ABO Blood Group System

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10 Questions

Which blood group has no antigens, but both anti-A and anti-B antibodies in the plasma?

O

What is the most common blood group?

O

What is the role of the Rh antigen in blood grouping?

Determines whether the blood group is positive or negative

Why is blood group O Rh negative blood (O-) often used in medical emergencies?

Because it has no A or B antigens

What is the importance of blood group testing in pregnant women?

To identify potential complications due to Rh incompatibility

What happens when red blood cells are mixed with anti-B antibodies in a blood group test?

The cells will clump together if the blood group is B

Why should Rh-negative women of child-bearing age only receive Rh-negative blood?

To prevent complications due to Rh incompatibility

What is the significance of blood group AB?

It has A and B antigens, but no antibodies

What is the purpose of blood group testing?

To ensure safe blood transfusions

What happens if the mother is Rh negative and the child is Rh positive?

It may cause complications if left untreated

Study Notes

The ABO System

  • There are 4 main blood groups defined by the ABO system: A, B, O, and AB
  • Blood group A has A antigens on red blood cells and anti-B antibodies in the plasma
  • Blood group B has B antigens on red blood cells and anti-A antibodies in the plasma
  • Blood group O has no antigens on red blood cells, but has both anti-A and anti-B antibodies in the plasma
  • Blood group AB has both A and B antigens on red blood cells, but no antibodies in the plasma

Blood Group O

  • Blood group O is the most common blood group
  • Group O red blood cells do not have any A or B antigens, making it safe to give to any other group

The Rh System

  • Red blood cells may have the Rh antigen, a protein that determines Rh positive or negative blood types
  • The presence or absence of the Rh antigen adds another layer of classification, making a total of 8 possible blood groups
  • O Rh negative blood (O-) can safely be given to anyone in most cases, as it does not have any A, B, or Rh antigens on the surface of the cells
  • O Rh negative blood is often used in medical emergencies when the blood type is not immediately known

Blood Group Test

  • A blood group test involves mixing red blood cells with different antibody solutions to determine blood type
  • The test detects whether red blood cells clump together in response to anti-A or anti-B antibodies, or whether they do not react to any antibodies, indicating blood group O

Importance of Blood Group Testing

  • Blood group testing is crucial for safe blood transfusions
  • Pregnant women are always given a blood group test to detect potential complications from Rh incompatibility between the mother and child
  • Rh-negative women of child-bearing age should only receive Rh-negative blood to avoid complications

Learn about the ABO blood group system, including the characteristics of blood groups A, B, AB, and O, and their respective antigens and antibodies.

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