bases to maintain a normal pH balance.
    • Compensatory mechanisms are dependent on many systems including the lungs, kidneys, and blood.

    Acid-Base Disturbances

    • Acid-base disturbances occur when there is an imbalance between acid and base in the body.
    • Acidemia is an acid-base imbalance indicating an increase in hydrogen ions or a decrease in bicarbonate.
    • Alkalemia is an acid-base imbalance indicating a decrease in hydrogen ions or an increase in bicarbonate.

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    Description

    Test your knowledge on acid-base chemistry concepts, including definitions, characteristics, and solutions. This quiz covers terms like Brönsted-Lowry acids and bases, solution concentrations, and the role of buffers in biological systems. Perfect for anyone studying chemistry or related fields.

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