25 Questions
Which one of the following chemicals is not carcinogenic?
Ascorbic acid
Which one of the following descriptions of active wild-type p53 protein is incorrect?
p53 is encoded by an oncogene
Cancer cells do not display which of the following
Contact-inhibited growth
Which one of the following symptoms is NOT a paraneoplastic manifestation of tumours
Obstruction
The Epstein-Barr virus is most likely associated with which of the following?
Burkitt's lymphoma
Human papilloma virus (HPV) is most likely associated with which of the following?
Cervical cancer
Which of the following is an increase in tissue mass resulting from an increase in the size of its constituent cells?
Hypertrophy
Which of the following mechanisms might not be associated with oncogene activation?
Silent mutations in the coding regions of exons or in introns
Which of the following is not local effect due to the growth of tumour?
Cachexia
Which statement about Xeroderma Pigmentosum (XP) is false?
XP involves female only
Telomerase
is switched on in cancer cells
The active wild-type p53 protein normally promotes which one of the following:
cell apoptosis
When cancer causes clinical syndromes NOT as a result of its metastasis or local tissue invasion, this is termed as:
Paraneoplastic syndrome
Which one of the following is NOT a characteristic of cancer cells?
undergoing apoptosis
BRCA1 is most likely associated with which one of the following types of cancer?
Breast cancer
About 50% of all human cancers may involve an abnormal or missing
p53 gene
Which one of the following compounds is associated with increased risk of liver cancer?
aflatoxin
BRCA1 mutation is most likely associated with which one of the following types of cancer?
ovarian cancer
Which statement about PSA (prostate-specific antigen) is incorrect?
PSA concentrations in the blood can be used to distinguish between prostate cancer and non- cancerous conditions
When cancer causes clinical syndromes NOT as a result of its metastasis or local tissue invasion, this is termed as:
Paraneoplastic syndrome
Which of these is the incrase in tissue mass after cell divison
Hyperplasia
The formation of an inherited retinoblastoma is associated with the mutations of:
RB (Rb) gene
Which one of the following statement is incorrect?
RANK ligand (RANKL) released by myeloma cells stimulates osteoblasts that contribute to hypercalcemia
Which one of the following tumour markers is most likely associated with breast cancer?
cancer antigen 15-3 (CA 15-3)
All of the following effects are disadvantages of anticancer drugs, EXCEPT
Depression of angiogenesis
Test your knowledge of cancer biology with this quiz covering topics such as carcinogenic chemicals, p53 protein, cancer cell characteristics, paraneoplastic manifestations, and associations of viruses like Epstein-Barr and human papilloma virus (HPV) with cancer.
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