Neutropenia Overview and Treatment Options

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Questions and Answers

What type of immunodeficiency disorder is associated with large lysosomal granules in granulocytes and defective chemotaxis in neutrophils and monocytes?

  • Histiocytosis X
  • Hypophosphatasia
  • Ehlers-Danlos syndrome
  • Chediak-Higashi syndrome (correct)

What are the periodontal features of histiocytosis X?

  • Gingival overgrowth with minimal bone changes
  • Rapid tooth loss with normal periodontal tissues
  • Generalized enamel hypoplasia with mild gingivitis
  • Punched-out necrotic ulcers with granulation tissue and marked bone loss (correct)

Which syndrome is characterized by skin fragility, easy bruising, abnormal scarring, and early tooth loss?

  • Histiocytosis X
  • Hypophosphatasia
  • Chediak-Higashi syndrome
  • Ehlers-Danlos syndrome (correct)

What is a common treatment option for hypophosphatasia to address defective tooth mineralization and premature primary teeth loss?

<p>Extraction of mobile teeth (C)</p> Signup and view all the answers

Which disorder is characterized by suppressed monocyte chemotaxis, increased urinary excretion of phoshoethanolamine, and cementum hypoplasia leading to tooth issues?

<p>Hypophosphatasia (C)</p> Signup and view all the answers

What is a characteristic manifestation of histiocytosis X that may clinically resemble necrotizing ulcerative periodontitis lesions?

<p>Punched-out necrotic ulcers (A)</p> Signup and view all the answers

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