Absorption Pathway Quiz
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Questions and Answers

What is the absorption pathway for oral tablets?

  • Superior mesenteric vein, jugular vein, inferior vena cava, arterial circulation
  • Mucous membranes, jugular vein, superior vena cava, heart
  • Liver, arterial circulation, entire body
  • GI mucosa, superior mesenteric vein, portal vein, liver, inferior vena cava, heart (correct)

How do substances administered sublingually or buccally get absorbed?

  • Liver, inferior vena cava, arterial circulation
  • Mucous membranes in the sublingual or buccal areas, sublingual or buccal veins and capillaries, jugular vein, superior vena cava, heart (correct)
  • GI mucosa, superior mesenteric vein, portal vein, liver
  • Jugular vein, inferior vena cava, arterial circulation, entire body

What is the role of the liver in the absorption pathway of oral tablets?

  • Bypassing the digestive system
  • Absorption through mucous membranes
  • Direct transportation to the heart
  • Significant processing and metabolism (correct)

Which vein transports substances administered sublingually or buccally to the heart?

<p>Jugular vein (B)</p> Signup and view all the answers

What is the primary reason for using sublingual or buccal administration for certain medications?

<p>To achieve rapid and efficient absorption without passing through the digestive tract (A)</p> Signup and view all the answers

What is the main difference between sublingual and buccal administration?

<p>Sublingual administration provides rapid onset, while buccal administration offers gradual absorption (D)</p> Signup and view all the answers

What type of drugs can be absorbed through passive diffusion in sublingual and buccal administration?

<p>Only unionized drugs (D)</p> Signup and view all the answers

What role does the pH of saliva play in drug absorption in the sublingual and buccal route?

<p>It influences the ionization of weak acid or weak base drugs, affecting their absorption (C)</p> Signup and view all the answers

What is the purpose of using a small dose for sublingual tablet formulations?

<p>To exert therapeutic effect in the limited surface area of the mouth (B)</p> Signup and view all the answers

What is a common problem associated with nitroglycerin tablets?

<p>Loss of content uniformity and potency due to factors like evaporation and capillary condensation (A)</p> Signup and view all the answers

Why do buccal tablets typically not contain disintegrants?

<p>To ensure gradual dissolution and absorption in the mouth (D)</p> Signup and view all the answers

What is the purpose of mucoadhesive in buccal tablets?

<p>To keep the tablet at the administration site (C)</p> Signup and view all the answers

What is the primary function of chewable tablets?

<p>To be chewed and swallowed for drug administration (A)</p> Signup and view all the answers

What is the purpose of using layers in tablet formulation?

<p>To separate incompatible ingredients and enable immediate or sustained drug release (D)</p> Signup and view all the answers

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