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Acetylcholine Pathway in Salivary Gland Cells

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UnquestionableKremlin
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18 Questions

What is the primary function of the intrinsic factor secreted by the stomach?

To facilitate the absorption of vitamin B-12 in the intestines

Which of the following is NOT a function of the stomach?

Secretion of digestive enzymes

Which region of the stomach contains the gastric pits and glands?

All regions of the stomach contain gastric pits and glands

What is the primary function of saliva secreted by the salivary glands?

Lubrication and moisturization of the oral cavity

Which of the following stimuli inhibits the salivary gland's secretion of saliva?

Sleep

How does the salivary nervous system stimulate salivary secretion?

Through the release of norepinephrine, which binds to beta-adrenergic receptors on salivary gland cells

What is the relationship between the concentrations of Na+ and Cl- in saliva compared to plasma?

Saliva has lower concentrations of Na+ and Cl- than plasma

What is the relationship between the concentration of K+ in saliva compared to plasma?

Saliva has higher K+ concentration than plasma

How does the HCO3- concentration in saliva compare to plasma at low flow rates?

Saliva has lower HCO3- concentration than plasma

How does the HCO3- concentration in saliva compare to plasma at high flow rates?

Saliva has higher HCO3- concentration than plasma

Which enzyme in saliva can hydrolyze triglycerides without the help of bile salts?

Lingual lipase

What is the primary regulation of the salivary glands?

Sympathetic nervous system

What is the primary role of the sympathetic nervous system in relation to the GI system?

Inhibits motor activities of the GI system

Which component in saliva plays a crucial role in regulating the pH of saliva?

Bicarbonate

What percentage of water is absorbed by the small intestine?

78%

What is one of the key functions of saliva in the oral cavity, besides digestion?

Maintaining pH in the oral cavity

How does the flow rate of saliva impact the concentration of potassium (K+)?

Increased flow rate decreases K+ concentration

What happens to the pH of saliva as the flow rate increases?

The pH becomes more basic

Explore the pathway where acetylcholine binds to M3 receptors in salivary gland cells, leading to the production of secondary messengers IP3 & Ca2+ and subsequent effects such as secretion of saliva, smooth muscle contraction, vasodilation, and gland growth. Learn about factors that inhibit this pathway like sleep, fatigue, dehydration, fear, and acetylcholine-blocking drugs.

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