Abnormal Neutrophil Function Quiz

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Which cells in the immune system are responsible for phagocytosis of invaders?

Basophils

Neutrophils (correct)

Lymphocytes

Eosinophils

Which cells present immunogens to T helper cells, the first step in an immune response?

Monocytes

Macrophages (correct)

Eosinophils

Basophils

Which type of cells have major histocompatibility complex (MHC) class II on their surface?

Monocytes (correct)

Basophils

Neutrophils

Eosinophils

Which cells mediate IgE allergic responses in the immune system?

Basophils Signup and view all the answers

What is the main function of neutrophils in the immune system?

Phagocytosis and inflammatory response Signup and view all the answers

Which cells have receptors for IgE and granules responsible for allergic reactions?

Eosinophils Signup and view all the answers

What is the main characteristic of Chédiak-Higashi Syndrome?

Defective locomotion Signup and view all the answers

Which disorder is characterized by a qualitative disorder of neutrophils with giant granules?

Chronic Granulomatous Disease Signup and view all the answers

What is the main effect of Myeloperoxidase Deficiency on bacterial and fungal killing by phagocytes?

Mild defect in bacterial killing, marked defect in fungal killing Signup and view all the answers

Which disorder is caused by a disturbance in cellular lipid metabolism and most frequently affects children?

Gaucher's disease Signup and view all the answers

Which disorder has an average life expectancy of 5 years and involves massive accumulation of sphingomyelin due to enzyme deficiency?

Niemann-Pick Disease Signup and view all the answers

What is the main genetic inheritance pattern of Complement Receptor 3 (CR3) Deficiency?

Autosomal recessive Signup and view all the answers

What is the location of the Major Histocompatibility Complex (MHC) genes?

On the short arm of chromosome 6 Signup and view all the answers

What is the role of the MHC in the immune system?

It allows immune cells to distinguish self from non-self cells Signup and view all the answers

What is the main function of MHC Class I molecules?

To present cytoplasmatically derived antigens to CD8+ T cells Signup and view all the answers

Which cells express MHC Class II molecules?

Macrophages, B cells, dendritic cells, and antigen presenting cells Signup and view all the answers

What is the function of the MHC Class III region?

It encodes proteins involved in the complement system Signup and view all the answers

Abnormal Neutrophil Function Quiz

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Questions and Answers

Which cells in the immune system are responsible for phagocytosis of invaders?

Which cells present immunogens to T helper cells, the first step in an immune response?

Which type of cells have major histocompatibility complex (MHC) class II on their surface?

Which cells mediate IgE allergic responses in the immune system?

What is the main function of neutrophils in the immune system?

Which cells have receptors for IgE and granules responsible for allergic reactions?

What is the main characteristic of Chédiak-Higashi Syndrome?

Which disorder is characterized by a qualitative disorder of neutrophils with giant granules?

What is the main effect of Myeloperoxidase Deficiency on bacterial and fungal killing by phagocytes?

Which disorder is caused by a disturbance in cellular lipid metabolism and most frequently affects children?

Which disorder has an average life expectancy of 5 years and involves massive accumulation of sphingomyelin due to enzyme deficiency?

What is the main genetic inheritance pattern of Complement Receptor 3 (CR3) Deficiency?

What is the location of the Major Histocompatibility Complex (MHC) genes?

What is the role of the MHC in the immune system?

What is the main function of MHC Class I molecules?

Which cells express MHC Class II molecules?

What is the function of the MHC Class III region?

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