14 Questions
What is the absorption pathway for oral tablets?
GI mucosa, superior mesenteric vein, portal vein, liver, inferior vena cava, heart
How do substances administered sublingually or buccally get absorbed?
Mucous membranes in the sublingual or buccal areas, sublingual or buccal veins and capillaries, jugular vein, superior vena cava, heart
What is the role of the liver in the absorption pathway of oral tablets?
Significant processing and metabolism
Which vein transports substances administered sublingually or buccally to the heart?
Jugular vein
What is the primary reason for using sublingual or buccal administration for certain medications?
To achieve rapid and efficient absorption without passing through the digestive tract
What is the main difference between sublingual and buccal administration?
Sublingual administration provides rapid onset, while buccal administration offers gradual absorption
What type of drugs can be absorbed through passive diffusion in sublingual and buccal administration?
Only unionized drugs
What role does the pH of saliva play in drug absorption in the sublingual and buccal route?
It influences the ionization of weak acid or weak base drugs, affecting their absorption
What is the purpose of using a small dose for sublingual tablet formulations?
To exert therapeutic effect in the limited surface area of the mouth
What is a common problem associated with nitroglycerin tablets?
Loss of content uniformity and potency due to factors like evaporation and capillary condensation
Why do buccal tablets typically not contain disintegrants?
To ensure gradual dissolution and absorption in the mouth
What is the purpose of mucoadhesive in buccal tablets?
To keep the tablet at the administration site
What is the primary function of chewable tablets?
To be chewed and swallowed for drug administration
What is the purpose of using layers in tablet formulation?
To separate incompatible ingredients and enable immediate or sustained drug release
Test your knowledge of the absorption pathway for buccal and sublingual oral tablets with this quiz. Explore how these tablets travel through the gastrointestinal (GI) tract and enter the bloodstream via the superior mesenteric vein and portal vein.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
