ABX Pharmacotherapeutics
40 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What type of antibiotics inhibit cell wall formation in bacteria?

  • Antifolate drugs
  • Fluoroquinolones
  • Protein synthesis inhibitors
  • Cell wall inhibitors (correct)
  • Which of the following is a common bacterial infection that can be caused by Chlamydia Trachomatis?

  • Strep pharyngitis
  • Bacterial conjunctivitis
  • Otitis externa
  • Trachoma (correct)
  • What is the typical duration of bacterial conjunctivitis?

  • 5-7 days (correct)
  • 1-2 days
  • 1-2 weeks
  • More than 2 weeks
  • What is the primary cause of otitis externa?

    <p>Heat and retained moisture</p> Signup and view all the answers

    Which antibiotic is commonly used to treat trachoma?

    <p>All of the above</p> Signup and view all the answers

    What is the common presentation of bacterial conjunctivitis?

    <p>Conjunctival erythema, eyelid edema</p> Signup and view all the answers

    Which bacteria is commonly associated with otitis externa?

    <p>Pseudomonas aeruginosa</p> Signup and view all the answers

    What is the name of the bacterium that causes trachoma?

    <p>Chlamydia Trachomatis</p> Signup and view all the answers

    What is the primary etiologic agent of Rocky Mountain Spotted Fever?

    <p>Rickettsia rickettsii</p> Signup and view all the answers

    What is the first-line treatment for animal bites infected with Pseudomonas aeruginosa?

    <p>Amoxicillin/Clavulanate</p> Signup and view all the answers

    What is the primary treatment for Lyme disease?

    <p>Doxycycline</p> Signup and view all the answers

    What is the etiologic agent of Aeuginosa infections?

    <p>Pseudomonas aeruginosa</p> Signup and view all the answers

    What is the primary treatment for CAP PNA caused by Streptococcus pneumoniae?

    <p>Clarithromycin</p> Signup and view all the answers

    What is the primary etiologic agent of Diverticulitis?

    <p>All of the above</p> Signup and view all the answers

    What is the treatment of choice for MRSA infections?

    <p>Vancomycin</p> Signup and view all the answers

    What is the primary manifestation of Lyme disease in the early stages?

    <p>Non-specific symptoms like headache and muscle pain</p> Signup and view all the answers

    Which formulation is not used for mucocutaneous candidiasis?

    <p>Suspension</p> Signup and view all the answers

    Which azole derivative requires gastric acid for absorption?

    <p>Ketoconazole</p> Signup and view all the answers

    Which azole derivative achieves significant concentration in CSF?

    <p>Fluconazole</p> Signup and view all the answers

    What is the elimination route for voriconazole?

    <p>Renal elimination</p> Signup and view all the answers

    What is the half-life of ketoconazole?

    <p>8 hours</p> Signup and view all the answers

    Which azole derivative is used topically under the brand name Lotrimin?

    <p>Clotrimazole</p> Signup and view all the answers

    What is the route of administration for itraconazole?

    <p>PO only</p> Signup and view all the answers

    Which of the following is NOT an azole derivative?

    <p>Amphotericin B</p> Signup and view all the answers

    Which of the following antifungal medications is known to penetrate the CSF?

    <p>Fluconazole</p> Signup and view all the answers

    What is a potential consequence of chronic use of fluconazole in high doses?

    <p>Increased risk of birth defects</p> Signup and view all the answers

    Which antifungal medication is particularly useful in the treatment of onychomycosis?

    <p>Itraconazole</p> Signup and view all the answers

    What is a major limitation of ketoconazole compared to itraconazole and fluconazole?

    <p>Greater potential for drug interactions</p> Signup and view all the answers

    What is a common use for the topical formulation of ketoconazole?

    <p>Treatment of seborrheic dermatitis</p> Signup and view all the answers

    What is a characteristic of Caspofungin?

    <p>All of the above</p> Signup and view all the answers

    What is a potential consequence of systemic administration of antifungal medications?

    <p>All of the above</p> Signup and view all the answers

    Which antifungal medication is used to prevent cryptococcal meningitis in patients with AIDS?

    <p>Fluconazole</p> Signup and view all the answers

    What is the most likely diagnosis of a patient with ear canal edema, discomfort, and pain with palpation of tragus/pinna?

    <p>Pneumo</p> Signup and view all the answers

    Which of the following is NOT a treatment option for Strep Throat?

    <p>Mupirocin topical</p> Signup and view all the answers

    What is the primary bacterium responsible for causing Impetigo?

    <p>S. aureus</p> Signup and view all the answers

    What is the treatment of choice for a patient with a Peritonsillar abscess?

    <p>Surgical I&amp;D and antibiotics</p> Signup and view all the answers

    Which of the following is a complication of tonsillitis?

    <p>Peritonsillar abscess</p> Signup and view all the answers

    What is the most likely diagnosis of a patient with red popular lesions that evolve to pustules and honeycomb-like crusting affecting facial areas?

    <p>Impetigo</p> Signup and view all the answers

    Which of the following bacteria is responsible for causing Cellulitis?

    <p>All of the above</p> Signup and view all the answers

    What is the treatment of choice for a patient with Impetigo?

    <p>Mupirocin topical</p> Signup and view all the answers

    Study Notes

    Antibiotics

    • Cell wall inhibitors: PCN, cephalosporins, carbapenems
    • Protein synthesis inhibitors: AGs, tetracyclines, macrolides, linezolid, mupirocin
    • Antifolate drugs
    • Fluoroquinolones

    Common Bacterial Infections

    • Bacterial conjunctivitis
      • Inflammation of conjunctiva from infection
      • Self-limited, resolves in 5-7 days
      • Presentation: conjunctival erythema, eyelid edema, mucopurulent discharge and crusting
    • Trachoma
      • Highly contagious ocular infection caused by Chlamydia Trachomatis
      • Presentation: roughening of inner surface of eye, corneal breakdown, eye discharge, light sensitivity
      • Treatments: Azithromycin single dose, Sulfacetamide ophthalmic solution, Tetracycline ophthalmic solution/ointment
    • Otitis Externa
      • Results from combo of heat and retained moisture with desquamation and maceration of epithelium of canal
      • Etiology: P. aeruginosa, S. Pneumo
      • Presentation: ear discharge, pain with palpation of tragus/pinna, ear canal edema and discomfort
      • Treatment: Topical otic abx +/- topical steroids (e.g. Neomycin/polymyxin/hydrocortisone otic suspension, Ciprofloxacin/dexamethasone otic suspension)
    • Strep Throat
      • Pharyngeal infections caused by GAS aka S. pyrogenes
      • Presentation: sore throat, fever, chills, purulent tonsillar exudate, cervical LAD
      • Treatments: PCN V, 1G cephalosporin (cephalexin) if PCN allergy, Clindamycin if allergic to PCN and cephalosporins
    • Peritonsillar abscess
      • Aka quinsy, complication of tonsillitis
      • Consists of collection of pus in peritonsillar space; considered an ENT emergency
      • Etiology: Oral flora including anaerobes, GAS
      • Presentation: severe u/l sore throat, dysphagia, dysphonia, referred otalgia, "hot potato voice", LAD, trismus
      • Treatment: Surgical I&D and Abx (e.g. Clindamycin or metronidazole and benzathine PCN G)

    Skin Infections

    • Impetigo
      • Superficial skin infection seen in young children
      • Etiology: S. aureus, S. pyogenes
      • Presentation: red papular lesions that evolve to pustules, honeycomb-like crusting affecting facial areas
      • Treatment: Mupirocin topical, Dicloxacillin or cephalexin if extensive
    • Cellulitis
      • Bacterial infection of skin; bacteria enter through cuts, scratches, burns, incisions, catheters, etc
      • Etiology: MRSA, MSSA, P. multocida (cat/dog bites), Eikenella cordoned (human bites), P. Aeruginosa (penetrating injury)
      • Presentation: localized pain, erythema, swelling, heat
      • Treatment: Amoxicillin/Clavulante for animal bites, Dicloxacillin or Oxacillin for MSSA, Clindamycin, vancomycin, or linezolid for MRSA

    Tick-Borne Illnesses

    • Rocky Mountain Spotted Fever
      • Tick/mite-born illness
      • Transmitted by American dog ticks (Dermacentor Variabilis) and Rocky Mountain wood tick (D. andersoni)
      • Etiology: R. Rickettsii
      • Presentation: evolving macular rash; rarely CNS involvement, hypovolemia, HoTN, renal failure
      • Treatment: Doxycycline, Chloramphenicol if allergic (or pregnant?)
    • Lyme disease
      • Spirochetal infection transmitted by ticks (Ixodes scapularis)
      • Etiology: Borrelia burgdorferi
      • Presentation: ECM (Stage 1), non-specific sx like HA, MSK pain, near deficits (stage 2), arthritis (stage 3)
      • Treatment: Doxycycline, Amoxicillin, cefuroxime, or erythromycin are alternative agents

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Exam2studyguide.docx

    Description

    This quiz covers the pharmacological treatment of bacterial infections, including antibiotics and their mechanisms of action, as well as common bacterial infections.

    More Like This

    Pharmacotherapeutics Overview
    36 questions

    Pharmacotherapeutics Overview

    EffortlessGyrolite7402 avatar
    EffortlessGyrolite7402
    Pharmacotherapeutics of Nitroprusside
    16 questions
    Linezolid Pharmacotherapeutics Quiz
    7 questions

    Linezolid Pharmacotherapeutics Quiz

    WellReceivedSquirrel7948 avatar
    WellReceivedSquirrel7948
    Use Quizgecko on...
    Browser
    Browser