ACE Inhibitors - Renal Insufficiency and Hyperkalemia
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Questions and Answers

Which adverse effect is common to both K+-sparing diuretics and Na+ channel inhibitors?

  • Hypernatremia
  • Hyperkalemia (correct)
  • Hypokalemia
  • Hyponatremia

Which of the following is an adverse effect associated with triamterene but not with amiloride?

  • Nausea, vomiting, diarrhea
  • Photosensitivity (correct)
  • Musculoskeletal effects
  • Headache

What is a renal consideration regarding the use of triamterene?

  • Increases renal function
  • Contraindicated in patients with severe renal impairment (correct)
  • Preferred in patients with renal failure
  • No renal considerations needed

Which drug is associated with an increased risk of folic acid deficiency?

<p>Triamterene (C)</p> Signup and view all the answers

What is a common CNS adverse effect of both K+-sparing diuretics and Na+ channel inhibitors?

<p>Headache (B)</p> Signup and view all the answers

Which condition is a therapeutic use for Dutasteride?

<p>Prostate cancer prevention (B)</p> Signup and view all the answers

What is a common adverse effect of Finasteride therapy?

<p>Decreased libido (A)</p> Signup and view all the answers

Which drug interaction is associated with K+-sparing diuretics?

<p>Lisinopril (B)</p> Signup and view all the answers

What is a contraindication for Finasteride use?

<p>Pregnancy (B)</p> Signup and view all the answers

Which adverse effect is commonly associated with DHT levels increase after discontinuation of therapy?

<p>Gynecomastia (B)</p> Signup and view all the answers

What is a potential cause of renal insufficiency in patients using K+-sparing diuretics?

<p>Hypotension (A)</p> Signup and view all the answers

Which condition may be precipitated by bilateral renal artery stenosis in patients using aldosterone antagonists?

<p>Renal failure (C)</p> Signup and view all the answers

What can hyperkalemia in patients using Na+ channel inhibitors be attributed to?

<p>Decreased serum aldosterone levels (D)</p> Signup and view all the answers

Which population is at an increased risk of angioedema when using ACE inhibitors?

<p>African-Americans (C)</p> Signup and view all the answers

What is the recommended monitoring parameter for patients initiating ACE inhibitor therapy?

<p>BUN, electrolytes, and serum creatinine (B)</p> Signup and view all the answers

What is the expected response in creatinine levels when initiating an ACE inhibitor?

<p>Mild increase (B)</p> Signup and view all the answers

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