Abnormal Neutrophil Function Quiz
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Questions and Answers

Which cells in the immune system are responsible for phagocytosis of invaders?

  • Basophils
  • Neutrophils (correct)
  • Lymphocytes
  • Eosinophils

Which cells present immunogens to T helper cells, the first step in an immune response?

  • Monocytes
  • Macrophages (correct)
  • Eosinophils
  • Basophils

Which type of cells have major histocompatibility complex (MHC) class II on their surface?

  • Monocytes (correct)
  • Basophils
  • Neutrophils
  • Eosinophils

Which cells mediate IgE allergic responses in the immune system?

<p>Basophils (D)</p> Signup and view all the answers

What is the main function of neutrophils in the immune system?

<p>Phagocytosis and inflammatory response (A)</p> Signup and view all the answers

Which cells have receptors for IgE and granules responsible for allergic reactions?

<p>Eosinophils (B)</p> Signup and view all the answers

What is the main characteristic of Chédiak-Higashi Syndrome?

<p>Defective locomotion (A)</p> Signup and view all the answers

Which disorder is characterized by a qualitative disorder of neutrophils with giant granules?

<p>Chronic Granulomatous Disease (B)</p> Signup and view all the answers

What is the main effect of Myeloperoxidase Deficiency on bacterial and fungal killing by phagocytes?

<p>Mild defect in bacterial killing, marked defect in fungal killing (C)</p> Signup and view all the answers

Which disorder is caused by a disturbance in cellular lipid metabolism and most frequently affects children?

<p>Gaucher's disease (B)</p> Signup and view all the answers

Which disorder has an average life expectancy of 5 years and involves massive accumulation of sphingomyelin due to enzyme deficiency?

<p>Niemann-Pick Disease (B)</p> Signup and view all the answers

What is the main genetic inheritance pattern of Complement Receptor 3 (CR3) Deficiency?

<p>Autosomal recessive (B)</p> Signup and view all the answers

What is the location of the Major Histocompatibility Complex (MHC) genes?

<p>On the short arm of chromosome 6 (A)</p> Signup and view all the answers

What is the role of the MHC in the immune system?

<p>It allows immune cells to distinguish self from non-self cells (B)</p> Signup and view all the answers

What is the main function of MHC Class I molecules?

<p>To present cytoplasmatically derived antigens to CD8+ T cells (D)</p> Signup and view all the answers

Which cells express MHC Class II molecules?

<p>Macrophages, B cells, dendritic cells, and antigen presenting cells (D)</p> Signup and view all the answers

What is the function of the MHC Class III region?

<p>It encodes proteins involved in the complement system (C)</p> Signup and view all the answers

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