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Questions and Answers
Which enzyme is responsible for synthesizing acetylcholine from choline and acetyl-CoA?
Which enzyme is responsible for synthesizing acetylcholine from choline and acetyl-CoA?
What is acetylcholine transported into synaptic vesicles via?
What is acetylcholine transported into synaptic vesicles via?
Which enzyme degrades acetylcholine in the synaptic cleft?
Which enzyme degrades acetylcholine in the synaptic cleft?
What is the fate of the acetate after acetylcholine is degraded?
What is the fate of the acetate after acetylcholine is degraded?
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Where does acetylcholine bind after being released into the synaptic cleft?
Where does acetylcholine bind after being released into the synaptic cleft?
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Which of the following molecules are recycled back into the presynaptic neuron?
Which of the following molecules are recycled back into the presynaptic neuron?
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Study Notes
Synthesis of Acetylcholine
- Acetylcholine is synthesized from choline and acetyl coenzyme A (acetyl-CoA) by the enzyme choline acetyltransferase (ChAT).
Release of Acetylcholine
- Acetylcholine is released from the presynaptic nerve terminal into the synaptic cleft.
- Acetylcholine is transported into synaptic vesicles via VACIT.
- Acetylcholine is released from vesicles into the synaptic cleft by nerve impulse.
Binding of Acetylcholine
- Acetylcholine binds to the acetylcholine receptors on the postsynaptic membrane.
- Acetylcholine binds to receptors on muscle fibers.
Degradation of Acetylcholine
- Acetylcholine is degraded by the enzyme acetylcholinesterase (AChE).
- The products of degradation are choline and acetate.
Recycling of Products
- Choline is recycled back into the presynaptic neuron for the synthesis of new acetylcholine.
- Acetate is recycled by the nerve terminal.
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Description
This diagram illustrates the steps involved in the synthesis and degradation of acetylcholine, a neurotransmitter. Learn about the enzymes and processes involved in this biological process.
